Day: November 4, 2022

On January 3, 2021, Zhang, Huimiao; Toy, Patrick H. published an article.Quality Control of [2,2′-Bipyridine]-3,3′-diamine The title of the article was Halogen Bond-Catalyzed Friedel-Crafts Reactions of Furans Using a 2,2′-Bipyridine-Based Catalyst. And the article contained the following:

A halogen bond donor based on a 2,2′-bipyridine framework I has been synthesized, and used to catalyze Friedel Crafts reactions of furans II (R = H, Me, t-Bu). Electrophiles used successfully in these reactions included various enones such as 3-buten-2-one, crotonophenone, cyclohexenone, etc.; benzaldehyde, and acetic anhydride. The yields of the reactions were generally good using a moderate catalyst loading (0.025 or 0.1 equivalent) at a relatively low temperature (room temperature or 50°C) in acetonitrile. The catalyst was designed with a biaryl scaffold so that if it indeed proved to be an efficient halogen bond donor organocatalyst, an enantioenriched version of it could potentially serve as a stereoselective catalyst. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Quality Control of [2,2′-Bipyridine]-3,3′-diamine

The Article related to furan electrophile friedel craft reaction halogen bond bipyridine catalyst, Heterocyclic Compounds (One Hetero Atom): Furans and other aspects.Quality Control of [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On April 30, 2000, Hoffmann, Reinhard W.; Caturla, Francisco; Lazaro, Miguel A.; Framery, Eric; Carmen Bernabeu, M.; Valancogne, Ingrid; Montalbetti, Christian A. G. N. published an article.Formula: C23H19BrN2O4 The title of the article was Conformational analysis of 4-amido-2,4-dimethylbutyric acid derivatives. And the article contained the following:

Several protected 4-amido-2,4-dimethylbutyrates were prepared Both, syn- and anti-4-amido-2,4-dimethylbutyric acid derivatives were found to populate a conformation in which the amido group is gauche to the main chain of the mol. In the anti series, a single conformation predominates, in which the acid carbonyl group is also gauche to the main chain. In the syn series, two local conformers prevail about the C(2)-C(3) bond. The experimental process involved the reaction of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid(cas: 282734-37-6).Formula: C23H19BrN2O4

The Article related to amidomethylbutyrate preparation conformation, butyrate amido methyl preparation conformation, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Formula: C23H19BrN2O4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On December 7, 2003, Tabanella, Stefania; Valancogne, Ingrid; Jackson, Richard F. W. published an article.Application In Synthesis of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid The title of the article was Preparation of enantiomerically pure pyridyl amino acids from serine. And the article contained the following:

A range of substituted pyridyl amino acids have been prepared by palladium catalyzed cross-coupling of serine-derived organozinc reagents with differently substituted halopyridines. Following this procedure a DMAP analog has been synthesized and used as a building block in the preparation of two related tripeptides, which have been tested as catalysts in the kinetic resolution of trans-2-(N-acetylamino)cyclohexan-1-ol, resulting in modest enantioselectivity. The experimental process involved the reaction of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid(cas: 282734-37-6).Application In Synthesis of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid

The Article related to pyridyl amino acid preparation cross coupling organozinc serine, kinetic resolution catalyst pyridyl amino acid, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Application In Synthesis of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kaczmarek, T. D.; Phillips, D. C.; Smith, J. D. B. published an article in 1977, the title of the article was Organoparticulate analysis of amine arenesulfonates.Formula: C5H5NO3S And the article contains the following content:

Thermal decompn of PhSO3H, p-MeC2H4SO3H, 3-pyridinesulfonic acid, and 1-naphthalenesulfonic acid and of 17 amine salt derivatives were studied by the title method. Vapor phase association of the end product was observed The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Formula: C5H5NO3S

The Article related to organoparticulate analysis decomposition arenesulfonate, sulfonate amine decomposition, Physical Organic Chemistry: Degradation Reactions and other aspects.Formula: C5H5NO3S

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bhagat, Rakshanda; Sheikh, Amir Amin; Dar, Rouf Rashid; Dogra, Pooja; Islam, Sheikh Tajamul published an article in 2017, the title of the article was A clinical case of ear canker and alopecia in a rabbit.Safety of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate And the article contains the following content:

A two year old male rabbit was presented with history of itching; rough hair coat and hair fall from last 15 days with reddish brown crust formation on ears, paws and around eyes. Skin scraping revealed the presence of Psoroptes cuniculi (ear mite) thus diagnosing the case of ear canker. Treatment with Ivermectin (Ivomec) @ 0.02mg/kg S.c. weekly for 4 wk, Pheniramine maleate (Avil) @ 0.5 mg/kg I.m. and topical application of honey and turmeric mix daily for 1 wk was accomplished which resulted in substantial clin. improvement recorded in terms of decreased frequency of itching, regained smooth hair coat and lusture of hair and skin. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Safety of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate

The Article related to ear canker alopecia rabbit, Mammalian Pathological Biochemistry: Skin Diseases and other aspects.Safety of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kaji, Ayumi; Hashimoto, Yoshitaka; Sakai, Ryosuke; Okada, Hiroshi; Hamaguchi, Masahide; Ushigome, Emi; Majima, Saori; Yamazaki, Masahiro; Fukui, Michiaki published an article in 2019, the title of the article was Frequent usage of convenience stores is associated with low diet quality.Application In Synthesis of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate And the article contains the following content:

In Japan, convenience stores are more common, and it is thus more important to assess whether people use convenience stores than the d. or availability of the convenience stores. In this cross-sectional study of patients with type 2 diabetes, the association between the usage of the convenience stores and dietary habits or the prevalence of hypertension was evaluated. Among the 206 men and 161 women in the study, 24 men and 9 women used convenience stores three or more times per wk. Fruit and vegetable intake (men, 132 (102-191) vs. 192 (128-267) g/1000 kcal, p = 0.019; and women, 178 (132-207) vs. 239 (172-313) g/1000 kcal, p = 0.063) of patients who frequently use convenience stores was lower compared to those who did not. Net endogenous acid production score (men, 55.2 (45.4-65.2) vs. 48.9 (42.3-56.8) mEq/day, p = 0.013; and women, 56.9 (52.6-59.8) vs. 46.3 (40.9-54.0) mEq/day, p = 0.050) and intake of carbohydrate to fiber ratio (men, 21.5 (20.0-29.3) vs. 19.9 (15.7-25.0), p = 0.052; and women, 21.0 (18.9-23.9) vs. 16.2 (13.8-20.3), p = 0.017) of patients who frequently use convenience stores were higher compared to those who did not. Addnl., frequent usage of convenience stores was associated with the prevalence of hypertension after adjusting for covariates (5.01; 95% confidence interval, 1.12-22.50; p = 0.035). In conclusion, frequent usage of convenience stores is associated with low diet quality and the prevalence of hypertension. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Application In Synthesis of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate

The Article related to diabetes convenience store low diet quality, convenience store, diet quality, food environment, habitual diet intake, lifestyle, type 2 diabetes, Animal Nutrition: Carbohydrates, Fiber, and Energy and other aspects.Application In Synthesis of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 6, 1996, Suzuki, Masashi published a patent.Formula: C7H10N2 The title of the patent was Preparation of methylaminopyridine derivatives in high-yield. And the patent contained the following:

The title compounds (I; R = C1-4 alkyl, n = 1-2, X = NHMe) can be efficiently and economically produced by reaction of I (X = NH2, R, n = same as above) with a mixture of (HCO)2O and (AcO)2O or with HCO2H in the presence of (AcO)2O, followed by reduction of formyl group. I are useful intermediates in the production of drugs and pesticides. Thus, I (Rn = 4-Me and 6-Me, X = NH2) was reacted with HCO2H in the presence of (AcO)2O to give 85% I (Rn = 4-Me and 6-Me, X = NHCHO), which was reduced by LiAlH4 to give 97% I (Rn = 4-Me and 6-Me, X = NHMe). The experimental process involved the reaction of N,3-Dimethylpyridin-2-amine(cas: 156267-13-9).Formula: C7H10N2

The Article related to methylaminopyridine preparation, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Formula: C7H10N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 31, 1985, Tsiropoulos, G. J. published an article.Computed Properties of 636-73-7 The title of the article was Dietary administration of antivitamins affected the survival and reproduction of Dacus oleae. And the article contained the following:

Fifteen antivitamins were tested, at various concentrations, on the adult olive fruit fly, D. oleae. Fly survival was affected by the following antivitamins, indicating in parenthesis the antagonized vitamin: benzimidazole  [51-17-2] (B-12), α-picolinic acid  [98-98-6] (nicotinic acid), deoxypyridoxine  [61-67-6] (pyridoxine), neopyrithiamine  [534-64-5] (thiamin), and α-tocopherol quinone  [7559-04-8] (vitamin E). Egg production was significantly reduced by the same antivitamins, plus, dl-desthiobiotin  [636-20-4] (biotin), aminopterin  [54-62-6] (folic acid), isonicotinic acid  [55-22-1], nicotinic acid diethylamide  [59-26-7] (nicotinic acid), and dehydroascorbic acid  [490-83-5] (vitamin C). Fertility was significantly affected by: benzimidazole (B-12), dl-desthiobiotin (biotin), aminopterin (folic acid), isonicotinic acid (nicotinic acid), deoxypyridoxine (pyridoxine), neopyrithiamine (thiamin), tocopherol quinone (vitamin E), and dehydroascorbic acid (vitamin C). The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Computed Properties of 636-73-7

The Article related to dacus feed antivitamin reproduction, Food and Feed Chemistry: Contaminants and Toxicants and other aspects.Computed Properties of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On June 30, 2007, Rao, Chepuri R. K.; Trivedi, D. C. published an article.Synthetic Route of 636-73-7 The title of the article was Tailoring the gold-polypyrrole nanostructures at water-toluene interphase. And the article contained the following:

A method is described to obtain gold-polypyrrole nanostructures by reacting gold chloride with pyrrole at toluene-water interphase. By adjusting the concentration of the stabilizer, namely, pyridine-3-sulfonate, the shape of the nanostructures formed at the interphase can be tailored. This novel method facilitates the fabrication of Au-Ppy composite material that gives wider scope for biosensing applications. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Synthetic Route of 636-73-7

The Article related to gold polypyrrole nanocomposite biosensor, Plastics Fabrication and Uses: Plastic Product Uses and other aspects.Synthetic Route of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 20, 2010, Lamberto, Massimiliano; Rastede, Elizabeth E.; Decker, Justyne; Raymo, Francisco M. published an article.Computed Properties of 52243-87-5 The title of the article was Microwave-assisted synthesis of symmetric and asymmetric viologens. And the article contained the following:

Viologens are generally synthesized by N-alkylating 4,4′-bipyridine with alkyl halides. Under conventional heating conditions, however, their synthesis suffers from long reaction times and, often, low yields. In this work, sym. and asym. viologens were synthesized under the assistance of microwave irradiation in good to excellent yields and in short reaction times. The experimental process involved the reaction of 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide(cas: 52243-87-5).Computed Properties of 52243-87-5

The Article related to sym asym viologen microwave assisted synthesis, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Computed Properties of 52243-87-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem