64436-92-6, Adding a certain compound to certain chemical reactions, such as: 64436-92-6, 3-Amino-5-methoxypyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 64436-92-6, blongs to pyridine-derivatives compound.
5-Methoxypyridin-3-ol A mixture of concentrated sulfuric acid (18 M, 2.83 mL), water (3.84 mL) and crushed ice (6.60 g) was added to 5-methoxy-3-pyridylamine (1.64 g, 13.23 mmol). The cold mixture (0-5 C.) was stirred for 10 min and a solution of sodium nitrite (0.91 g, 13.23 mmol) in water (2.7 mL) was then added. After stirring for 10 min, a boiling solution of concentrated sulfuric acid (8.6 mL) and water (6.6 mL) was added. The mixture was heated until all solids dissolved. Ice (5.0 g) was added to cool the solution. The pH was adjusted to 8 with 10% NaOH solution. Saturated NaCl solution (100 mL) was added, and the mixture was extracted with ethyl acetate (4*100 mL). The combined ethyl acetate extracts were dried (MgSO4), filtered and concentrated by rotary evaporation to give 0.50 g (30.1%) of a brown oil.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,64436-92-6, its application will become more common.
Reference:
Patent; DULL, GARY MAURICE; WAGNER, JARED MILLER; HADIMANI, SRISHAIKUMAR BASAWANNAPPA; CONSILVIO, MICHAEL B.; US2001/14691; (2001); A1;; ; Patent; DULL, GARY MAURICE; REICH, ERIN E.; WAGNER, JARED MILLER; BHATTI, BALWINDER SINGH; CONSILVIO, MICHAEL B.; US2001/31771; (2001); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem