Day: November 2, 2022

On June 30, 2008, Qiu, Zhi-Hui; Liang, Fu-Pei; Ruan, Qing-Feng; Zhao, Shan-Rong published an article.Electric Literature of 636-73-7 The title of the article was catena-Poly[[diaquamanganese(II)]-di-μ-pyridine-3-sulfonato-κ2N:O;κ2O:N]. And the article contained the following:

In the title polymeric complex, [Mn(C5H4NO3S)2(H2O)2]n, the Mn atom is located on a center of inversion and is coordinated by two O atoms and two N atoms derived from four different pyridine-3-sulfonate (pySO3) ligands, and two O atoms derived from two H2O mols. in a distorted trans-N2O4 octahedral geometry. The metal atoms are bridged by the pySO3 ligands to form a 1-dimensional chain. The chains are further connected into a three-dimensional architecture via H bonds. Crystallog. data and at. coordinates are given. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Electric Literature of 636-73-7

The Article related to mol structure manganese aqua pyridinesulfonato polymeric complex, crystal structure manganese aqua pyridinesulfonato polymeric complex, hydrogen bond manganese aqua pyridinesulfonato polymeric complex and other aspects.Electric Literature of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ghorai, Debasish; Mueller, Valentin; Keil, Helena; Stalke, Dietmar; Zanoni, Giuseppe; Tkachenko, Boryslav A.; Schreiner, Peter R.; Ackermann, Lutz published an article in 2017, the title of the article was Secondary Phosphine Oxide Preligands for Palladium-Catalyzed C-H (Hetero)Arylations: Efficient Access to Pybox Ligands.Related Products of 109660-12-0 And the article contains the following content:

C-H arylations of oxazolines were accomplished with a well-defined palladium catalyst derived from a secondary bisdiamantyl phosphine oxide. The single-component secondary phosphine oxide (SPO)-palladium complex enabled C-H activations with aryl bromides and challenging aryl chlorides in the absence of directing groups, setting the stage for the step-economical synthesis of pybox ligands under racemization-free reaction conditions. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Related Products of 109660-12-0

The Article related to bisdiamantyl phosphine oxide palladium complex catalyst preparation crystal structure, oxazoline aryl halide phosphine oxide palladium complex catalyst arylation, aryloxazoline regioselective preparation and other aspects.Related Products of 109660-12-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On January 20, 1989, Corey, E. J.; Posner, Gary H.; Atkinson, Richard F.; Wingard, Astrid K.; Halloran, Daniel J.; Radzik, Donna M.; Nash, John J. published an article.Safety of Pyridine-3-sulfonic acid The title of the article was Formation of olefins via pyrolysis of sulfonate esters. And the article contained the following:

Esters, e.g., I and II, of 8-quinolinesulfonic acid and 2-pyridinesulfonic acid were synthesized from alcs. and the acid chlorides. The secondary esters decomposed cleanly at moderate temperatures to give olefins in high yields. Thus, I was heated at 150° to give 92% cyclohexene. Product studies were consistent with carbocation formation and abstraction by a ring nitrogen to give the olefin. The importance of a basic group was confirmed by pyrolysis of a series of para-substituted cyclohexyl benzenesulfonates III (R = NHAc, NHEt, NO2, Br, Me, MeO, Me2N). Thermolysis of III (R = NHEt, NHAc) cleanly gave cyclohexene in good yield; however, thermolysis of III (R = NO2, Br, Me Me) gave cyclohexene in low yield along with considerable amounts of tar. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Safety of Pyridine-3-sulfonic acid

The Article related to olefin preparation sulfonate pyrolysis, pyrolysis sulfonate ester, alkyl quinolinesulfonate preparation thermolysis, pyridinesulfonate preparation thermolysis, thermal elimination alkyl quinolinesulfonate and other aspects.Safety of Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On September 15, 2014, Gouda, Ayman A.; Hashem, Hisham; Jira, Thomas published an article.Recommanded Product: 132-20-7 The title of the article was Development and validation of a rapid stability indicating HPLC-method using monolithic stationary phase and two spectrophotometric methods for determination of antihistaminic acrivastine in capsules. And the article contained the following:

Simple, rapid and accurate high performance liquid chromatog. (HPLC) and spectrophotometric methods are described for determination of antihistaminic acrivastine in capsules. The first method (method A) is based on accurate, sensitive and stability indicating chromatog. separation method. Chromolith Performance RP-18e column, a relatively new packing material consisting of monolithic rods of highly porous silica, was used as stationary phase applying isocratic binary mobile phase of ACN and 25 mM NaH2PO4 pH 4.0 in the ratio of 22.5:77.5 at flow rate of 5.0 mL/min and 40 °C. A diode array detector was used at 254 nm for detection. The elution time of acrivastine was found to be 2.080 ± 0.032. The second and third methods (methods B and C) are based on the oxidation of acrivastine with excess N-bromosuccinimide (NBS) and determination of the unconsumed NBS with, metol-sulfanilic acid (λmax: 520 nm) or amaranth dye (λmax: 530 nm). The reacted oxidant corresponds to the drug content. Beer’s law is obeyed over the concentration range 1.563-50, 2.0-20 and 1.0-10 μg mL-1 for methods A, B and C, resp. The limits of detection and quantitation were 0.40, 0.292 and 0.113 μg mL-1 and 0.782, 0.973 and 0.376 μg mL-1 for methods A, B and C, resp. The HPLC method was validated for system suitability, linearity, precision, limits of detection and quantitation, specificity, stability and robustness. Stability tests were done through exposure of the analyte solution for four different stress conditions and the results indicate no interference of degradants with HPLC-method. The proposed methods was favorably applied for determination of acrivastine in capsules formulation. Statistical comparison of the obtained results from the anal. of the studied drug to those of the reported method using t- and F-tests showed no significant difference between them. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Recommanded Product: 132-20-7

The Article related to chromatog monolithic stationary phase spectrophotometry antihistaminic acrivastine capsule, acrivastine, capsules, monolithic columns, n-bromosuccinimide, spectrophotometry, stability indicating lc-method and other aspects.Recommanded Product: 132-20-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On December 12, 2000, Ankersen, Michael; Stidsen, Carsten Enggaard; Crider, Michael Albert published a patent.Quality Control of N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine The title of the patent was Use of pyridinylaminoalkyl- and imidazolylalkyl-substituted thioureas, isothioureas, and guanidines as somatostatin agonists and antagonists, for treating diseases related to the eye. And the patent contained the following:

The invention relates to the use of somatostatin receptor ligands of nonpeptide origin, e.g., I or II, or a pharmaceutically acceptable salt thereof [wherein: m = 2, 3, 4, 5 or 6; n = 1, 2 or 3; p = 1, 2, 3, 4, 5 or 6; R1, R2 = independently H or C1-6 alkyl optionally substituted with halo, amino, OH, alkoxy, or aryl; X = S, O, NH, NCOPh or N(CN); A = (hetero)aryl optionally substituted with halo, amino, OH, NO2, C1-6 alkyl, C1-6 alkoxy, or aryl, B = (hetero)aryl optionally substituted with halo, amino, OH, C1-6 alkyl, C1-6 alkoxy, or aryl; D = (hetero)aryl or amino, optionally substituted with halo, amino, OH, C1-6 alkyl, C1-6 alkoxy, or aryl]. The compounds have high and/or selective affinity to the somatostatin receptor protein designated SSTR4, and are useful for the preparation of medicaments for treatment of diseases associated with adverse conditions of the retina and/or iris-ciliary body in mammals (no data). Such conditions include high intraocular pressure (IOP) and/or deep ocular infections. The diseases which may be treated are, e.g. glaucoma, stromal keratitis, iritis, retinitis, cataract, and conjunctivitis. Over 40 compounds are claimed for usage, and 27 synthetic examples are given. For instance, propane-1,3-diamine underwent a sequence of: (1) N-arylation with 2-bromopyridine (76%); (2) N-benzylation with NaH and 4-bromobenzyl bromide in DMSO (70%); (3) conversion of the N’-amine to an isothiocyanate using DCC and CS2 (88%); (4) amination of the isothiocyanate with 3-[1-(triphenylmethyl)imidazol-4-yl]propylamine (80%); and (5) deprotection of the trityl group with aqueous HCl in EtOH (99%), to give title compound III.2HCl. The experimental process involved the reaction of N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine(cas: 199522-66-2).Quality Control of N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine

The Article related to thiourea isothiourea guanidine pyridinylaminoalkyl imidazolylalkyl preparation somatostatin agonist antagonist, antiglaucoma somatostatin receptor agonist antagonist thiourea isothiourea guanidine preparation and other aspects.Quality Control of N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On July 30, 1999, Franco, D.; Panyella, D.; Rocamora, M.; Gomez, M.; Clinet, J. C.; Muller, G.; Dunach, E. published an article.Recommanded Product: 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine The title of the article was Electrochemical cleavage of allyl aryl ethers and allylation of carbonyl compounds: umpolung of allyl-palladium species. And the article contained the following:

The electrochem., Pd-catalyzed cleavage of the carbon-oxygen bond of allyl aryl ethers has been examined; the method constitutes a new alternative for allyl ether deprotection. The allyl transfer from the allyl ether to the carbonyl group in 2-allyloxy benzaldehyde is reported and is an example of allyl-Pd reactivity umpolung. Pd(II) complexes, associated to several nitrogen ligands are efficient catalyst precursors for these electrochem. reactions. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Recommanded Product: 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

The Article related to allyl aryl ether electrochem cleavage, electrochem ether cleavage catalyst palladium complex, aryl allyl ether deprotection electrochem cleavage, allylsalicylaldehyde allyl transfer palladium chloride catalyst and other aspects.Recommanded Product: 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 6, 2007, Baysal, Akin; Aydemir, Murat; Durap, Feyyaz; Guemguem, Bahattin; Oezkar, Saim; Yildirim, Leyla Tatar published an article.Formula: C10H10N4 The title of the article was Synthesis and characterizations of 3,3′-bis(diphenylphosphinoamine)-2,2′-bipyridine and 3,3′-bis(diphenylphosphinite)-2,2′-bipyridine and their chalcogenides. And the article contained the following:

New bis(phosphinoamine) and bis(phosphinite) derivatives of 2,2′-bipyridine were prepared through a single step reaction of 3,3′-diamino-2,2′-bipyridine or 3,3′-dihydroxy-2,2′-bipyridine with diphenylchlorophosphine, resp. Their P = E chalcogenide phosphinates (E = O, S, Se) were also prepared All the new compounds were characterized by elemental anal., IR and NMR spectroscopies. The mol. structure of 3,3′-bis(diphenylthiophosphinate)-2,2′-bipyridine was elucidated by single-crystal x-ray crystallog. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Formula: C10H10N4

The Article related to crystal structure bipyridinediyl bisthiophosphinate, mol structure bipyridinediyl bisthiophosphinate, bipyridine phosphinoamino phosphinite preparation oxidation, chalcogenide phosphinate bipyridine preparation and other aspects.Formula: C10H10N4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dang, Qin-Qin; Zhan, Yu-Fen; Duan, Li-Na; Zhang, Xian-Ming published an article in 2015, the title of the article was A pyridyl-decorated MOF-505 analogue exhibiting hierarchical porosity, selective CO2 capture and catalytic capacity.HPLC of Formula: 1431292-15-7 And the article contains the following content:

An expanded pyridyl-decorated MOF-505 analog [Cu2(L)(H2O)2]·Gx (H4L = 5,5′-(pyridine-2,5-diyl)diisophthalic acid, G = solvent mol.) was solvothermally synthesized and reported. It exhibited rare hierarchical meso- and microporosity. With exposed unsaturated CuII sites and Lewis basic pyridyl sites, the material shows both large CO2-uptake capacity (123.4 cm3 g-1 at 273 K, 1 bar) and high selectivity for CO2 over N2 (55.7) at 273 K. Also, for the first time the compound was exploited for its heterogeneous catalytic performance toward the cyanosilylation reaction under solvent-free conditions. The compound can be recycled up to five times with only a minor loss of activity. The experimental process involved the reaction of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid(cas: 1431292-15-7).HPLC of Formula: 1431292-15-7

The Article related to copper pyridinediyldiisophthalate mof solvothermal preparation crystal structure, gas adsorption copper pyridinediyldiisophthalate mof, aryl aldehyde cyanosilylation catalyst copper pyridinediyldiisophthalate mof and other aspects.HPLC of Formula: 1431292-15-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yang, Bing; Jiang, Xin; Guo, Qing; Lei, Tao; Zhang, Li-Ping; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu published an article in 2016, the title of the article was Self-Assembled Amphiphilic Water Oxidation Catalysts: Control of O-O Bond Formation Pathways by Different Aggregation Patterns.Formula: C5H5NO3S And the article contains the following content:

The oxidation of water to mol. oxygen is the key step to realize water splitting from both biol. and chem. perspective. In an effort to understand how water oxidation occurs on a mol. level, a large number of mol. catalysts have been synthesized to find an easy access to higher oxidation states as well as their capacity to make O-O bond. However, most of them function in a mixture of organic solvent and water and the O-O bond formation pathway is still a subject of intense debate. Herein, we design the first amphiphilic Ru-bda (H2bda=2,2′-bipyridine-6,6′-dicarboxylic acid) water oxidation catalysts (WOCs) of formula [RuII(bda)(4-OTEG-pyridine)2] (1, OTEG=OCH2CH2OCH2CH2OCH3) and [RuII(bda)(PySO3Na)2] (2, PySO3-=pyridine-3-sulfonate), which possess good solubility in water. Dynamic light scattering (DLS), scanning electron microscope (SEM), critical aggregation concentration (CAC) experiments and product anal. demonstrate that they enable to self-assemble in water and form the O-O bond through different routes even though they have the same bda2- backbone. This work illustrates for the first time that the O-O bond formation pathway can be regulated by the interaction of ancillary ligands at supramol. level. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Formula: C5H5NO3S

The Article related to self assembled amphiphilic water oxidation catalyst, control oxygen oxygen bond formation pathway different aggregation pattern, amphiphilic complexes, catalysis, ruthenium complex, self-assembly, water oxidation and other aspects.Formula: C5H5NO3S

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On November 9, 2000, Dow, Robert Lee; Liu, Kevin Kun-Chin; Morgan, Bradley Paul; Swick, Andrew Gordon published a patent.Reference of 4-(Chloromethyl)-2-methoxy-6-methylpyridine The title of the patent was Preparation of nonracemic octahydrophenanthrene and other tricyclic derivatives as selective modulators of glucocorticoid receptors. And the patent contained the following:

Title compounds [e.g., I; D = CR7, CR7R16, N, NR7, O’ E = C, CR6, N; F = CR4, CR4R5, O; R = XR1; R1 = H, alkyl, acylalkyl, arylalkyl, etc.; R2 = H, halo, alkyl, alkoxy, etc.; R3 = H, alkyl, arylalkyl, etc.; 1 of R2,R3 = null when adjacent dashed line = bond; R4,R5 = H, cyano, alkyl, alkoxy, etc.; R4R5 = O; R6 = H, cyano, alkyl, alkoxy, OH, etc.; R7,R16 = H, halo, cyano, alkyl, etc.; R7R16 = O; R8R9 = atoms to complete a substituted heteroaromatic ring; R14,R15 = H, halo, alkyl, alkoxy, etc.; R14R15 = O when adjacent dashed lines = null; X = bond, CH2, CH(OH), CO; Z = (un)substituted CH2, -CH2CH2, -CH2CO, CO, etc.; dashed lines = optional bonds] were prepared as glucocorticoid receptor modulators (no data). E.g., 6-methoxy-2-tetralone was alkylated by formation of the pyrrolidine enamine and alkylation with benzyl bromide; the benzylated ketone then undergoes asym. Michael addition with Me vinyl ketone in the presence of (S)-(-)-α-methylbenzylamine followed by cyclocondensation with sodium methoxide to give a nonracemic methoxytetrahydrophenanthrenone derivative E.g., demethylation of the methoxytetrahydrophenanthrenone with boron trichloride, reduction of the enone with lithium and ammonia, addition of 1-lithiopropyne to the ketone, formation of the aryl triflate with triflic anhydride and carbonylation with carbon monoxide in the presence in the presence of palladium acetate and bis(diphenylphosphino)propanol gives an hydroxyoctahydrophenanthrenecarboxylic acid derivative which is coupled with 4-(aminomethyl)pyridine in the presence of trimethylaluminum to give the octahydrophenanthrenecarboxamide II as one of the title compounds The experimental process involved the reaction of 4-(Chloromethyl)-2-methoxy-6-methylpyridine(cas: 1227595-34-7).Reference of 4-(Chloromethyl)-2-methoxy-6-methylpyridine

The Article related to nonsteroidal glucocorticoid receptor selective agonist antagonist preparation, treatment obesity diabetes inflammation nonsteroidal glucocorticoid receptor modulator, glucocorticoid receptor modulator preparation and other aspects.Reference of 4-(Chloromethyl)-2-methoxy-6-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem