Adding a certain compound to certain chemical reactions, such as: 106877-33-2, 5-Amino-2-(trifluoromethyl)pyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 5-Amino-2-(trifluoromethyl)pyridine, blongs to pyridine-derivatives compound. Recommanded Product: 5-Amino-2-(trifluoromethyl)pyridine
Example 4; 5-amino-l-(3-(pyrrolidin-l-ylmethyl)benzyl)-7-(trifluoromethyl)pyrMdionePreparation of 2-chloro-6-(trifluoromethyl)pyridin-3-amine (19)[000396] To a solution of 6-(trifluoromethyl)pyridin-3-amine (18) (1 equiv) (commercially available) in CH3CN (0.25M) was added N-cholorosuccinimide (1 equiv) and stirred at 80 C for 2 hours. The mixture was then cooled down to room temperature and concentrated en vaccuo. The residue was purified by Combi-Flash using 0-20% EtOAc in hexane to afford 2-chloro-6- (trifluoromethyl)pyridin- 3 – amine (19).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,106877-33-2, 5-Amino-2-(trifluoromethyl)pyridine, and friends who are interested can also refer to it.
Reference:
Patent; IRM LLC; CORTEZ, Alex; LI, Yongkai; LIAO, Xuebin; WU, Tom Yao-Hsiang; ZHANG, Xiaoyue; WO2011/57148; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem