Ismail, Hani K’s team published research in Journal of Electroanalytical Chemistry in 2020-11-01 | 93-60-7

Journal of Electroanalytical Chemistry published new progress about Chronoamperometry. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Related Products of 93-60-7.

Ismail, Hani K. published the artcile< Electrodeposition of a mirror zinc coating from a choline chloride-ethylene glycol-based deep eutectic solvent modified with methyl nicotinate>, Related Products of 93-60-7, the main research area is electrodeposition zinc choline chloride ethylene glycol solvet; deep eutectic solvent modified methyl nicotinate.

A number of studies have reported the effects of additives on metal coatings electrochem. deposited from deep eutectic solvents (DESs). However, no previous study has studied the influences of Me nicotinate (MN) as an additive on the electrodeposition of Zn on a Cu substrate from a DES. The results of this study show that MN significantly develops the Zn deposition in this system compared to the corresponding system in its absence. This is the 1st study to date to show that a mirror Zn coating can be obtained on a Cu substrate using such a mechanism. Various electrochem. methods such as cyclic voltammetry, chronocoulometry, and chronoamperometry were used to understand the electrochem. properties of Zn electrolytes in the absence and presence of MN. These experiments found that the redox reaction currents decline when the additive was included in the Zn electrolyte, and that Zn deposition followed an instantaneous nucleation mechanism in the absence of the additive while in its presence the mechanism was closer to that of progressive growth. Further, the current efficiency decreased from 98.99% in the absence of additive to ∼82% as a result of including the additive in the Zn plating bath, according to electrochem. quartz crystal microbalance (EQCM) data. The resultant roughness, thickness and surface morphol. of the deposited Zn were characterized using at. force microscopy, SEM, and x-ray diffraction, indicating that Me nicotinate, as an additive, functions as a highly influential brightener that gave highly homogeneous and flat Zn deposits.

Journal of Electroanalytical Chemistry published new progress about Chronoamperometry. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Related Products of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mathuri, Ashis’s team published research in Organic & Biomolecular Chemistry in 2021 | 2127-03-9

Organic & Biomolecular Chemistry published new progress about Aromatic compounds, disulfides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Synthetic Route of 2127-03-9.

Mathuri, Ashis; Pramanik, Milan; Parida, Amarchand; Mal, Prasenjit published the artcile< Disulfide metathesis via sulfur···iodine interaction and photoswitchability>, Synthetic Route of 2127-03-9, the main research area is unsym disulfide preparation; sym disulfide cross metathesis reaction photoswitchable.

Herein, the synthesis of unsym. diaryl disulfides RSSR1 (R = 2-MeC6H4, furan-2-ylmethyl, pyridin-2-yl, etc., R1 = CH2CHMe2, cyclohexyl, 4-ClC6H4, etc.) from two sym. disulfides RSSR and R1SSR1 via a cross-metathesis reaction which was controlled by a weak sulfur···iodine (S···I) interaction is reported. The unsym. disulfides were stable in acetonitrile solution in the presence of N-iodosuccinimide (NIS), and were found to be reversibly photoswitchable to the sym. disulfides under visible light irradiation

Organic & Biomolecular Chemistry published new progress about Aromatic compounds, disulfides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Synthetic Route of 2127-03-9.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhou, Pengpeng’s team published research in Journal of Chemical Research in 2020-07-31 | 2127-03-9

Journal of Chemical Research published new progress about Cyanation. 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Electric Literature of 2127-03-9.

Zhou, Pengpeng; Chen, Chuan; Li, Shubai published the artcile< Selectfluor-initiated cyanation of disulfides to thiocyanates>, Electric Literature of 2127-03-9, the main research area is disulfide trimethylsilyl cyanide Selectfluor promoter cyanation green chem; thiocyanate preparation.

A Selectfluor-initiated cyanation of disulfides to thiocyanates was developed. In this process, Selectfluor was employed as the oxidant and trimethylsilyl cyanide was used as the cyanation reagent. It provides an eco-friendly and simple way to synthesize the thiocyanates.

Journal of Chemical Research published new progress about Cyanation. 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Electric Literature of 2127-03-9.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hussain, Afzal’s team published research in Scientific Reports in 2019-12-31 | 366-18-7

Scientific Reports published new progress about Analgesics. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Electric Literature of 366-18-7.

Hussain, Afzal; AlAjmi, Mohamed Fahad; Rehman, Tabish Md.; Amir, Samira; Husain, Fohad Mabood; Alsalme, Ali; Siddiqui, Maqsood Ahmad; AlKhedhairy, Abdulaziz A.; Khan, Rais Ahmad published the artcile< Copper(II) complexes as potential anticancer and Nonsteroidal anti-inflammatory agents: In vitro and in vivo studies>, Electric Literature of 366-18-7, the main research area is copper complex anticancer nonsteroidal antiinflammatory agent breast cancer.

Copper-based compounds are promising entities for target-specific next-generation anticancer and NSAIDS therapeutics. In lieu of this, benzimidazole scaffold plays an important role, because of their wide variety of potential functionalizations and coordination modes. Herein, we report three copper complexes 1-3 with benzimidazole-derived scaffolds, a biocompatible mol., and secondary ligands viz, 1-10-phenanthroline and 2,2′-bipyridyl. All the copper complexes have been designed, synthesized and adequately characterized using various spectroscopic techniques. In-vitro, human serum albumin (HSA) binding was also carried out using fluorescence technique and in-silico mol. modeling studies, which exhibited significant binding affinities of the complexes with HSA. Furthermore, copper complexes 1-3 were tested for biol. studies, i.e., anticancer as well as NSAIDS. In vitro cytotoxicity results were carried out on cultured MCF-7 cell lines. To get the insight over the mechanism of action, GSH depletion and change in lipid peroxidation were tested and thus confirmed the role of ROS generation, responsible for the cytotoxicity of the complexes 1-3. Moreover, the copper complexes 1-3 were tested for potential to act as NSAIDS on albino rats and mice in animal studies in-vivo. Addnl., we also predicted the mechanism of action of the copper complexes 1-3 using mol. modeling studies with COX-2 inhibitor.

Scientific Reports published new progress about Analgesics. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Electric Literature of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dalal, Anuj’s team published research in Journal of Fluorescence in 2022-05-31 | 366-18-7

Journal of Fluorescence published new progress about Cyclic voltammetry. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application In Synthesis of 366-18-7.

Dalal, Anuj; Nehra, Kapeesha; Hooda, Anjli; Singh, Sitender; Singh, Devender; Kumar, Sumit published the artcile< Synthesis, Optoelectronic and Photoluminescent Characterizations of Green Luminous Heteroleptic Ternary Terbium Complexes>, Application In Synthesis of 366-18-7, the main research area is green luminous heteroleptic ternary terbium complexe optoelectronic photoluminescence property; 2,2’-Bipyridine; Color purity; Fluorescence; Tauc’s relation; Ternary terbium complexes.

This article presents four ternary terbium complexes based on fluorinated 2-thenoyltrifluoroacetone (TTFA) and N donor bidentate neutral ligands. The prepared complexes were examined by elemental study, electrochem. anal., spectroscopically and thermo-gravimetrically. Spectral anal. shows the bonding of Tb3+ ion with oxygen and nitrogen atom of diketone and neutral ligand resp. Upon excitation in UV region, synthesized terbium complexes show luminescence in green region of electromagnetic spectrum. Photoluminescence emission spectra of complexes do not show any ligand based peak suggesting the effective transferal of energy from ligand to metal ion. Green emanation by terbium complexes is owing to intense peak ∼547 nm (5D4 → 7F5). The outcome of emission data and CIE coordinates correlate with each other and affirms the utility of green luminous complexes as potential emissive material for optoelectronic gadgets applied in lighting system.

Journal of Fluorescence published new progress about Cyclic voltammetry. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Application In Synthesis of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dang, Yanfeng’s team published research in Journal of the American Chemical Society in 2014-01-22 | 1416819-91-4

Journal of the American Chemical Society published new progress about Alkenyl alcohols Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 1416819-91-4 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, Related Products of 1416819-91-4.

Dang, Yanfeng; Qu, Shuanglin; Wang, Zhi-Xiang; Wang, Xiaotai published the artcile< A Computational Mechanistic Study of an Unprecedented Heck-Type Relay Reaction: Insight into the Origins of Regio- and Enantioselectivities>, Related Products of 1416819-91-4, the main research area is Heck type relay reaction mechanism regioselectivity enantioselectivity.

D. functional theory (DFT) calculations (B3LYP and M06) have been utilized to study a newly reported Heck-type reaction that uses an allylic or alkenyl alc. as substrate and palladium as catalyst in the form of a chelate with a chiral pyridine oxazoline (PyrOx) ligand. The reaction not only controls the regio- and enantioselectivities of arylation of the C=C bond, but also forms the carbonyl functionality up to four bonds away from the aryl substituent via tandem C=C bond migration and enol-to-keto conversion. Computations performed on representative reaction systems allow us to propose a detailed mechanism with several key steps. Initial oxidation of palladium(0) by aryldiazonium generates active arylpalladium(II) species that bind the C=C bond of an allylic or alkenyl alc. The activated C=C bond inserts into the palladium-aryl moiety to attain aryl substitution and a chiral carbon center, and the resulting complex undergoes β-hydride elimination to give a new C=C bond that can repeat the insertion/elimination process to move down the carbon chain to form an enol that tautomerizes to a highly stable carbonyl final product. The calculations reveal that the C=C bond migratory insertion step determines both the regioselectivity and the enantioselectivity of arylation, with the former arising mainly from the electronic effect of the hydroxyl group on the charge distribution over the C=C bond and the latter originating from a combination of steric repulsion, trans influence, and C-H/π dispersion interactions.

Journal of the American Chemical Society published new progress about Alkenyl alcohols Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 1416819-91-4 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, Related Products of 1416819-91-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mangala Prasad, Vidya’s team published research in Cell (Cambridge, MA, United States) in 2022-02-17 | 2127-03-9

Cell (Cambridge, MA, United States) published new progress about Antibodies and Immunoglobulins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Computed Properties of 2127-03-9.

Mangala Prasad, Vidya; Leaman, Daniel P.; Lovendahl, Klaus N.; Croft, Jacob T.; Benhaim, Mark A.; Hodge, Edgar A.; Zwick, Michael B.; Lee, Kelly K. published the artcile< Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice>, Computed Properties of 2127-03-9, the main research area is HIV1 virions structural variation Env Gag glycosylation gp120; Gag-Env interaction; HIV Env glycoprotein; HIV assembly; broadly neutralizing antibody; cryo-electron microscopy; cryo-electron tomography; hydrogen/deuterium-exchange mass spectrometry; sub-tomogram averaging; vaccine design; virus structure.

HIV-1 Env mediates viral entry into host cells and is the sole target for neutralizing antibodies. However, Env structure and organization in its native virion context has eluded detailed characterization. Here, we used cryo-electron tomog. to analyze Env in mature and immature HIV-1 particles. Immature particles showed distinct Env positioning relative to the underlying Gag lattice, providing insights into long-standing questions about Env incorporation. A 9.1-Å sub-tomogram-averaged reconstruction of virion-bound Env in conjunction with structural mass spectrometry revealed unexpected features, including a variable central core of the gp41 subunit, heterogeneous glycosylation between protomers, and a flexible stalk that allows Env tilting and variable exposure of neutralizing epitopes. Together, our results provide an integrative understanding of HIV assembly and structural variation in Env antigen presentation.

Cell (Cambridge, MA, United States) published new progress about Antibodies and Immunoglobulins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Computed Properties of 2127-03-9.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Steyer, Daniel J’s team published research in Analytical Chemistry (Washington, DC, United States) in 2019-05-21 | 350-03-8

Analytical Chemistry (Washington, DC, United States) published new progress about Droplet microfluidics. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.

Steyer, Daniel J.; Kennedy, Robert T. published the artcile< High-Throughput Nanoelectrospray Ionization-Mass Spectrometry Analysis of Microfluidic Droplet Samples>, Formula: C7H7NO, the main research area is high throughput nanoelectrospray mass spectrometry droplet microfluidics.

Droplet microfluidics enables high-throughput manipulation of fL-μL volume samples. Methods implemented for the chem. anal. of microfluidic droplets have been limited in scope, leaving some applications of droplet microfluidics difficult to perform or out of reach entirely. Nanoelectrospray ionization-mass spectrometry (nESI-MS) is an attractive approach for droplet anal., because it allows rapid, label-free, information-rich anal. with high mass sensitivity and resistance to matrix effects. Previous proof-of-concept systems for the nESI-MS anal. of droplets have been limited by the microfluidics used so that stable, long-term operation needed for high-throughput applications has not been demonstrated. The authors describe a platform for the stable anal. of microfluidic droplet samples by nESI-MS. Continuous infusion of droplets to an nESI emitter was demonstrated for as long as 2.5 h, corresponding to anal. of over 20 000 samples. Stable signal was observed for droplets as small as 65 pL and for throughputs as high as 10 droplets/s. A linear-concentration-based response and sample-to-sample carryover of <3% were also shown. The system is demonstrated for measuring products of in-droplet enzymic reactions. Analytical Chemistry (Washington, DC, United States) published new progress about Droplet microfluidics. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Formula: C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Devi, Lalita’s team published research in Chemical Communications (Cambridge, United Kingdom) in 2022 | 93-60-7

Chemical Communications (Cambridge, United Kingdom) published new progress about [3+2] Cycloaddition reaction. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Name: 3-(Methoxycarbonyl)pyridine.

Devi, Lalita; Kumar, Prashant; Kant, Ruchir; Rastogi, Namrata published the artcile< Exploiting the umpolung reactivity of diazo groups: direct access to triazolyl-azaarenes from azaarenes>, Name: 3-(Methoxycarbonyl)pyridine, the main research area is triazolyl isoquinoline pyridine phenanthridine preparation; azaarene diazo iodonium triflate tandem electrophilic substitution dipolar cycloaddition.

The present work documents electrophilic substitution of azaarenes, mainly isoquinolines, with hypervalent iodine diazo reagents (HIDR) followed by formal [3+2]-dipolar cycloaddition in a tandem fashion. Other azaarenes viz. pyridines and phenanthridines too could be successfully used in the reaction. The methodol. capitalizes on the umpolung nature of α-aryliodonio diazo compounds for installing a nucleophile, i.e. azaarene, at their α-position. Subsequent ylide formation and intramol. 1,5-cyclization furnished 4,3-fused 1,2,4-triazolyl-azaarenes in good yields. The reaction is notable for its mild conditions, operational simplicity and fairly general scope.

Chemical Communications (Cambridge, United Kingdom) published new progress about [3+2] Cycloaddition reaction. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Name: 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mhanna, Ramona’s team published research in Nanoscale in 2019 | 123-03-5

Nanoscale published new progress about Aggregation. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride.

Mhanna, Ramona; Lee, Jonghun; Narayanan, Suresh; Reich, Daniel H.; Leheny, Robert L. published the artcile< Phase-dependent shear-induced order of nanorods in isotropic and nematic wormlike micelle solutions>, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride, the main research area is gold nanorod hexagonal wormlike micelle solution.

Small angle X-ray scattering with in situ shear was employed to study the assembly and ordering of dispersions of gold nanorods within wormlike micelle solutions formed by the surfactant cetylpyridinium chloride (CPyCl) and counter-ion sodium salicylate (NaSal). Above a threshold CPyCl concentration but below the isotropic-to-nematic transition of the micelles, the nanorods self-assembled under quiescent conditions into isotropically oriented domains with hexagonal order. Under steady shear at rates between 0.5 and 7.5 s-1, the nanorod assemblies acquired macroscopic orientational order in which the hexagonal planes were coincident with the flow-vorticity plane. The nanorods could be re-dispersed by strong shear but re-assembled following cessation of the shear. In the nematic phase of the micelles at higher surfactant concentration, the nanorods did not acquire hexagonal order but instead formed smectic-like layers in the gradient-vorticity plane under shear. Finally, at still higher surfactant concentration, where the micelles form a hexagonal phase, the nanorods showed no translational ordering but did acquire nematic-like order under shear due to alignment in the flow. Depletion forces mediated by the wormlike micelles are identified as the driving mechanism for this sequence of nanorod ordering behaviors, suggesting a novel mechanism for controlled, reconfigurable assembly of nanoparticles in solution

Nanoscale published new progress about Aggregation. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Recommanded Product: 1-Hexadecylpyridin-1-ium chloride.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem