Day: November 10, 2022

Li, Zhuang; Cheng, Xian-Yan; Yang, Ning-Yuan; Chen, Ji-Jun; Tang, Wen-Yue; Bian, Jun-Qian; Cheng, Yong-Feng; Li, Zhong-Liang; Gu, Qiang-Shuai; Liu, Xin-Yuan published their research in Organometallics in 2021. The article was titled 《A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)-C(sp2) Cross-Coupling with Chiral Multidentate N,N,P-Ligand》.Quality Control of 4-Acetylpyridine The article contains the following contents:

A cobalt-catalyzed enantioconvergent radical Negishi C(sp3)-C(sp2) cross-coupling of racemic benzyl chlorides with arylzinc reagents has been developed in good yield with moderate enantioselectivities. This strategy provides an expedient access toward a range of enantioenriched 1,1-diarylmethanes. Key to this discovery is the utilization of a chiral multidentate anionic N,N,P-ligand to strongly coordinate with the cobalt catalyst and tune its chiral environment, thus achieving the enantiocontrol over the highly reactive prochiral alkyl radical species. In the part of experimental materials, we found many familiar compounds, such as 4-Acetylpyridine(cas: 1122-54-9Quality Control of 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Quality Control of 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Campos, Joana F.; Cailler, Manon; Claudel, Remi; Prot, Benjamin; Besson, Thierry; Berteina-Raboin, Sabine published an article in 2021. The article was titled 《Demonstration of green solvent performance on O,S,N-heterocycles synthesis: metal-free click chemistry and Buchwald-Hartwig coupling》, and you may find the article in Molecules.Application In Synthesis of 2-Bromo-5-methylpyridine The information in the text is summarized as follows:

In this work, the efficiency of three solvents: eucalyptol (1,8-cineole), cyclopentyl Me ether (CPME), and 2-methyltetrahydrofuran (2-MeTHF) for the synthesis of O,S,N-heterocyclic compounds e.g., I was demonstrated. In the experimental materials used by the author, we found 2-Bromo-5-methylpyridine(cas: 3510-66-5Application In Synthesis of 2-Bromo-5-methylpyridine)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Application In Synthesis of 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Punia, Monika; Khatkar, Satyender Pal; Taxak, Vinod Bala; Dhankhar, Priyanka; Boora Doon, Priti published an article in 2021. The article was titled 《Synthesis of cool white light emitting novel dysprosium (Dy3+) complexes with tetradentate β-ketoamide and heterocyclic auxiliary ligands》, and you may find the article in Luminescence.Computed Properties of C12H12N2 The information in the text is summarized as follows:

To improve current multiphase white light emitting diodes (WLEDs), a novel series of five complexes consisting of one binary and four ternary complexes that emitted cool white light was successfully synthesized using a chelating tetradentate ligand and auxiliary ligands, i.e. 5,6-dimethyl-1,10-phenanthroline, 1,10-phenanthroline, 4,4′-dimethyl-2,2′-bipyridyl, and 2,2′-bipyridyl. The series was examined structurally using elemental anal., Fourier transform IR spectroscopy, energy dispersive X-ray anal., UV-visible spectroscopy, and proton NMR spectroscopy. These complexes had the appropriate thermal stability required for the generation of white organic LEDs (WOLEDs). Dysprosium (III) (Dy3+) ion complexes demonstrated the characteristic emission peaks of blue color at 482 nm and yellow color at 572 nm, resp., when excited using near UV light. Band gap, refractive index, and decay lifetime of the optimized samples were recorded as 2.68 eV, 2.12, and 1.601 ms, resp. Correlated color temperature value (7875 K), Commission International de l′Eclairage coordinates (0.300, 0.294), and color purity (21.04 x 10-2) of the optimized complex were near to those of white illuminants as defined by the National Television System Committee. These complexes had promise as com. LEDs for the advanced optoelectronics devices, especially as WOLEDs for illumination applications. In the experiment, the researchers used many compounds, for example, 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Computed Properties of C12H12N2)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.Computed Properties of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Deeba, Rana; Chardon-Noblat, Sylvie; Costentin, Cyrille published an article in 2021. The article was titled 《Molecular Catalysis of Electrochemical Reactions: Competition between Reduction of the Substrate and Deactivation of the Catalyst by a Cosubstrate Application to N2O Reduction》, and you may find the article in ChemElectroChem.Computed Properties of C6H4N2 The information in the text is summarized as follows:

In the context of mol. catalysis of electrochem. reactions, the competition between reduction of the substrate and deactivation of the catalyst by a cosubstrate is investigated. It is a frequent situation because proton donors are ubiquitous cosubstrates in reductive electrochem. reactions and mol. catalysts, either transition metal complexes or organic aromatic mols., and are often prone to electrohydrogenation. We provide a formal kinetic anal. in the framework of cyclic voltammetry, and we show that the response is governed by two parameters and that the competition does not depend on the scan rate. From this anal. a methodol. is proposed to analyze such systems and then illustrated via the study of N2O to N2 electroreduction catalyzed by 4-cyanopyridine in acetonitrile electrolyte with water as proton donor. Incidentally, new insights into the mechanism of 4-cyanopyridine radical anion protonation are revealed. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanopyridine(cas: 100-48-1Computed Properties of C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Computed Properties of C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Zhang, Lin; Zhang, Ling; Chen, Qian; Li, Linlin; Jiang, Jian; Sun, Hao; Zhao, Chong; Yang, Yuanyong; Li, Chun published an article in Organic Letters. The title of the article was 《Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones》.HPLC of Formula: 1122-54-9 The author mentioned the following in the article:

Herein, a series of novel and easily accessed cinchona-alkaloid-based NNP ligands I [R = cyclohexyl, Ph, 2-MeOC6H4, etc.; R1 = H, MeO] was developed in two steps. By combining [Ir(COD)Cl]2, 39 ketones including aromatic, heteroaryl, and alkyl ketones were hydrogenated, all affording valuable chiral secondary alcs. with 96.0-99.9% ee. A plausible reaction mechanism was discussed by NMR, HRMS, DFT and an activating model involving trihydride was verified. In the experimental materials used by the author, we found 4-Acetylpyridine(cas: 1122-54-9HPLC of Formula: 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. HPLC of Formula: 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Fischer, Christian; Veprek, Nynke A.; Peitsinis, Zisis; Ruhmann, Klaus-Peter; Yang, Chao; Spradlin, Jessica N.; Dovala, Dustin; Nomura, Daniel K.; Zhang, Yingkai; Trauner, Dirk published an article in Synlett. The title of the article was 《De novo Design of SARS-CoV-2 Main Protease Inhibitors》.Related Products of 2510-22-7 The author mentioned the following in the article:

The COVID-19 pandemic prompted many scientists to investigate remedies against SARS-CoV-2 and related viruses that are likely to appear in the future. As the main protease of the virus, M Pro, is highly conserved among coronaviruses, it has emerged as a prime target for developing inhibitors. Using a combination of virtual screening and mol. modeling, we identified small mols. that were easily accessible and could be quickly diversified. Biochem. assays confirmed a class of pyridones as low micromolar noncovalent inhibitors of the viral main protease. In the experiment, the researchers used many compounds, for example, 4-Ethynylpyridine(cas: 2510-22-7Related Products of 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Related Products of 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Su, Fangyao; Zhao, Qianrui; Wang, Mengzhuo; Zhao, Mingzhang; Ren, Yihe; Zhu, Binghan; Chen, Haoran; Lai, Miao; Zhao, Mingqin published an article in ChemistrySelect. The title of the article was 《A Convenient Esterification of N-Heteroarene Methanols via C-CN Bond Cleavage of Benzoyl Cyanides as Acylating Sources》.Formula: C7H9NO The author mentioned the following in the article:

An efficient and straightforward methodol. for the esterification of various N-heteroarene methanols using benzoyl cyanides as acylating sources through a simply mixing conditions has been reported. The acyl groups were in-situ generated via chemoselective C-CN bond cleavage to give the N-heteroarenemethyl esters. This process features in readily accessible starting materials and offers an easy operational procedure, and broad substrate scope with excellent selectivity. In the experiment, the researchers used many compounds, for example, 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Formula: C7H9NO)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Formula: C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Yang, Mingxue; Zhao, Tian-Xiang; Ji, Si-Chao; Tao, Xiao-Dong; Chen, Xu-Lin; Meng, Lingyi; Liang, Dong; Lu, Can-Zhong published an article in Nanomaterials. The title of the article was 《Voltage-Dependent Emission Varying from Blue to Orange-Red from a Nondoped Organic Light-Emitting Diode with a Single Emitter》.Reference of 2,5-Dibromopyridine The author mentioned the following in the article:

Organic light-emitting diodes (OLEDs) with tunable emission colors, especially white OLEDs, have rarely been observed with a single emitter in a single emissive layer. In this paper, we report a new compound featuring a D-A-D structure, 9,9′-(pyrimidine-2,5-diylbis(2,1-phenylene))bis(3,6-di-tert-butyl-9H-carbazole) (PDPC). A nondoped OLED using this compound as a single emitter exhibits unique voltage-dependent dual emission. The emission colors range from blue to orange-red with an increase in voltage, during which white electroluminescence with a Commission Internationale De L′Eclairage (CIE) coordinate of (0.35, 0.29) and a color render index (CRI) value of 93 was observed A comparative study revealed that the dual emission simultaneously originates from the monomers and excimers of the emitter. This study provides insight into understanding the multimer-excited mechanism and developing novel color-tunable OLEDs. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dibromopyridine(cas: 624-28-2Reference of 2,5-Dibromopyridine)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Reference of 2,5-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Wu, Yimei; Simpson, M. Cather; Jin, Jianyong published an article in ChemistrySelect. The title of the article was 《A 3D Printing of Thiol-Yne Photoresins through Visible Light Photoredox Catalysis》.Related Products of 94928-86-6 The author mentioned the following in the article:

In this work, we report a visible light active thiol-yne photoresin formulation that is printable with digital light processing (DLP) 3D printer under irradiation of blue-light (λmax=470 nm). The resulting objects have the Z axis resolution of 250μm (layer thickness) and building speed of (5 mm/h). Uniquely, our thiol-yne photoresin contains photoredox catalysts Eosin Y and fac-Ir(ppy)3, which initiate the photopolymerization through a photoredox mechanism. The optimized dual catalysts EY/fac-Ir(ppy)3 system not only facilitate the faster thiol-yne reaction but also potentially enables wider visible light wavelength coverage for 3D printing process. This work illustrates the possibility of replacing traditional photoinitiator with photoredox catalysts in the visible light range, thus, enriching the photoresin formulations for polymer-based 3D printing industry. The experimental part of the paper was very detailed, including the reaction process of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Related Products of 94928-86-6)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Related Products of 94928-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Recommanded Product: 3510-66-5In 2020 ,《Synthesis of Benzo-Fused 11H-Pyrido[2,1-b]quinazolin-11-ones by a Buchwald-Hartwig Coupling/Pyridine Dearomatization Sequence in Eucalyptol》 appeared in Synthesis. The author of the article were Campos, Joana F.; Pacheco-Benichou, Alexandra; Fruit, Corinne; Besson, Thierry; Berteina-Raboin, Sabine. The article conveys some information:

The synthesis of a new library of polyheterocyclic 11H-pyrido[2,1-b]quinazolin-11-one derivatives was investigated. Satisfactory conditions were obtained via sequential C-N Buchwald-Hartwig coupling and pyridine dearomatization. In this work, traditional solvents were replaced by the bio-sourced eucalyptol, confirming the interest in it as a green solvent in chem. The experimental part of the paper was very detailed, including the reaction process of 2-Bromo-5-methylpyridine(cas: 3510-66-5Recommanded Product: 3510-66-5)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Recommanded Product: 3510-66-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem