Month: October 2022

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Electric Literature of 766-11-0.

Zhu, Qiming;Yang, Peng;Chen, Mingwei;Hu, Jinyu;Yang, Luyi research published 《 A Rapid Method to Aromatic Aminoalkyl Esters via the Catalyst-Free Difunctionalization of C-N Bonds》, the research content is summarized as follows. A novel multicomponent reaction involving a direct C-N esterification/arylation has been developed. This catalyst-free process was conducted with cyclic tertiary amines via a facile C-N cleavage to provide the alkyl group and nitrogen source. The operationally simple method to rapidly combine cyclic tertiary amines, haloazaarenes and carboxylic acids (or anhydrides) affords an efficient access to aromatic aminoalkyl esters, I (R = Me, Et, n-Pr, Ph, etc.; Ar = 2-pyridyl, 5-Br-2-pyridyl, etc.), potential drug-like products, in good to excellent yields.

Electric Literature of 766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , 766-11-0.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. For this reason, pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Computed Properties of 766-11-0.

Zhu, Qiming;Chen, Mingwei;Hu, Jinyu;Yang, Luyi research published 《 Facile N-Alkylation/N’-Arylation Process: A Direct Approach to Aromatic Aminoalkyl Amines》, the research content is summarized as follows. An intriguing C-N transformation involving a catalyst-free N-alkylation/N’-arylation process in a multicomponent reaction with secondary amines, cyclic tertiary amines and electron-deficient aryl halides has been described. In this case, the N-alkylation of secondary amines, utilizing cyclic tertiary amines as alkyl group sources, is enabled by a facile C-N cleavage. Such an operationally simple method could facilitate access to aromatic aminoalkyl amines, nitrogen-containing bioactive mols., in good to excellent yields.

Computed Properties of 766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , 766-11-0.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Quality Control of 766-11-0.

Zhu, Qiming;Yuan, Qinghe;Chen, Mingwei;Guo, Mengping;Huang, Hanmin research published 《 Multicomponent Reactions with Cyclic Tertiary Amines Enabled by Facile C-N Bond Cleavage》, the research content is summarized as follows. A novel and catalyst-free multicomponent reaction with cyclic tertiary amines, electron-deficient aryl halides or heteroaromatic halides, and Na₂S enabled by facile C-N bond cleavage of the cyclic tertiary amines was developed. This direct and operationally simple method can be applied with a wide range of functional groups and provides an efficient and rapid approach to potentially drug-like products containing amine, azaarene, thioether, or phenol ether functionalities in good to excellent yields. The utility of this method was demonstrated by the rapid synthesis of the analgesic ruzadolane.

766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , Quality Control of 766-11-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Quality Control of 1603-41-4.

Zhu, Kongyun;Liu, Qiutong;Dang, Chao;Li, Aimin;Zhang, Lei research published 《 Valorization of hydrothermal carbonization products by anaerobic digestion: Inhibitor identification, biomethanization potential and process intensification》, the research content is summarized as follows. Integrating hydrothermal carbonization (HTC) and anaerobic digestion for biorefinery-oriented full utilization of wet organic wastes is a promising emerging technol. The objectives of this study were to identify the potential inhibitory substances, evaluate the biomethane potential of mixed and aqueous products and explore process intensifying strategies. The results indicated that the high HTC temperature of 240 °C resulted in a significantly low methane yield of 60 ± 5 mL/g COD and a high Short chain fatty acid (SCFAs) accumulation of 4174 ± 76 mg/L. GC-MS anal. showed that the contents of inhibitory pyrazines, pyridines and ketones in aqueous fraction at 240 °C substantially increased from 13.14%, 0.4%, 0.55% at 180 °C to 23.34%, 2.89%, 5.13%, resp. When the aqueous products obtained from 240 °C-HTC was supplemented or pretreated by carbonaceous material, the methane yields were greatly improved and increased to 1.3-fold and 1.8-fold, resp. These finding could provide some valuable tech. information for HTC based biorefinery of organic waste.

Quality Control of 1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Recommanded Product: 5-Bromopicolinaldehyde.

Zhu, Huiling;Liu, Peng;Liu, Hongxin;Ahmed, Ebrahim-Alkhalil M. A.;Hu, Xingen;Li, Juan;Xiao, Hong-Ping;Li, Xinhua;Jiang, Jun research published 《 Asymmetric synthesis of δ-substituted-β-keto esters and β-substituted ketones via carboxyl-assisted site- and enantio-selective addition reactions》, the research content is summarized as follows. Carboxyl-assisted site- and enantio-selective additions of polyfunctional nucleophiles to imines and carbonyls were developed, affording δ-substituted-β-keto esters and β-substituted ketones with good yields and enantioselectivities. Besides, short synthetic routes to bioactive mols. were also achieved.

31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., Recommanded Product: 5-Bromopicolinaldehyde

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Name: Pyridine-3-sulfonyl chloride.

Zhou, Zheng;Liu, Qianqian;Huang, Zhibin;Zhao, Yingsheng research published 《 A Bi(OTf)₃-Promoted Hydrosulfonylation of Alkenes with Sulfonyl Hydrazides: An Approach to Branched Sulfones》, the research content is summarized as follows. The Bi(OTf)₃-promoted hydrosulfonylation of alkenes with sulfonyl hydrazides to produce branched sulfones was reported, in which various branched sulfones (≥40 examples) were prepared in moderate to good yields. The gram-scale reaction and synthesis of the exptl. inhibitor precursor showed the potential application. A preliminary mechanistic study revealed that double-bond migration to form the α,β-conjugated alkene is crucial for this transformation.

Name: Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Reference of 1603-41-4.

Zhou, Yong-Jun;Yang, Kai;Fang, Yong-Gan;Luo, Shi-He;Chen, Qi;Yu, Shi-Wei;Wang, Zhao-Yang research published 《 A NaHCO₃ Promoted Three-component Cyclization: Easy Access to Benzodisulfide Heterocycles》, the research content is summarized as follows. A facile route for the synthesis of benzodisulfide heterocyclic compounds I (R = H, 5-Cl, 5-Br, 6-F, 6-OMe; Ar = C₆H₅, 2-CH₃C₆H₄, 2-pyridyl, etc.) via a NaHCO₃-promoted three-component reaction between 2-halophenylacetic acids R¹-2-X-C₆H₃CH₂COOH (R¹ = H, 5-Cl, 5-Br, 4-F, 4-OMe; X = Cl, Br), elemental sulfur (S8) and amines ArNH₂ under metal-free conditions has been demonstrated. This transformation from available starting materials shows good functional group tolerance, and the target compounds I can be derivatized for further application.

1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, Reference of 1603-41-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. Recommanded Product: 2-Bromo-6-methylpyridine.

Zhou, Yi;He, Piao;Mo, Xiu-Fang;Liu, Chao;Gan, Zhi-Liang;Tong, Hai-Xia;Yi, Xiao-Yi research published 《 Neutral cyclometalated Ir(III) complexes with pyridylpyrrole ligand for photocatalytic hydrogen generation from water》, the research content is summarized as follows. To explore structure-activity relationships with respect to light-harvesting behavior, a family of neutral iridium complexes [Ir(ppy)₂(L_R)] 1-4 (where ppy = 2-phenylpyridine, and N̂N = 2-(1H-pyrrol-2-yl)pyridine and its functionalized derivatives) were designed and synthesized. The structural modifications in metal complexes are accomplished through the attributions of electron-donating CH₃ in 2, OCH₃ in 3, and electron-withdrawing CF₃ in 4. The structural anal. displays that the pyridylpyrrole acts as one-neg. charged bidentated ligand to chelate the iridium center. The electrochem. and photophys. properties of these complexes were systematically studied. The neutral 1-4 as well as the ionic structurally analogous [Ir(ppy)₂(bpy)](PF₆) (5) were utilized as PSs in photocatalytic hydrogen generation from water with [Co(bpy)₃](PF₆)₂ as catalyst and triethanolamine (TEOA) as electron sacrificial agent in the presence of salt LiCl. Complex 1 maintains activity for more than 144 h under irradiation, and the total turnover number is up to 1768. The electrochem. properties and the quenching reaction indicate the H₂ generation by neutral complexes 1-4 is involved exclusively in the oxidative quenching process.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Recommanded Product: 2-Bromo-6-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. Category: pyridine-derivatives.

Zhou, Xibing;Chen, Anrong;Du, Wei;Wang, Yawen;Peng, Yu;Huang, Hanmin research published 《 Palladium-Catalyzed Hydrocarbonylative Cyclization Enabled by Formal Insertion of Aromatic C=N Bonds into Pd-Acyl Bonds》, the research content is summarized as follows. An efficient new formal insertion strategy via combination of reductive elimination and oxidative addition sequence was reported, in which the transient N-acyliminium ions formed via hydrocarbonylation function as key intermediates. This strategy has enabled a novel palladium-catalyzed hydrocarbonylative cyclization of azaarene-tethered alkenes or dienes via sequential insertion of a C=C bond, CO, and a C=N bond into palladium-hydride bonds. This method provides a new and highly efficient synthetic approach to quinolizinones and its derivatives with extended π-conjugated systems, possessing tunable emission wavelengths and good photoluminescence capabilities.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Application In Synthesis of 16133-25-8.

Zhou, Xiaocong;Hu, Dufen;He, Xinyi;Li, Yuanqiang;Chu, Youqun;She, Yuanbin research published 《 Practical and efficient synthesis of aryl trifluoromethyl sulfones from arylsulfonyl chlorides with Umemoto’s reagent II》, the research content is summarized as follows. A practical and efficient method for the synthesis of aryl trifluoromethyl sulfones RSO₂CF₃ (R = Ph, 4-MeC₆H₄, 3-pyridyl, 2-thienyl, etc.) has been developed by a tandem reaction of arylsulfonyl chlorides with Umemoto’s reagent II. The advantageous features of this method are simple operation, mild reaction conditions, wide scope of substrates, high yield of products, and easy scalability.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Application In Synthesis of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem