Day: January 14, 2022

An article Practical catalytic nitration directly with commercial nitric acid for the preparation of aliphatic nitroesters WOS:000565016900005 published article about RECYCLABLE CATALYSTS; ALKYL NITRATES; THERAPY in [An, Jichao; Liu, Peipei; Si, Mengyuan; Li, Wenhao; He, Pan; Yang, Bo; Yang, Guanyu] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Peoples R China in 2020, Cited 23. COA of Formula: C8H9NO2. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6

To pursue a sustainable and efficient approach for aliphatic nitroester preparation from alcohol, europium-triflate-catalyzed nitration, which directly uses commercial nitric acid, has been successfully developed. Gram scalability with operational ease showed its practicability.

Recommanded Product: 614-18-6. Bye, fridends, I hope you can learn more about C8H9NO2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

In 2020.0 SYNTHETIC COMMUN published article about ASYMMETRIC TRANSFER HYDROGENATION; BAKERS-YEAST; BIOCATALYSIS; REDUCTION; ALCOHOL; BIOREDUCTION; ACETOPHENONE; FLAVONOIDS; RESOLUTION in [Sahin, Engin] Bayburt Univ, Dept Food Engn, Fac Engn, TR-69000 Bayburt, Turkey in 2020.0, Cited 58.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Recommanded Product: 91-02-1

Aryl and heteroaryl chiral carbinols are useful precursors in the synthesis of drugs. Lactobacillus paracasei BD87E6, which is obtained from a cereal based fermented beverage, was investigated as whole cell biocatalyst for the bioreduction of different ketones (including aromatic, hetero-aromatic and fused bicyclic ketone) into chiral carbinols, which can be used as a pharmaceutical intermediate. The study shows that bioreduction of aryl, heteroaryl and fused bicyclic ketone (1-5) to their corresponding chiral carbinols (1a-5a) in excellent enantioselectivity (>99%) with high yields. This study gave the first example for an enantiopure production of (S)-6-chlorochroman-4-ol (3a), which has many antioxidant activity, by a biological method. For asymmetric bioreduction of other prochiral ketones, these results open way to use of L. paracasei BD87E6 as biocatalysts. Also, the present process shows a hopeful and alternative green synthesis for the production of enantiopure carbinols in a mild, inexpensive and environmentally friendly process.

Recommanded Product: 91-02-1. Welcome to talk about 91-02-1, If you have any questions, you can contact Sahin, E or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Safety of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Recently I am researching about X-RAY-STRUCTURE; METAL-COMPLEXES; BIOLOGICAL EVALUATION; CRYSTAL-STRUCTURE; DNA-BINDING; METHYLDITHIOCARBAZATE SMDTC; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; CIRCULAR-DICHROISM; ZN(II) COMPLEXES, Saw an article supported by the Fundacao para a Ciencia e Tecnologia (FCT)Portuguese Foundation for Science and TechnologyEuropean Commission [UIDB/00100/2020, UIDP/00100/2020, PTDC/QUI-QAN/32242/2017, UID/Multi/00709/2019, UIDB/50006/2020, UIDB/04378/2020, SAICTPAC/0019/2015, PD/BD/128320/2017]; Programa Operacional Regional de Lisboa [LISBOA-01-0145-FEDER-007317]; FEDER fundsEuropean Commission [POCI-01-0145-FEDER-007491]. Published in ELSEVIER SCIENCE INC in NEW YORK ,Authors: Ramilo-Gomes, F; Addis, Y; Tekamo, I; Cavaco, I; Campos, DL; Pavan, FR; Gomes, CSB; Brito, V; Santos, AO; Domingues, F; Luis, A; Marques, MM; Pessoa, JC; Ferreira, S; Silvestre, S; Correia, I. The CAS is 65-22-5. Through research, I have a further understanding and discovery of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Schiff bases (SB) obtained from S-methyl dithiocarbazate and aromatic aldehydes: salicylaldehyde (H2L1), ovanillin (H2L2), pyridoxal (H2L3) and 2,6-diformyl-4-methylphenol (H3L4), and their corresponding Zn(II)complexes (1-4), are synthesized. All compounds are characterized by elemental analyses, infrared, UV-Vis, nuclear magnetic resonance spectroscopy and mass spectrometry. The structures of H2L2 and [Zn-2(L-1)(2)(H2O) (DMF)] (1a) (DMF = dimethylformamide) are solved by single crystal X-ray diffraction. The SB coordinates the metal center through the Ophenolate, Nimine and Sthiolate atoms. The radical scavenging activity is tested using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, with all ligand precursors showing IC50 values similar to 40 mu M. Cytotoxicity studies with several tumor cell lines (PC-3, MCF-7 and Caco-2) as well as a non-tumoral cell line (NHDF) are reported. Interestingly, 1 has relevant and selective antiproliferative effect against Caco-2 cells (IC50 = 9.1 mu M). Their antimicrobial activity is evaluated in five bacterial strains (Klebsiella pneumoniae, Acinetobacter baumannii, Listeria monocytogenes, Pseudomonas aeruginosa and Staphylococcus aureus) and two yeast strains (Candida albicans and Candida tropicalis) with some compounds showing bacteriostatic and fungicidal activity. The minimal inhibitory concentration (MIC90) of HnL against Mycobacterium tuberculosis is also reported, with H2L2 and H3L4 showing very high activity (MIC90 < 0.6 mu g/mL). The ability of the compounds to bind bovine serum albumin (BSA) and DNA is evaluated for H3L4 and [Zn-2(L-4)(CH3COO)] (4), both showing high binding constants to BSA (ca. 106 M 1) and ability to bind DNA. Overall, the reported compounds show relevant antitumor and antimicrobial properties, our data indicating they may be promising compounds in several fields of medicinal chemistry. Safety of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Bye, fridends, I hope you can learn more about C8H10ClNO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

COA of Formula: C8H9NO2. Authors Chen, ZP; Tang, HQ; Ou, CR; Xie, C; Cao, JX; Zhang, X in WILEY published article about in [Chen, Zhipeng; Ou, Changrong; Xie, Cheng; Cao, Jinxuan; Zhang, Xin] Ningbo Univ, Coll Food & Pharmaceut Sci, Dept Food Sci & Engn, Ningbo, Peoples R China; [Tang, Haiqing] Zhejiang Pharmaceut Coll, Fac Food Sci, Dept Food Nutr & Testing, Ningbo, Peoples R China in 2021, Cited 153. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6

Volatiles of four zaoyu (Chinese traditional fermented fish) products prepared from different species of marine fish were analyzed by headspace solid-phase micro-extraction (HS-SPME) and comprehensive two-dimensional gas chromatography in combination with time-of-flight mass spectrometry (GC x GC/TOFMS). First, a 50/30 mu m DVB/CAR/PDMS was used and the influence of several parameters on the efficiency of HS-SPME such as extraction temperature, time, salting-out effect, and stirring were optimized, odor activity values (OAVs) of volatile compounds were computed based on the threshold values of aroma constituents; the characteristic volatiles and their odor characteristics of the four zaoyu were investigated. The results demonstrated that the most effective extraction of the analytes was obtained with a 40 min extraction at 50 degrees C with the addition of 20% NaCl and stirring at 300 r/min. Under these conditions, a total of 288 volatile components were tentatively identified based on mass spectra and comparison of linear retention indices in the four zaoyu products. Authenticated compounds included aldehydes, esters, alcohols, ketones, furans, lactones, nitrogen compounds, sulfur compounds, terpenes, phenols, etc. Among the identified types of volatile compounds, the number of esters is the largest, whereas the content of aldehydes is the highest. The results of OAVs comparisons proved that both aldehydes and esters provided the most significant contribution to the aromas of zaoyu, and each zaoyu product had its own unique active flavor components. Moreover, the OAVs of active flavor compounds common to the four examined zaoyu varied significantly. Our results substantiated that GC x GC/TOFMS could provide a robust technical means to understand the flavor characteristics of zaoyu and allow us to better evaluate and improve the flavor quality of the products with complex food matrix like zaoyu. Practical applications The method present in this research is suitable to characterize the volatile constituents of aquatic products, and could also be used for component characterization of similar complex samples such as fermented fish and foods. Understanding the key aroma compounds of fermented fish and its formation mechanism could provide a guide of process optimization and flavor regulation, contributing to further studies related to volatile compounds in the field of food flavor analysis.

Welcome to talk about 614-18-6, If you have any questions, you can contact Chen, ZP; Tang, HQ; Ou, CR; Xie, C; Cao, JX; Zhang, X or send Email.. COA of Formula: C8H9NO2

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

SDS of cas: 65-22-5. Chen, XY; Li, H; Luo, HJ; Lin, ZX; Luo, WH in [Chen, Xuyang; Li, Hui; Luo, Hongjun; Lin, Zhexuan; Luo, Wenhong] Shantou Univ, Coll Med, Bioanalyt Lab, Xinling Rd 22, Shantou, Guangdong, Peoples R China published Synthesis and Evaluation of Pyridoxal Hydrazone and Acylhydrazone Compounds as Potential Angiogenesis Inhibitors in 2019.0, Cited 45.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5.

Background/Aims: Hydrazone and acylhydrazone derivatives, which are produced from aldehyde reacting with hydrazine or acylhydrazine, have been reported to exhibit antitumor activities. However, the angionenic effects of this kind of derivatives haven’t been elucidated. Here, we synthesized 12 pyridoxal hydrazone and acylhydrazone compounds and investigated their antiangiogenic effects and the underlying mechanisms. Method: 3-(4,5-Dimethylthiazol-2-yl)-2, 5-dipheyltetrazolium bromide assay was used to screen the inhibitory effects of the synthesized compounds on endothelial cells (ECs) proliferation. The compound with best inhibitory effect was further evaluated with wound-healing assay and tube formation assay. Calcein-Am assay was carried out to determine the content of intracellular labile iron pool (LIP). Intracellular reduced glutathione (GSH) was determined by spectrophotometry. Flow cytometry was used to determine cell cycle and apoptosis. Results: Compound 10 (3-hydroxy-5-[hydroxymethyl]-2-methyl-pyridine-4-carbaldehyde-2-naphthalen-1-acetyl hydrazone) showed the best inhibitory effect on human umbilical vascular ECs proliferation, with IC50 value of 25.4 mu mol/L. It not only inhibited wound-healing and tube formation of ECs, but also decreased the content of intracellular LIP and GSH. Furthermore, it arrested ECs cycle at S phase and induced cell apoptosis. Conclusions: Compound 10 exhibits antiangiogenic effects by reducing the content of intracellular LIP and GSH, and subsequently arresting cell cycle and inducing cell apoptosis.

About 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride, If you have any questions, you can contact Chen, XY; Li, H; Luo, HJ; Lin, ZX; Luo, WH or concate me.. Computed Properties of C8H10ClNO3

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

HPLC of Formula: C8H9NO2. Authors Wasfy, N; Doan, B; Rasheed, F; Fishlock, D; Orellana, A in AMER CHEMICAL SOC published article about in [Wasfy, Nour; Doan, Brian; Rasheed, Faizan; Orellana, Arturo] York Univ, Dept Chem, Toronto, ON M3J 1P3, Canada; [Fishlock, Dan] F Hoffmann La Roche Ltd, Synthet Mol Tech Dev, Proc Chem & Catalysis, CH-4070 Basel, Switzerland in 2021, Cited 61. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6

We report a mild palladium-catalyzed selective dehydrogenation of 4-alkylpyridines that exploits their soft enolization to alkylidene dihydropyridines using allyl chloroformate under metal-free conditions. Treatment of these intermediates with a palladium catalyst liberates an alkylpyridylic anion and an allylpalladium(II) intermediate, which combine and undergo beta-hydride elimination to install a double bond. Importantly, the formation of gas byproducts makes the process very practical. Furthermore, the reaction tolerates a broad range of functional groups, including many that can be dehydrogenated using similar palladium-catalyzed reactions, and is selective for 4-alkylpyridines even in substrates bearing multiple pyridylic positions.

Bye, fridends, I hope you can learn more about C8H9NO2, If you have any questions, you can browse other blog as well. See you lster.. Product Details of 614-18-6

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

I found the field of Chemistry very interesting. Saw the article Unravelling the potency of 4,5-diamino-4H-1,2,4 triazole-3-thiol derivatives for kinase inhibition using a rational approach published in 2019.0. Recommanded Product: 500-22-1, Reprint Addresses DuttKonar, A (corresponding author), Rajiv Gandhi Technol Univ, Sch Pharmaceut Sci, Airport Bypass Rd, Bhopal 462033, India.; DuttKonar, A (corresponding author), Rajiv Gandhi Technol Univ, Dept Chem, Bhopal, India.. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde

The discovery of potent kinase inhibitors with tunable selectivity and specificity has gained significant impetus in the last few decades. In accordance with this development, herein, we report the design and synthesis of a series of new heterocyclic derivatives comprising a 1,2,4 triazole nucleus, tethered to two flexible linkers on either side, utilizing a simple Schiff base approach (compounds 1-16). The compounds were characterised by various spectroscopic techniques and their biological evaluation was conducted using kinase inhibition assay on two targets, namely CLK1 and DYRK1A. Our investigation reveals that compounds 3-5 bearing hydroxy/methoxy substituents in the aromatic ring display excellent potency towards the receptors in the micromolar range. Indeed, compound 5 bearing a methoxy substitution at the meta position possesses the added advantage of being highly specific towards CLK1 among the targets. To reinforce this observation, we performed molecular modelling studies with the kinase inhibitors hymenialdisine (HMD) cocrystallized with CLK1 and harmine (HA) cocrystallized with DYRK1A kinases as references. We speculate that in either target, the cause of such high potency and selectivity might be attributed to the involvement of flexible linkers on either side of the triazole core, which might have compelled the ligands to enter into the active site of the receptor and maximize non-covalent interactions. Interestingly, we consider the selectivity of compound 5 to be due to the involvement of a H-bond between SH of triazole and Glu 169 carbonyl in the receptor, which is absent in the other derivatives for both targets. Thus, our efforts focus on how the variation/position of substituents in the inhibitors has a profound impact on potency and selectivity. Indeed, this work establishes innovative design principles towards the development of a therapeutic agent for the treatment of neurodegenerative diseases like that of Alzheimers.

Welcome to talk about 500-22-1, If you have any questions, you can contact Jain, AK; Karthikeyan, C; McIntosh, KD; Tiwari, AK; Trivedi, P; DuttKonar, A or send Email.. Recommanded Product: 500-22-1

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

In 2020.0 BIOORG CHEM published article about BIOLOGICAL EVALUATION; MOLECULAR-MECHANISMS; CINNAMALDEHYDE; DESIGN; REACTIVITY; INHIBITORS; TOXICITY in [Omar, Abdelsattar M.; El-Araby, Moustafa E.; Malebari, Azizah M.] King Abdulaziz Univ, Fac Pharm, Dept Pharmaceut Chem, Jeddah 21589, Saudi Arabia; [Omar, Abdelsattar M.] Al Azhar Univ, Fac Pharm, Dept Pharmaceut Chem, Cairo 11884, Egypt; [Abdelghany, Tamer M.; Abdel-Bakky, Mohamed S.] Al Azhar Univ, Fac Pharm, Dept Pharmacol, Cairo 11884, Egypt; [Safo, Martin K.; Ahmed, Mostafa H.] Virginia Commonwealth Univ, Dept Med Chem, Sch Pharm, Richmond, VA 23298 USA; [Safo, Martin K.; Ahmed, Mostafa H.] Virginia Commonwealth Univ, Inst Struct Biol Drug Discovery & Dev, Sch Pharm, Richmond, VA 23298 USA; [Boothello, Rio; Patel, Bhaumik B.] Virginia Commonwealth Univ, Dept Med, Div Hematol & Oncol, Richmond, VA 23298 USA; [Boothello, Rio; Patel, Bhaumik B.] Massey Canc Ctr, Richmond, VA 23298 USA; [Boothello, Rio; Patel, Bhaumik B.] Hunter Holmes McGuire VA Med Ctr, Richmond, VA 23249 USA; [Ahmed, Hany E. A.] Taibah Univ, Coll Pharm, Pharmacognosy & Pharmaceut Chem, Al Madinah Al Munawarah 47114, Saudi Arabia; [Ahmed, Hany E. A.] Al Azhar Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Cairo 11884, Egypt; [Elhaggar, Radwan S.] Helwan Univ, Fac Pharm, Dept Pharmaceut Chem, Cairo 11790, Egypt in 2020.0, Cited 38.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1. HPLC of Formula: C6H5NO

Curcumin and trans-cinnamaldehyde are acrolein-based Michael acceptor compounds that are commonly found in domestic condiments, and known to cause cancer cell death via redox mechanisms. Based on the structural features of these compounds we designed and synthesized several 2-cinnamamido-N-substituted-cinnamamide (bis-cinnamamide) compounds. One of the derivatives, (Z)-2-[(E)-cinnamamido]-3-phenyl-N-propylacrylamide 8 showed a moderate antiproliferative potency (HCT-116 cell line inhibition of 32.0 mu M), no inhibition of normal cell lines C-166, and proven cellular activities leading to apoptosis. SAR studies led to more than 10-fold increase in activity. Our most promising compound, [(Z)-3-(1H-indol-3-yl)-N-propyl-2-[(E)-3-(thien-2-yl)propenamido) propenamide] 45 killed colon cancer cells at IC50 = 0.89 mu M (Caco-2), 2.85 mu M (HCT-116) and 1.65 mu M (HT -29), while exhibiting much weaker potency on C-166 and BHK normal cell lines (IC50 = 71 mu M and 77.6 mu M, respectively). Cellular studies towards identifying the compounds mechanism of cytotoxic activities revealed that apoptotic induction occurs in part as a result of oxidative stress. Importantly, the compounds showed inhibition of cancer stem cells that are critical for maintaining the potential for self-renewal and stemness. The results presented here show discovery of covalently acting Michael addition compounds that potently kill cancer cells by a defined mechanism, with prominent selectivity profile over non-cancerous cell lines.

HPLC of Formula: C6H5NO. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Omar, AM; El-Araby, ME; Abdelghany, TM; Safo, MK; Ahmed, MH; Boothello, R; Patel, BB; Abdel-Bakky, MS; Malebari, AM; Ahmed, HEA; Elhaggar, RS or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Song, PD; Hu, LL; Yu, T; Jiao, J; He, YQ; Xu, L; Li, PF in AMER CHEMICAL SOC published article about C(SP(3))-H BORYLATION; BIPYRIDINE LIGAND; ARENES; ACTIVATION; COMPLEXES; CYCLOPROPANATION; C(SP(2))-H; FUNCTIONALIZATION; BONDS in [Song, Peidong; Yu, Tao; Li, Pengfei] Xi An Jiao Tong Univ, Frontier Inst Sci & Technol, Xian 710054, Peoples R China; [Hu, Linlin; He, Yangqing] Xian Univ Technol, Dept Appl Chem, Xian 710048, Peoples R China; [Jiao, Jiao] Xi An Jiao Tong Univ, Sch Chem, Xian Key Lab Sustainable Energy Mat Chem, Xian 710049, Peoples R China; [Xu, Liang] Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832003, Peoples R China; [Li, Pengfei] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China in 2021.0, Cited 104.0. Name: Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Although pyridine derivatives are versatile supporting ligands in catalysis, the development of their chiral versions has been relatively limited. Herein, we report the design, synthesis, and proof-of-concept application of a structurally tunable chiral pyridine framework featuring an annulated compact ring system. Using an N,B-bidentate ligand skeleton containing the chiral pyridine moiety, we have developed an enantioselective iridium-catalyzed desymmetrizing C-H borylation reaction of diaryl(2-pyridyl)methane compounds with up to 96% ee and 93% yield. The resulting borylation products could be readily transformed into various chiral tri(hetero)arylmethane compounds. Density functional theory investigations revealed that the two chair conformations of the flexible ketal motif both favored the enantiomer that was consistent with experimental results. This work has thus introduced an effective and tunable chiral pyridine ligand framework that may be used in many catalytic asymmetric transformations.

Name: Phenyl(pyridin-2-yl)methanone. Welcome to talk about 91-02-1, If you have any questions, you can contact Song, PD; Hu, LL; Yu, T; Jiao, J; He, YQ; Xu, L; Li, PF or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. Recently I am researching about C-H BONDS; COUPLED ELECTRON-TRANSFER; DIRECT ARYLATION; ACTIVATION; CATALYSIS; FUNCTIONALIZATION; ALDEHYDES; HALIDES; MERGER, Saw an article supported by the National Research Foundation [NRF2016NRF-NSFC002-005]; Ministry of Education, SingaporeMinistry of Education, Singapore [MOE 2013-T3-1-002]; MOE Tier 1 grantMinistry of Education, Singapore [RG 111/18]; Agency for Science, Technology and Research (A*STAR), AME IRG grantAgency for Science Technology & Research (ASTAR) [A1783c0002]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Vu, MD; Das, M; Guo, AX; Ang, ZE; Dokic, M; Soo, HS; Liu, XW. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Being a handle for synthesizing quaternary carbon centers and olefins, together with ubiquitous appearance in organic building blocks, makes tertiary alcohols valuable targets in synthesis. However, traditional syntheses of these alcohols have faced several challenges including the employment of functionalized reactive reagents, undesirable side reactions, and decomposition of the alcohol products under harsh conditions. The paucity of a synthetic approach to bulky tertiary alcohols prompts our interest to develop a benign catalytic protocol to tackle the current issues. Here, we have successfully demonstrated the use of ketyl radicals in intermolecular cross radical-radical coupling, which has opened a different door for accessing complex tertiary alcohols. On the other hand, by starting from feedstock and naturally derived chemicals without any pre-activation, it would be superior to traditional methodologies in the industrial context.

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem