Day: October 21, 2022

Liu, Guo Cheng; Li, Yan; Chi, Jie; Xu, Na; Wang, Xiu Li; Lin, Hong Yan; Chen, Yong Qiang published the artcile< Multi-functional fluorescent responses of cobalt complexes derived from functionalized amide-bridged ligand>, Quality Control of 3731-53-1, the main research area is cobalt methylenepyridinylnaphthalenedicarboxamide dicarboxylate coordination polymer preparation fluorescent indicator; crystal structure cobalt methylenepyridinylnaphthalenedicarboxamide dicarboxylate coordination polymer.

Multi-functional fluorescent detection for inorganic pollutants and biol. protein is important but challenging. Five multi-functional luminescent coordination polymers (LCPs), [Co2(L)2(PDA)2]·H2O (1), [Co(L)(TPD)(H2O)2]·8H2O (2), [Co(L)(1,3-BDC)]·2H2O (3), [Co(L)(MIP)]·H2O (4) and [Co3(L)3(HIPA)3] (5) [H2PDA = 1,3-phenylenediacetic acid, H2TPD = 2,5-thiophenedicarboxylic acid, 1,3-H2BDC = 1,3-benzenedicarboxylic acid, H2MIP = 5-methylisophthalic acid and H2HIPA = 5-hydroxyisophthalic acid] were successfully synthesized from a naphthalene-dicarboxamide [N,N’-bis(4-methylenepyridin-4-yl)-1,4-naphthalene dicarboxamide (L)] with multi-functional spacers. 1 And 2 show 4-c sql networks. 3-5 display mab, pcu and hxg 3-dimensional frameworks, resp. The title complexes exhibit multi-functional fluorescent responses towards metal ion (Fe3+), anions (CrO42-, Cr2O72- and MnO4-) and biol. protein (bovine serum albumin).

Dyes and Pigments published new progress about Bovine serum albumin Role: ANT (Analyte), ANST (Analytical Study). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Quality Control of 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Peng, Ling; Yao, Jing-Wen; Wang, Mei; Wang, Lin-Ye; Huang, Xiao-Lan; Wei, Xin-Feng; Ma, Dong-Ge; Cao, Yong; Zhu, Xu-Hui published the artcile< Efficient soluble deep blue electroluminescent dianthracenylphenylene emitters with CIE y (y ≤ 0.08) based on triplet-triplet annihilation>, Formula: C11H16BNO2, the main research area is deep blue electroluminescent dianthracenylphenylene emitter triplet annihilation.

It has been challenging to develop deep blue organic mol. fluorescent emitters with CIE y (y ≤ 0.08) based on triplet-triplet annihilation (TTA). Here, we report facilely available dianthracenylphenylene-based emitters, which have a 3,5-di(4-t-butylphenyl)phenyl moiety at the one end and 4-cyanophenyl or 3-pyridyl at the other end, resp. Both fluorophores show a high glass transition temperature of over 220°C with a thermal decomposition temperature of over 430°C at an initial weight loss of 1%. The preliminary characterizations of the organic light-emitting diodes (OLEDs) that utilized these nondoped emitters provided high EQEs of 4.6%-5.9% with CIE coordinates (0.15, 0.07-0.08). The anal. of the EL transient decay revealed that TTA contributed to the observed performance. The results show that the new emitters are attractive as a potential TTA-based host to afford stable deep blue fluorescent OLEDs.

Science Bulletin published new progress about Electric current-potential relationship. 329214-79-1 belongs to class pyridine-derivatives, and the molecular formula is C11H16BNO2, Formula: C11H16BNO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nallagonda, Rajender; Karimov, Rashad R. published the artcile< Copper-Catalyzed Regio- and Diastereoselective Additions of Boron-Stabilized Carbanions to Heteroarenium Salts: Synthesis of Azaheterocycles Containing Contiguous Stereocenters>, Name: 3-(Trifluoromethyl)pyridine, the main research area is nonaromatic nitrogen heterocycle preparation diastereoselective addition boron carbanion heteroarenium.

Nucleophilic addition of diborylalkyl reagents to N-alkyl or N-acylpyridinium and related heteroarenium salts has been developed as a key step for the synthesis of nonaromatic nitrogen heterocycles that contain contiguous stereogenic centers. Derivatization of the dihydropyridine products for the synthesis of tetrahydropyridines and piperidines have also been described.

ACS Catalysis published new progress about Boranes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (alkyl). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Name: 3-(Trifluoromethyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gao, Jian; Zhu, Yafeng; Liu, Wenqi; Jiang, Suyu; Zhang, Jie; Ma, Wei published the artcile< Hydrogen Bonds in Disulfonic-Functionalized Acid Ionic Liquids for Efficient Biodiesel Synthesis>, Reference of 21876-43-7, the main research area is biodiesel synthesis ionic liquid catalyst hydrogen bond.

Regulating the states of hydrogen bonds in ionic liquids (ILs) is an effective way to improve their catalytic performance. In this paper, disulfonic-functionalized acidic ionic liquids (DSFAILs) were synthesized successfully, including novel SO3H-functionalized binuclear IL (bis[3-(CH2)3SO3H-1-(CH2)2-Im][HSO4]2). For the biodiesel synthesis, compared with the traditional ILs catalysts, DSFAILs bis[(3-(CH2)3SO3H-1-(CH2)2-Im][HSO4]2, [Im(N (CH2)3SO3H)2][HSO4]) had higher catalytic activity even under mild reaction conditions. Using the d. functional theory (DFT) method, the role of hydrogen bonds in different SO3H-functionalized acidic ionic liquids (SFAILs) was explored. The forms of hydrogen bonds existing in different ILs directly determine their acidity. It suggested that the forming status of the active sites (hydrogen bonds) were diverse in different SFAILs. Also, deep ionization of the hydrogen atoms from the cation-anion strong interaction could increase the acidity and catalytic performance of SFAILs. From this, the structure-activity relationship between the SFAILs structures and the catalytic activity of Me oleate synthesis was proposed. Besides, the exptl. results also showed that bis[3-(CH2)3SO3H-1-(CH2)2-Im][HSO4]2 catalyst had a high catalytic activity to obtain Me oleate and the catalyst could be separated easily owing to its larger mol. weight However, [Im(N(CH2)3SO3H)2][HSO4] had a stronger acidity and a lower steric hindrance and thus a higher catalytic activity and was the optimal catalyst for the Me oleate synthesis. In the presence of a small amount of catalyst (6 wt %) and at low reaction temperature (353 K), the Me oleate yield could reach up to 93%. After six recycles of the catalyst, the Me oleate yield remained at 90%.

ACS Omega published new progress about Acidity. 21876-43-7 belongs to class pyridine-derivatives, and the molecular formula is C9H13NO3S, Reference of 21876-43-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Jiacheng; Siang Tan, Suan; Kyne, Sara Helen; Chan, Philip Wai Hong published the artcile< Minisci-Type Alkylation of N-Heteroarenes by N-(Acyloxy)phthalimide Esters Mediated by a Hantzsch Ester and Blue LED Light>, Safety of 3-(Trifluoromethyl)pyridine, the main research area is alkylated quinoline preparation; quinoline acyloxy phthalimide ester Minisci type alkylation HE mediated; isoquinoline alkylated preparation; acyloxy phthalimide ester isoquinoline Minisci type alkylation HE mediated; pyridine alkylated preparation; phthalimide ester acyloxy pyridine Minisci type alkylation HE mediated.

A synthetic method that enabled the Hantzsch ester (HE)-mediated Minisci-type C2-alkylation of quinolines, isoquinolines and pyridines by N-(acyloxy)phthalimide esters (NHPI) to afford alkylated N-heterocyclic products, e.g., I, under blue LED (light emitting diode) light (456 nm) was described. Achieved under mild reaction conditions at room temperature, the metal-free synthetic protocol was shown to be applicable to primary, secondary and tertiary NHPIs to give the alkylated N-heterocyclic products in yields of 21-99%. On introducing a chiral phosphoric acid, an asym. version of the reaction was also realized and provided product enantiomeric excess (ee) values of 53-99%.

Advanced Synthesis & Catalysis published new progress about Alkylation. 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Safety of 3-(Trifluoromethyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Jespersen, Daniel; Keen, Brockton; Day, Jon I.; Singh, Anuradha; Briles, Justin; Mullins, Duncan; Weaver, Jimmie D. published the artcile< Solubility of iridium and ruthenium organometallic photoredox catalysts>, HPLC of Formula: 370878-69-6, the main research area is solubility iridium ruthenium photoredox catalyst; Photocatalysis; heteroleptic; homoleptic; iridium; photocatalyst; photoredox; ruthenium; saturation; solubility; solvent.

Despite the exponential growth of the field of photocatalysis, for reasons that are not entirely clear, these precious photocatalysts are often used in the literature at loadings that exceed their maximum solubility On an industrial scale, the quantity of any precious-metal catalyst can be a substantial financial burden or a sourcing issue, not to mention concerns as to the ecol. and earth abundance of these catalysts. We believe that inattention to solubility has made these reactions appear less efficient than they actually are because much of the photocatalyst remains undissolved. Therefore, the maximum solubilities of iridium- and ruthenium-centered photocatalysts in industrially relevant solvents have been systematically identified. Furthermore, a literature photocatalytic reaction that our results suggested was beyond the maximum solubility has been revisited with interesting results.

Organic Process Research & Development published new progress about Photochemical redox reaction catalysts. 370878-69-6 belongs to class pyridine-derivatives, and the molecular formula is C33H21F3IrN3, HPLC of Formula: 370878-69-6.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ouchi, Hitoshi; Asahina, Aya; Asakawa, Tomohiro; Inai, Makoto; Hamashima, Yoshitaka; Kan, Toshiyuki published the artcile< Practical Total Syntheses of Acromelic Acids A and B>, Computed Properties of 777931-67-6, the main research area is acromelic acid A B total synthesis; asym conjugate addition intramol reductive amination epimerization.

Practical total syntheses of acromelic acids A (I) and B (II), which have potent neuro-excitatory activity, were accomplished in 13 (36% total yield) and 17 steps (6.9% total yield), resp., from 2,6-dichloropyridine. Regioselective transformation of sym. 2,6-dichloropyridine provided nitroalkenes III and IV. The pyrrolidine ring was efficiently constructed by Ni-catalyzed asym. conjugate addition followed by intramol. reductive amination.

Organic Letters published new progress about Alkaloids Role: SPN (Synthetic Preparation), PREP (Preparation). 777931-67-6 belongs to class pyridine-derivatives, and the molecular formula is C6H5BrClNO, Computed Properties of 777931-67-6.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sanchez Delgado, Giset Y.; Ferreira, Frederico Henrique do C.; Paschoal, Diego F. S.; Dos Santos, Helio F. published the artcile< The role of tridentate ligands on the redox stability of anticancer gold(III) complexes>, Reference of 366-18-7, the main research area is Chelating effect; DFT; Gold(III) complexes; Redox stability; VT-HAA; VT-HXAA.

Gold(III) complexes are promising compounds for cancer chemotherapy, whose action depends on their redox stability. In this context, the choice of ligands is crucial to adjust their reactivity and biol. response. The present study addressed the effect of the gold coordination sphere on the reduction potential (Eo) for ten gold(III) complexes containing five or six-membered rings tridentate ligands – [AuIII(trident)Cl]3+n (trident = NN̂N̂, CN̂N̂, CĈN̂, CN̂Ĉ, and NĈN̂). The calculated Eo covered a broad range of 2500 mV with the most stable complexes containing two Au-C bonds (Eo = -1.85 V for [AuIII(CĈN̂)Cl] – f). For complexes with one Au-C bond, the NĈN̂ ligands stabilize the gold(III) complex more efficiently than NN̂Ĉ; however, the inclusion of the non-innocent ligand bipy (2,2′-bipyridine) in NN̂ portion provides an extra stabilization effect. Among the derivatives with one Au-C bond, [AuIII(NN̂Ĉ)Cl]+ (NN̂ = bipy) (a) showed Eo = -1.20 V. For the complexes with NN̂N̂ ligands, Eo was pos. and almost constant (+0.60 V). Furthermore, the kinetics for ligand exchange reactions (Cl-/H2O, H2O/Cys and Cl-/Cys) were monitored for the most stable compounds and the energy profiles compared to the reduction pathways.

Journal of Inorganic Biochemistry published new progress about 366-18-7. 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Reference of 366-18-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mahmoudi, Maedeh; Bayat, Amir-Hossein; Boroujeni, Mahdi Eskandarian; Abdollahifar, Mohammad Amin; Ebrahimi, Vahid; Danyali, Samira; Heidari, Mohammad Hassan; Aliaghaei, Abbas published the artcile< Curcumin protects purkinje neurons, ameliorates motor function and reduces cerebellar atrophy in rat model of cerebellar ataxia induced by 3-AP>, Recommanded Product: 1-(Pyridin-3-yl)ethanone, the main research area is cerebellar ataxia purkinje neuron curcumin motor function; 3-Acethylpyridine; Cerebellar ataxia; Curcumin; Neuroprotection; Purkinje cells.

Cerebellar ataxias comprise a group of terminal illnesses with ataxia as the main symptom. Curcumin as a yellow polyphenol was extracted from the rhizome of Curcuma longa. Owing to its antioxidant, anti-inflammatory, anti-fibrotic and anti-tumor features, curcumin is considered as a potential therapeutic agent. In this study, we aim to investigate the neuroprotective effects of oral administration of curcumin on a rat model of cerebellar ataxia induced by neurotoxin 3-acetylpyridine. The animals were randomly separated into three groups (control, 3-acetylpyridine, and curcumin + 3-acetylpyridine). Next, motor performance and muscle electromyog. activity were assessed. Then, in the mol. part of the study, the anti-apoptotic role of curcumin in cerebellar ataxia and its relationship to protection of Purkinje cells were investigated. Curcumin treatment improved motor coordination and muscular activity, reduced cleaved caspase-3, and increased glutathione level in 3-AP-lesioned rats as well as total volumes of cerebellar granular and mol. layers.the present study implies that curcumin might have neuroprotective effects to counteract neurotoxicity of 3-AP-induced ataxia.

Journal of Chemical Neuroanatomy published new progress about Electromyography. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Recommanded Product: 1-(Pyridin-3-yl)ethanone.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nallagonda, Rajender; Karimov, Rashad R. published the artcile< Copper-Catalyzed Regio- and Diastereoselective Additions of Boron-Stabilized Carbanions to Heteroarenium Salts: Synthesis of Azaheterocycles Containing Contiguous Stereocenters>, Recommanded Product: 3-(Methoxycarbonyl)pyridine, the main research area is nonaromatic nitrogen heterocycle preparation diastereoselective addition boron carbanion heteroarenium.

Nucleophilic addition of diborylalkyl reagents to N-alkyl or N-acylpyridinium and related heteroarenium salts has been developed as a key step for the synthesis of nonaromatic nitrogen heterocycles that contain contiguous stereogenic centers. Derivatization of the dihydropyridine products for the synthesis of tetrahydropyridines and piperidines have also been described.

ACS Catalysis published new progress about Boranes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (alkyl). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Recommanded Product: 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem