Day: October 13, 2022

Related Products of 98-98-6In 2021 ,《Concentration effects on optical properties, DFT, crystal characterization and α-glucosidase activity studies: Novel Zn(II) complex》 appeared in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy. The author of the article were Dege, Necmi; Ozge, Ozgen; Avci, Davut; Basoglu, Adil; Sonmez, Fatih; Yaman, Mavise; Tamer, Omer; Atalay, Yusuf; Zengin Kurt, Belma. The article conveys some information:

A novel Zn(II) complex of 6-ClpicH and picH was synthesized and its structure was determined by XRD technique. The detailed exptl. optical susceptibility and band gap, refractive index, linear polarizability, optical and elec. conductivity parameters in various concentrations were studied by the UV-visible spectroscopic data. The optical band gap, refractive index (n), linear optical susceptibility (χ(1)), third-order nonlinear optical susceptibility (χ(3)), second- and third-order nonlinear optical (β and γ) parameters were examined by using DFT/M06-L and ωB97XD/6-311++G(d,p) levels. The IC50 value of Zn(II) complex against α-glucosidase was also obtained at 0.44 mM. The exptl. band gap of the Zn(II) complex at 13, 33, 44 and 94μM concentrations in ethanol are 4.38, 4.37, 4.35 and 4.28 eV, resp. The third-order NLO susceptibility χ(3) parameter at 94μM concentration corresponding to the photon energies of 4.6 and 5.7 eV in the UV-visible region were observed at 206.6 x 10-13 and 294.3 x 10-13 esu, resp. Besides, the theor. χ(3) values were obtained at 50.58 x 10-13 and 20.37 x 10-13 esu by using M06-L level. Zn(II) complex could be an effective third-order NLO candidate material. In brief, the detailed theor. and exptl. structural, spectral and optical properties of the Zn(II) complex were presented comparatively. In addition to this study using Picolinic acid, there are many other studies that have used Picolinic acid(cas: 98-98-6Related Products of 98-98-6) was used in this study.

Picolinic acid(cas: 98-98-6) is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.Related Products of 98-98-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Product Details of 1539-42-0In 2020 ,《A 4,5-quinolimide-based fluorescent sensor for sequential detection of Cu2+ and cysteine in water and living cells with application in a memorized device》 appeared in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy. The author of the article were Zhang, Yu; Li, Lan; Wang, Jinping; Jia, Lihua; Yang, Rui; Guo, Xiangfeng. The article conveys some information:

A new 4,5-quinolimide-based fluorescent sensor BNC was synthesized and characterized. BNC showed single selectivity for Cu2+via the “”turn-off”” fluorescence among various common metal ions. After forming a 1:1 stoichiometric complex with Cu2+, the detection limit (LOD) of BNC for Cu2+ is 0.44μM. Subsequently, the in situ generated BNC-Cu2+ complex had been used for sensing Cys with the LOD of 1.5μM through the displacement strategy, resulting in the revivable emission of BNC. According to the “”off-on-off”” fluorescence cycle of BNC generated by the alternate addition of Cu2+ and Cys, a reversible memorized device with “”read-write-read-erase”” behavior was constructed at the mol. level. Furthermore, the recoveries of Cu2+ in lake water with BNC were at 95.0-105%. And sequential fluorescence imagings of BNC for Cu2+ and Cys were successfully applied in living yeast cells.Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Product Details of 1539-42-0) was used in this study.

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Product Details of 1539-42-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Synthesis and structural study of tris(2,6-diaminopyridinium) bis(oxalato)dioxidovanadate(V) 2.5-hydrate》 was written by Sehimi, Hiba; Akitsu, Takashiro; Zid, Mohamed Faouzi. Application In Synthesis of 2,6-DiaminopyridineThis research focused ontrisdiaminopyridinium bis oxalatodioxidovanadatehydrate crystal structure; 2,6-di­amino­pyridine; bis­(oxalato) complexes; crystal structure; dioxovanadate(V); vanadium. The article conveys some information:

Crystals of the title compound, (C5H8N3)3[VO2(C2O4)2]·2.5H2O, a mononuclear VV complex, were obtained by slow evaporation at room temperature of an aqueous solution containing vanadium pentoxide, oxalic acid and 2,6-diaminopyridine. The asym. unit contains one bis(oxalato)dioxovanadate(V) anionic complex, three 2,6-diaminopyridinium cations and two and a half uncoordinated water mols. The mononuclear vanadium(V) anions are connected to the organic cations and water mols. through a strong N-H···O and O-H···O hydrogen-bond network, consolidated by π-π stacking interactions, to form a three-dimensional structure. In the experiment, the researchers used many compounds, for example, 2,6-Diaminopyridine(cas: 141-86-6Application In Synthesis of 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Application In Synthesis of 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Impact of Pyridyl Moieties on the Inhibitory Properties of Prominent Acyclic Metal Chelators Against Metallo-β-Lactamase-Producing Enterobacteriaceae: Investigating the Molecular Basis of Acyclic Metal Chelators’ Activity》 were Sosibo, Sphelele C.; Somboro, Anou M.; Amoako, Daniel G.; Osei Sekyere, John; Bester, Linda A.; Ngila, Jane C.; Sun, Darren D.; Kumalo, Hezekiel M.. And the article was published in Microbial Drug Resistance (New Rochelle, NY, United States) in 2019. Computed Properties of C12H13N3 The author mentioned the following in the article:

Carbapenem-resistant Enterobacteriaceae (CREs)-mediated infections remain a huge public health concern. CREs produce enzymes such as metallo-β-lactamases (MBLs), which inactivate β-lactam antibiotics. Hence, developing efficient mols. capable of inhibiting these enzymes remains a way forward to overcoming this phenomenon. In this study, we demonstrate that pyridyl moieties favor the inhibitory activity of cyclic metal-chelating agents through in vitro screening, mol. modeling, and docking assays. Di-(2-picolyl) amine and tris-(2-picolyl) amine exhibited great efficacy against different types of MBLs and strong binding affinity for NDM-1, whereas 2-picolyl amine did not show activity at a concentration of 64 mg/L in combination with meropenem; it further showed the lowest binding affinity from computational mol. anal., commensurating with the in vitro screening assays. The findings revealed that the pyridyl group plays a vital role in the inhibitory activity of the tested mols. against CREs and should be exploited as potential MBL inhibitors. After reading the article, we found that the author used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Computed Properties of C12H13N3)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. Computed Properties of C12H13N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Chromogenic hydrazide Schiff base reagent: Spectrophotometric determination of CN- ion》 was published in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. These research results belong to Dey, Sunanda; Sen, Chandana; Sinha, Chittaranjan. Name: Picolinic acid The article mentions the following:

A Schiff base reagent, Picolinohydrazide-naphthol (HL), was used for trace level detection of toxic CN- selectively in presence of eighteen other anions (SCN-, OCN-, S2O2-3, HPO2-4, H2PO-4, I-, ClO-4, HSO-4, SO2-4, AsO3-4, NO-2, AsO-2, Cl-, F-, HF-2, NO-3, Br-, N-3) by visual color change, colorless to yellow, in DMSO/H2O (9:1, volume/volume) at pH, 7.2 (HEPES buffer) medium. The sensitivity of the probe shows that the limit of detection (LOD) is 7.08μM. The probable mechanism for the sensing behavior involves the deprotonation of naphthol-OH by CN- that was authenticated by 1H NMR titration and Mass spectra. The composition (1:1 mol ratio) is supported by Job’s plot and binding constant (Ka, 1.5 × 104 M-1) is reported by Benesi-Hildebrand plot. Also, a simple paper strip device is fabricated for the determination of CN- ion in water. DFT computation is carried out to explain the electronic spectral feature of the sensor.Picolinic acid(cas: 98-98-6Name: Picolinic acid) was used in this study.

Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Name: Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Fischer, Kim; Krahmer, Jan; Tuczek, Felix published an article in Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences. The title of the article was 《Chemically and Light-Driven Coordination-Induced Spin State Switching (CISSS) of a nonheme-iron complex》.Synthetic Route of C12H13N3 The author mentioned the following in the article:

The new Fe(II) complex [Fe(trident)(bmik)](ClO4)2 (1) (trident = bis(2-pyridylmethyl)benzylamine and bmik = bis(1-methylimidazole)ketone) exhibits a change of magnetic moment in dichloromethane (DCM) solution upon addition of pyridine which is attributed to the Coordination-Induced Spin State Switching effect (CISSS). By attaching a photoisomerizable azopyridine sidegroup to the tridentate ligand the complex [Fe(azpy-trident)(bmik)](ClO4)2 (2; azpy-trident = [N,N-bis(2-pyridylmethyl)]-3-(3-pyridylazo)benzylamine) is obtained. As detected by Evans NMR spectroscopy, 2 reversibly changes its magnetic moment in homogeneous solution upon photoirradiation which is attributed to intermol. Light-Driven Coordination-Induced Spin State Switching (LD-CISSS). Further support for this interpretation is inferred from concentration-dependent Evans NMR measurements. In the experimental materials used by the author, we found Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Synthetic Route of C12H13N3)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. Synthetic Route of C12H13N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Simultaneous determination of phenazopyridine HCl and trimethoprim in presence of phenazopyridine HCl impurity by univariate and multivariate spectrophotometric methods – Quantification of phenazopyridine HCl impurity by univariate methods》 was written by Soudi, Aya T.; Hussein, Ola G.; Elzanfaly, Eman S.; Zaazaa, Hala E.; Abdelkawy, Mohamed. Synthetic Route of C5H7N3 And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. The article conveys some information:

Three univariate and two multivariate spectrophotometric methods were developed and subsequently validated to determine phenazopyridine HCl (PHZ) and trimethoprim (TMP) in the presence of 2,6-Diaminopyridine (2,6-DAP). The first univariate method depends on direct determination of phenazopyridine by measuring its absorbance at 412 nm and performed in concentration range of 1.00-10.00μg/mL. Then the contribution of phenazopyridine is removed by dividing the mixture spectrum with PHZ divisor (5μg/mL) after that the constant is math. subtracted and finally the generated spectrum is multiplied with the PHZ divisor. These steps eliminate PHZ contribution and the recovered spectrum is that of TMP and 2,6-DAP only where different methods can be applied to determine TMP and 2,6-DAP through this binary mixture spectrum. The first method to determine both components depends on measuring both TMP and 2,6-DAP through their first derivative (1DD) spectra at 244.70 and 259.60 nm for TMP and 2,6-DAP, resp. with concentration ranges of 4.00-24.00μg/mL TMP and 4.00-26.00μg/mL 2,6-DAP. The second method depends on application of the isoabsorptive method which was used for TMP determination at its isoabsorptive point with 2,6-DAP at 242.64 nm with concentration range 1.00-20.00μg/mL for TMP. The developed univariate methods were successfully applied to determine PHZ, TMP and PHZ impurity (2,6-DAP). Two multivariate methods were applied for determination of PHZ and TMP in presence of 2,6-DAP namely, Principle Component Regression (PCR) and Partial Least Squares (PLS). The results of the two models show that simultaneous determination of PHZ and TMP in presence of PHZ impurity can be performed in the concentration ranges of 6.00-14.00μg/mL PHZ and 24.00-56.00μg/mL TMP. All the proposed methods were successfully applied to analyze PHZ and TMP in pharmaceutical formulations without interference from the dosage form additives and the results were statistically compared with the reported method.,. In the experimental materials used by the author, we found 2,6-Diaminopyridine(cas: 141-86-6Synthetic Route of C5H7N3)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Synthetic Route of C5H7N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Bhalla, Parul; Tomer, Nisha; Bhagat, Pooja; Malhotra, Rajesh published an article in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy. The title of the article was 《Chromone functionalized pyridine chemosensor for cupric ions detection》.Product Details of 141-86-6 The author mentioned the following in the article:

A new Schiff base 2-ethoxy-3-{[(6-{[(2-ethoxy-4-hydroxy-2H-chromen-3-yl)methylidene]amino}pyridine-2-yl)imino]methyl}-2H-chromen-4-ol (CD) was synthesized as a result of the condensation of 2,6-diaminopyridine and 3-formyl chromone in 1:2 M ratio and used for cupric ions detection and characterized through FTIR, HRMS and 1H NMR spectral techniques. The sensing capability of Schiff base for cupric ions as compared to other transition metal ions was examined by absorbance and emission studies. A considerable decrease in emission intensity appeared in Schiff base in the case of cupric ions while irrelevant changes were examined for the rest of the ions. The binding stoichiometry was obtained as 1:2 for CD: Cu2+ complex intended from the job′s plot which was confirmed through HRMS spectral technique. DFT calculations were carried for the confirmation of structural relationships and absorption-emission data. The Regression coefficient, Limit of detection, and Association constant were obtained as 98.7%, 1.2 x 10-6 M, and 3.26 x 104 M-1 resp. using Benesi-Hildebrand (B-H) equation. The sensing power of Schiff base CD to recognize cupric ions was unaltered by the addition of the rest of metal ions, which was authenticated through interference studies. Schiff base CD and its complex with cupric ions were found stable over an extensive time period as revealed by time-reliant studies. The data collected by pH studies revealed that the preferred pH range for detecting cupric ions by Schiff base CD was 6 to 11. The Schiff base was finally utilized for sensing cupric ions in a variety of spiked samples of water like canal water, tap water, groundwater, distilled water. In the experiment, the researchers used many compounds, for example, 2,6-Diaminopyridine(cas: 141-86-6Product Details of 141-86-6)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Product Details of 141-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Crystal structures of a series of bis(acetylacetonato)oxovanadium(IV) complexes containing N-donor pyridyl ligands》 was written by Rood, Jeffrey A.; Reehl, Steven R.; Jacoby, Kaitlyn A.; Oliver, Allen. Safety of 4-CyanopyridineThis research focused onvanadium complex crystal structure crystallization; bidentate ligands; cis/trans isomers; coordination compound; crystal structure; vanadium(IV). The article conveys some information:

Crystal structures for a series of bis(acetylacetonato)oxovanadium(IV) complexes containing N-donor pyridyl ligands are reported, namely, bis(acetylacetonato-κ2O,O′)oxido(pyridine-κN)vanadium(IV), [V(C5H7O2)2O(C5H5N)], 1, bis(acetylacetonato-κ2O,O′)oxido(pyridine-4-carbonitrile-κN)vanadium(IV), [V(C5H7O2)2O(C6H4N2)], 2, and bis(acetylacetonato-κ2O,O′)(4-methoxypyridine-κN)oxidovanadium(IV), [V(C5H7O2)2O(C6H7NO)], 3, Compounds 1-3 have the formulas VO(C5H7O2)2L, where L = pyridine (1), 4-cyano-pyridine (2), and 4-methoxypyridine (3). Compound 1 was previously reported [Meicheng et al. (1984). Kexue Tongbao, 29, 759-764 and DaSilva, Spiazzi, Bortolotto & Burrow (2007). Acta Crystallogr., E63, m2422] and redetermined here at cryogenic temperatures Compounds 1 and 2 as pyridine and 4-cyanopyridine adducts, resp., crystallize as distorted octahedral structures with the oxo and pyridyl ligands trans to one another. A crystallog. twofold axis runs through the O-V-N bonds. Compound 3 containing a 4-methoxypyridine ligand crystallizes as a distorted octahedral structure with the oxo and pyridyl ligands cis to one other, removing the twofold symmetry seen in the other complexes. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Safety of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Safety of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2018,Zeghouan, Ouahida; Dems, Mohamed AbdEsselem; Sellami, Seifeddine; Merazig, Hocine; Daran, Jean Claude published 《A strongly fluorescent NiII complex with 2-(2-hydroxyethyl)pyridine ligands: synthesis, characterization and theoretical analysis and comparison with a related polymeric Cu complex》.Acta Crystallographica, Section E: Crystallographic Communications published the findings.Category: pyridine-derivatives The information in the text is summarized as follows:

The synthesis and characterization of diaquabis 2-(2-hydroxyethyl)pyridine-κ2N,O nickel dinitrate, Ni C7H9NO2H2O2NO32, under ambient conditions is reported and compared with catena-poly bis 2-2-hydroxyethylpyridine-κ2N,O copper-μ-sulfato-κ2O:O’, CuC7H9NO2SO4n Zeghouan et al. 2016. Private communication refcode 1481676. CCDC, Cambridge, England. In the two complexes, the 2-(2-hydroxyethyl)pyridine ligands coordinate the metal ions through the N atom of the pyridine ring and the O atom of the hydroxy group, creating a chelate ring. The NiII or CuII ion lies on an inversion center and exhibits a slightly distorted MO4N2 octahedral coordination geometry, build up by O and N atoms from two 2-(2-hydroxyethyl)pyridine ligands and two water mols. or two O atoms belonging to sulfate anions. The sulfate anion bridges the CuII ions, forming a polymeric chain. The photoluminescence properties of these complexes have been studied on as-synthesized samples and reveal that both compounds display a strong blue-light emission with maxima around 497 nm. From DFT/TDDFT studies, the blue emission appears to be derived from the ligand-to-metal charge-transfer (LMCT) excited state. In addition, the IR spectroscopic properties and thermogravimetric behaviors of both complexes have been investigated. In the part of experimental materials, we found many familiar compounds, such as 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Category: pyridine-derivatives)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem