Day: October 28, 2022

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Application In Synthesis of 5315-25-3.

Wang, Jinglan;Chen, Hongyun;Xu, Shengxian;Su, Qingzhi;Zhao, Feng;He, Haifeng research published 《 Highly effective luminescence stemmed from thermally activated delayed fluorescence (TADF) and phosphorescence for new four-coordinate copper(I) complexes containing N-heterocyclic carbene (NHC) ligands》, the research content is summarized as follows. The two four-coordinate N-heterocyclic carbene (NHC) copper(I) complexes, [Cu(Ph-BenIm-methylPy)(POP)]PF₆ (1), and [Cu(Ph-Im-methylPy)(POP)]PF₆ (2), Ph-BenIm-methylPy = 3-benzyl-1-(6-methyl-pyridin-2-yl)-1H-benzimidazolylidene, Ph-Im-methylPy = 3-benzyl-1-(6-methyl-pyridin-2-yl)-1H-imidazolylidene, POP = bis[2-(diphenylphosphino)phenyl] ether have been synthesized and characterized. Those complexes exhibit blue to green emission with very high quantum yields and long excited-state lifetimes. The exptl. results reveal that the origin of emissive state at room temperature occurs from the combination of TADF and phosphorescence in which phosphorescence predominates TADF, and the corresponding emissive mechanisms were discussed. To the best of our knowledge, the combined emissions with high quantum yield close to ca. 100% have not been previously reported in this library of the four-coordinate NHC-Cu(I) complexes.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Application In Synthesis of 5315-25-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Category: pyridine-derivatives.

Wang, Jinglan;Chai, Chaoyang;Xu, Shengxian;Zhao, Feng;Xia, Hongying;Wang, Yibo research published 《 Modulation of photophysical properties of copper(I) complexes containing pyridyl-imidazole (PyIm) ligands functionalized by naphthyl, phenanthryl, and anthryl groups》, the research content is summarized as follows. A series of Cu(I) pyridyl-imidazole (PyIm) complexes with different aryl groups (Ar = naphthalene (P2), phenanthrene (P3), and anthracene (P4)) attached on the pyridyl ring were synthesized and characterized. The influence of these organic chromophore groups on the photophys. properties of the resulting complexes is investigated. Complexes P2–P4 show stronger light harvesting efficiencies in the visible region compared with the parent complex P1. The emitting state of complex P1 originates from the ³MLCT state with some ³LLCT character, while complexes P2 and P3 predominantly exhibit the ³LLCT character. For complex P4, the triplet emitting state is dominated by the ³(π → π) state localized on the anthryl moiety, together with a lesser contribution form the ³LLCT state. These changes in the photophys. properties were rationalized by DFT and TDDFT methods.

Category: pyridine-derivatives, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Recommanded Product: Pyridine-3-sulfonyl chloride.

Wang, Fei;Liu, Bo-Xi;Rao, Weidong;Wang, Shun-Yi research published 《 Metal-Free Chemoselective Reaction of Sulfoxonium Ylides and Thiosulfonates: Diverse Synthesis of 1,4-Diketones, Aryl Sulfursulfoxonium Ylides, and β-Keto Thiosulfones Derivatives》, the research content is summarized as follows. A diverse chemoselective insertion reaction of sulfoxonium ylides and thiosulfonates under transition-metal-free conditions is developed, which successfully affords 1,4-diketone compounds, arylthiosulfoxide-ylides, and β-keto thiosulfones, resp. The nucleophilic addition of two mol. sulfoxonium ylides to construct sulfone-substituted 1,4-dione compounds is the highlight of this work.

Recommanded Product: Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Safety of 2-Bromo-6-methylpyridine.

Wagener, Tobias;Lueckemeier, Lukas;Daniliuc, Constantin G.;Glorius, Frank research published 《 Interrupted pyridine hydrogenation: Asymmetric synthesis of δ-lactams》, the research content is summarized as follows. Metal-catalyzed hydrogenation is an effective method to transform readily available arenes into saturated motifs, however, current hydrogenation strategies are limited to the formation of C-H and N-H bonds. The stepwise addition of hydrogen yields reactive unsaturated intermediates that are rapidly reduced. In contrast, the interruption of complete hydrogenation by further functionalization of unsaturated intermediates offers great potential for increasing chem. complexity in a single reaction step. Overcoming the tenet of full reduction in arene hydrogenation has been seldom demonstrated. In this work the authors report the synthesis of sought-after, enantioenriched δ-lactams from oxazolidinone-substituted pyridines and water by an interrupted hydrogenation mechanism.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Safety of 2-Bromo-6-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Category: pyridine-derivatives.

Wade, Nicola;Tehrani, Kamaleddin H. M. E.;Bruechle, Nora C.;van Haren, Matthijs J.;Mashayekhi, Vida;Martin, Nathaniel I. research published 《 Mechanistic Investigations of Metallo-β-lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition**》, the research content is summarized as follows. Metallo-β-lactamases (MBLs) are zinc-dependent bacterial enzymes that inactivate essentially all classes of β-lactam antibiotics including last-resort carbapenems. At present there are no clin. approved MBL inhibitors, and in order to develop such agents it is essential to understand their inhibitory mechanisms. Herein, we describe a comprehensive mechanistic study of a panel of structurally distinct MBL inhibitors reported in both the scientific and patent literature. Specifically, we determined the half-maximal inhibitory concentration (IC₅₀) for each inhibitor against MBLs belonging to the NDM and IMP families. In addition, the binding affinities of the inhibitors for Zn²⁺, Ca²⁺ and Mg²⁺ were assessed by using isothermal titration calorimetry (ITC). We also compared the ability of the different inhibitors to resensitize a highly resistant MBL-expressing Escherichia coli strain to meropenem. These investigations reveal clear differences between the MBL inhibitors studied in terms of their IC₅₀ value, metal binding ability, and capacity to synergize with meropenem. Notably, our studies demonstrate that potent MBL inhibition and synergy with meropenem are not explicitly dependent on the capacity of an inhibitor to strongly chelate zinc.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. Product Details of C6H8N2.

Verevkin, Sergey P.;Zherikova, Kseniya V.;Martynenko, Evgeniya A. research published 《 Molecular versus ionic liquids: Development of a thermodynamic framework for predicting vaporization thermodynamics》, the research content is summarized as follows. Ionic liquids based on the pyridinium and quinolinium cations show good result in desulfurization of fuels. The knowledge of their vaporisation thermodn. is of practical importance. The standard molar enthalpies of vaporization of pyridinium based ionic liquids were derived from the vapor pressure temperature dependences measured by the quartz-crystal microbalance method. We have collected available primary exptl. results on vapor pressures, and enthalpies of phase transitions (solid-solid, crystal-gas, and liquid-gas) of analogus mol. species – substituted pyridines and quinolines. These data were evaluated using the structure-property correlations. The consistent sets of evaluated thermodn. data on the mol. and ionic liquids were used to develop the ′′centerpiece′′ based group-additivity method for predicting enthalpies of vaporization of mol. and ionic compounds The general transferability of the contributions to the enthalpy of vaporization from the mol. liquids to the ionic liquid has been established.

Product Details of C6H8N2, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. COA of Formula: C6H6BrN.

Vanga, Mukundam;Lalancette, Roger A.;Jaekle, Frieder research published 《 Controlling the Optoelectronic Properties of Pyrene by Regioselective Lewis Base-Directed Electrophilic Aromatic Borylation》, the research content is summarized as follows. Pyreno-annelated azaboroles I (5, X = C₁₃H₂₇, R = Ph, Et) and azaborines II (6, Y = C₈H₁₇, R = Ph, Et) were prepared by stepwise borylation-Suzuki coupling of pyrene and examined for their photophys. properties. Given that pyrene represents one of the most versatile chromophores, the development of new selective routes for its functionalization and tuning of its emission properties is highly desirable. Pyrene-based BN Lewis pair (LP)-functionalized polycyclic aromatic hydrocarbons (PAHs) were prepared by regioselective Lewis base-directed electrophilic aromatic substitution. The requisite 1,6-dipyridylpyrene ligands were accessed by Suzuki-Miyaura cross-coupling of 1,6-bis(pinacolatoboryl)pyrenes with 2-bromopyridine derivatives Subsequent electrophilic borylation with BCl₃ in the presence of AlCl₃ and 2,6-di-tert-butylpyridine as a hindered base produced the dichloroborane complexes, which were then in situ reacted with di-Ph or di-Et zinc. The presence or absence of alkyl chains in the 3,8-positions of the pyrene moiety determined the position of the B-C bond formation (2,7 in the non-K region vs. 5,10 in the K region) and thereby also the size of the BN heterocycle (five- vs. six-membered). The impact of the regioisomeric borylation on the electrochem., photophys. and structural properties was investigated and the conclusions supported by theor. calculations The rapid synthesis of derivatives that are borylated in the K region also suggests strong potential for the development of pyrene derivatives that are otherwise difficult to access.

COA of Formula: C6H6BrN, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Synthetic Route of 1603-41-4.

Uysal, Sirin;Soyer, Zeynep;Saylam, Merve;Tarikogullari, Ayse H.;Yilmaz, Sinem;Kirmizibayrak, Petek Ballar research published 《 Design, synthesis and biological evaluation of novel naphthoquinone-4-aminobenzensulfonamide/carboxamide derivatives as proteasome inhibitors》, the research content is summarized as follows. A series of novel 4-aminobenzensulfonamide/carboxamide derivatives I [R = 2-ethylanilino, (2-chloro-3-pyridyl)amino, 1-naphthylamino, etc.] and II [R¹ = anilino, 2-thiazolylamino, 4-nitroanilino, etc.] were designed, sythesized and evaluated for their proteasome inhibitory and antiproliferative activities against human breast cancer cell line (MCF-7). The structures of the synthesized compounds I and II were confirmed by spectral and elemental analyses. The proteasome inhibitory activity studies were carried out using cell-based assay. The antiproteasomal activity results revealed that most of the compounds exhibited inhibitory activity with different percentages against the caspase-like (C-L, β1 subunit), trypsin-like (T-L, β2 subunit) and chymotrypsin-like (ChT-L, β5 subunit) activities of proteasome. Among the tested compounds, compound I [R = (5-chloro-2-pyridyl)amino] was the most active compound in the series and displayed higher inhibition with IC₅₀ values of 9.90 ± 0.61, 44.83 ± 4.23 and 22.27 ± 0.15μM against ChT-L, C-L and T-L activities of proteasome compared to the lead compound PI-083 (IC₅₀ = 12.47 ± 0.21, 53.12 ± 2.56 and 26.37 ± 0.5μM), resp. The antiproliferative activity were also determined by MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) assay in-vitro. According to the antiproliferative activity results, all of the compounds I and _II exhibited cell growth inhibitory activity in a range of IC₅₀ = 1.72 ± 0.14-20.8 ± 0.5μM and compounds I [R = (5-methyl-2-pyridyl)amino] and II [R¹ = (4-methyl-2-pyridyl)amino] were found to be the most active compounds with IC₅₀ values of 1.79 ± 0.21 and 1.72 ± 0.14μM, resp. Furthermore, mol. modeling studies were carried out for the compounds I [R = (5-methyl-2-pyridyl)amino, (5-chloro-2-pyridyl)amino] and II [R¹ = (4-methyl-2-pyridyl)amino] to investigate the ligand-enzyme binding interactions.

Synthetic Route of 1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Formula: C6H4BrNO.

Tsyrenova, Biligma D.;Khrustalev, Victor N.;Nenajdenko, Valentine G. research published 《 Synthesis of blue light emitting heterocycles via cyclization of 2-pyridine derived 4-azido-r1,2,3-triazoles》, the research content is summarized as follows. An efficient synthesis of 2-pyridine derived 4-azido-1,2,3-triazoles I (R = pyridin-2-yl, 6-bromopyridin-2-yl, 8-hydroxyquinolin-2-yl, 1,8-naphthyridin-2-yl, etc.; R¹ = Ph, 4-methylphenyl, 4-fluorophenyl, 3,4-dichlorophenyl, etc.) was elaborated using the corresponding dichlorodiazadienes Cl₂C=C(R)N=NR¹ as precursors. The reaction of the prepared 2-azine substituted diazadienes with sodium azide permits the preparation of target triazoles I isolated in up to 92% yield. Subsequent thermal cyclization was studied. Elimination of mol. nitrogen promoted the cyclization of nitrene at the azine nitrogen. As a result, a family of 2H-[1,2,3]triazolo[4′,5′:3,4]pyrazolo[1,5-a]pyridin-5-ium-4-ides II (R² = H, Me; R³ = H, Me, Br; R²R³ = -CH=CH-CH=CH-, -C(OH)=CH-CH=CH-, -CH=C(CH₃)-CH=CH-, -N=CH-CH=CH-) was prepared The synthesized compounds II are members of a new heterocyclic system. Moreover, these compounds II are new attractive blue light emitting mols.

Formula: C6H4BrNO, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Reference of 5315-25-3.

Tsybizova, Alexandra;Fritsche, Lukas;Gorbachev, Vladimir;Miloglyadova, Larisa;Chen, Peter research published 《 Cryogenic ion vibrational predissociation (CIVP) spectroscopy of a gas-phase molecular torsion balance to probe London dispersion forces in large molecules》, the research content is summarized as follows. We report a gas-phase mol. torsion balance that uses a conformational equilibrium to “weigh” London dispersion against a competing cation-π interaction, for which the readout is the shift in an N-H stretching frequency measured by cryogenic ion vibrational predissociation (CIVP) spectroscopy of electrosprayed pyridinium cations in a Fourier-transform ion cyclotron resonance trap. While frequency calculations with DFT, within the harmonic approximation, assist in the interpretation of the spectra, the observed complex spectrum most likely comes from a Fermi resonance of the N-H stretch with otherwise “dark” overtones of in-plane C-H wagging modes, as argued on the basis of comparison of the spectrum to those for a range of related cations with systematically varied substitution. An equilibrium in favor of the asym. conformer would suggest that the dispersion-corrected DFT calculations tested in this work appear to overestimate significantly the stability of the compact conformations favored by London dispersion in the gas phase, which would then pertain to the use of dispersion energy donors in the design of stereoselective reactions. (c) 2019 American Institute of Physics.

Reference of 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem