Related Products of 33674-96-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 33674-96-3, name is (6-Bromopyridin-2-yl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
To a mixture of ( 6-bromopyridin-2-yl) methanol (5.22 g) , PPh3 (8.74 g) and benzotrifluoride (210 mL) was added tetrabromomethane (11.1 g) at 0C. The mixture was stirred at 0C for 2 hr, and the insoluble substance was removed by filtration, and washed with ethyl acetate/diethyl ether. The filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (7.33 g) . XH NMR (300 MHz, CDCI3) delta 4.50 (2H, s) , 7.39-7.45 (2H, m) , 7.52-7.60 (1H, m) .
According to the analysis of related databases, 33674-96-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; KAJITA, Yuichi; MIKAMI, Satoshi; MIYANOHANA, Yuhei; KOIKE, Tatsuki; DAINI, Masaki; OYABU, Norio; OGINO, Masaki; TAKEUCHI, Kohei; ITO, Yoshiteru; TOKUNAGA, Norihito; SUGIMOTO, Takahiro; MIYAZAKI,Tohru; ODA, Tsuneo; HOASHI, Yasutaka; HATTORI,Yasushi; IMAMURA, Keisuke; (413 pag.)WO2019/27058; (2019); A1;,
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