Day: October 13, 2022

《A novel multidentate pyridyl ligand: A turn-on fluorescent chemosensor for Hg2+ and its potential application in real sample analysis》 was written by Ngororabanga, Jean Marie Vianney; Moyo, Cyprian B.; Tshentu, Zenixole R.. Application In Synthesis of 2,6-Diaminopyridine And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. The article conveys some information:

A novel pyridyl-based ligand with multiple binding sites was developed as potential turn on fluorescent probe for mercuric ion. In comparison with other transition metal ions, the ligand displayed a significant optical selectivity and sensitivity for Hg2+ in aqueous solution with a remarkable fluorescence enhancement. The obtained spectroscopic response was related to the inhibition of the photo-chem. mechanism known as photo-induced electron transfer (PET) in the ligand and C=N isomerization by Hg2+ binding. A good linearity between fluorescence responses and Hg2+ concentration was obtained in the range 3.3 x 10-9 M-1.6 x 10-8 M and a nanomolar level limit of detection (LOD) (1.4 x 10-9 M ∼ 0.28 ppb) and limit of quantification (LOQ) (4.8 x 10-9 M ∼ 0.93 ppb) were obtained. Both LOD and LOQ values are very low compared to the reported permissible Hg2+ level in drinking water (2 ppb) by US Environmental Protection Agency (EPA). The possible binding mode between ligand and Hg2+ were determined using Job′s plot anal. and d. functional theory (DFT) calculations and a complex with 1:1 stoichiometric ratio was suggested. The response of the pyridyl ligand upon Hg2+ addition was noted to be fast without any time delay and reversible. The performance of the ligand at nanomolar level of Hg2+ and real sample application of the proposed method was investigated and satisfactory results were obtained. In the part of experimental materials, we found many familiar compounds, such as 2,6-Diaminopyridine(cas: 141-86-6Application In Synthesis of 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Application In Synthesis of 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Synthesis and spectroscopic study of some 3-nitropyridines》 were Youssef, Adel F.; Farag, Hassan H.; Youssef, H.. And the article was published in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 1977. Name: 2-Methyl-3-nitropyridine hydrochloride The author mentioned the following in the article:

6-Methyl-5-nitropyridine-2-carboxylic acid (I), and 3-(2-methyl-3-nitro-6-pyridyl)acrylic acid (II) were prepared The IR, mass and NMR spectra of 2,6-dimethyl-3-nitropyridine, 2-methyl-3-nitropyridine (III) and II were discussed. The structures of I and II were confirmed indirectly via conformation of the structure of their precursor III. II was a mixture of cis-(38%) and trans-(62%) isomers as revealed by its NMR. In the experiment, the researchers used 2-Methyl-3-nitropyridine hydrochloride(cas: 63585-69-3Name: 2-Methyl-3-nitropyridine hydrochloride)

2-Methyl-3-nitropyridine hydrochloride(cas: 63585-69-3) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Name: 2-Methyl-3-nitropyridine hydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《A cocrystal of L-ascorbic acid with picolinic acid: the role of O-H···O, N-H···O and C-H···O hydrogen bonds and L-ascorbic acid conformation in structure stabilization》 was written by Evtushenko, Diana N.; Arkhipov, Sergey G.; Fateev, Alexander V.; Izaak, Tatyana I.; Egorova, Lidia A.; Skorik, Nina A.; Vodyankina, Olga V.; Boldyreva, Elena V.. Category: pyridine-derivatives And the article was included in Acta Crystallographica, Section B: Structural Science, Crystal Engineering and Materials in 2020. The article conveys some information:

A new 1:1 cocrystal (L-Asc-Pic) of L-ascorbic acid (vitamin C) with picolinic acid was prepared as a powder and as single crystals. The crystal structure was solved and refined from single-crystal X-ray diffraction (SCXRD) data collected at 293 (2) and 100 (2) K. The samples of the L-Asc-Pic cocrystal were characterized by elemental (HCNS) anal. and titrimetric methods, TG/DTG/DSC, and IR and Raman spectroscopy. The asym. unit comprises a picolinic acid zwitterion and an L-ascorbic acid mol. The stabilization energy of intermol. interactions involving hydrogen bonds, the vibrational spectrum and the energies of the frontier MOs were calculated using the GAUSSIAN09 and the CrystalExplorer17 programs. The charge distribution on the atoms of the L-Asc-Pic cocrystal, L-ascorbic acid itself and its 12 known cocrystals (structures from Version 5.40 of the Cambridge Structural Database) were calculated by the methods of Mulliken, Voronoi and Hirshfeld charge analyses (ADF) at the bp86/TZ2P+ level of theory. The total effective charges and conformations of the L-ascorbic acid mols. in the new and previously reported cocrystals were compared with those of the two symmetry-independent mols. in the crystals of L-ascorbic acid. A correlation between mol. conformation and its effective charge is discussed. In the experiment, the researchers used many compounds, for example, Picolinic acid(cas: 98-98-6Category: pyridine-derivatives)

Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem