Day: November 22, 2022

Real-time observation of multi-mode vibronic coherence in pentafluoropyridine was written by Kus, J. A.;Hueter, O.;Temps, F.. And the article was included in Journal of Chemical Physics in 2017.Reference of 700-16-3 The following contents are mentioned in the article:

The ultrafast dynamics of pentafluoropyridine in the 1 ¹B₂ (ππ*) electronic state excited at λ_pump = 255 nm was studied by femtosecond time-resolved time-of-flight mass spectrometry and photoelectron imaging spectroscopy. A pronounced, long-lived, and complex periodic modulation of the transient ion yield signal with contributions by four distinct frequency components, 72 cm^-1, 144 cm^-1, 251 cm^-1, and 281 cm^-1, is observed for up to 9 ps. The recorded photoelectron images display a spectral band from the excited 1 ¹B₂ (ππ*) state only in the oscillation maxima; the signal is strongly reduced in the oscillation min. Supported by electronic structure calculations at the RI-SCS-CC2 and XMCQDPT2 levels of theory, the oscillating components of the signal are identified as frequencies of b₁ symmetry coupling modes in a vibronic coherence of the 1 ¹B₂ (ππ*) and 1 ¹A₂ (πσ*) electronic states. The optical excitation initiates regular and periodic wavepacket motion along those out-of-plane modes. In the distorted mol. structure, the initially excited state acquires substantial πσ* character that modulates the transition dipole moment for ionization and results in the observed oscillations. (c) 2017 American Institute of Physics. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Reference of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Reference of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adsorption characteristics of aromatic pollutants and their halogenated derivatives on bio-based poly (ether-pyridine)s was written by Gomri, Marwen;Abderrazak, Houyem;Chabbah, Taha;Souissi, Radhia;Saint-Martin, Patrice;Casabianca, Herve;Chatti, Saber;Mercier, Regis;Errachid, Abdelhamid;Hammami, Mohamed;Jaffrezic-Renault, Nicole. And the article was included in Journal of Environmental Chemical Engineering in 2020.Reference of 700-16-3 The following contents are mentioned in the article:

In this work, innovative poly(ether pyridine) polymers obtained from bio-based monomers and pentafluoropyridine derivatives were elaborated in order to adsorb aromatic pollutants and their halogenated derivatives These polymers were obtained with satisfactory yields by polycondensation of four pyridinium monomers (resp. based on morpholine, piperazine, dimethylamine and phenol) with isosorbide or bisphenol A. The adsorption efficiency data demonstrate that the poly(ether pyridine) based on isosorbide and morpholine-based monomer (P2) is the more efficient sorbent toward aromatic pollutants and their derivatives Four aromatic pollutants, p-hydroxybenzoic acid, toluic acid, deisopropylatrazine, and 2,4,6-trichlorophenol, were chosen as the adsorbate to investigate the adsorption efficiency, kinetics and isotherms of the poly(ether pyridine) P2. The results demonstrate that the pseudo-second order was the best to describe the adsorption of the four target pollutants by the efficient sorbent P2 with good correlation. The exptl. data of the four target pollutants adsorption were analyzed by Langmuir and Freundlich isotherms. Polymer P2 shows very high affinity (low 1/n value) for p-hydroxybenzoic acid and for 2,4,6-trichlorophenol, compared to other adsorbents. Three consecutive adsorption/desorption cycles toward eight aromatic pollutants were obtained for the efficient sorbent P2. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Reference of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Reference of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from Fusobacterium nucleatum. was written by He, Shanru;Chen, Yuanyuan;Wang, Lulu;Bai, Xue;Bu, Tingting;Zhang, Jie;Lu, Ming;Ha, Nam-Chul;Quan, Chunshan;Nam, Ki Hyun;Xu, Yongbin. And the article was included in Molecules (Basel, Switzerland) in 2022.Formula: C8H10NO6P The following contents are mentioned in the article:

Pyridoxal 5′-phosphate (PLP) is the active form of vitamin B6, but it is highly reactive and poisonous in its free form. YggS is a PLP-binding protein found in bacteria and humans that mediates PLP homeostasis by delivering PLP to target enzymes or by performing a protective function. Several biochemical and structural studies of YggS have been reported, but the mechanism by which YggS recognizes PLP has not been fully elucidated. Here, we report a functional and structural analysis of YggS from Fusobacterium nucleatum (FnYggS). The PLP molecule could bind to native FnYggS, but no PLP binding was observed for selenomethionine (SeMet)-derivatized FnYggS. The crystal structure of FnYggS showed a type III TIM barrel fold, exhibiting structural homology with several other PLP-dependent enzymes. Although FnYggS exhibited low (<35%) amino acid sequence similarity with previously studied YggS proteins, its overall structure and PLP-binding site were highly conserved. In the PLP-binding site of FnYggS, the sulfate ion was coordinated by the conserved residues Ser201, Gly218, and Thr219, which were positioned to provide the binding moiety for the phosphate group of PLP. The mutagenesis study showed that the conserved Ser201 residue in FnYggS was the key residue for PLP binding. These results will expand the knowledge of the molecular properties and function of the YggS family. This study involved multiple reactions and reactants, such as (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7Formula: C8H10NO6P).

(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Formula: C8H10NO6P

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A Study of the Reichardt E^NT(30) Parameter using Solvent Molecular Properties Derived from Computation Chemistry and Consideration of the Kamlet and Taft α Scale of Solvent Hydrogen Bond Donor Acidities was written by Waghorne, W. Earle. And the article was included in Journal of Solution Chemistry.Recommanded Product: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

Reichardt′s normalized E^NT(30) parameter for solvent polarity has been analyzed in terms of properties of solvent mols. estimated from quantum-mech. calculations of isolated solvent mols. The analyses show that E^NT(30) has a strong dependence on the partial charge on the most pos. hydrogen atom in the solvent mol., reflecting hydrogen bonding at the pendant oxygen atom of the betaine dye used to define the ET(30) scale. There are smaller, and roughly equal, dependences on the dipole moments and quadrupolar amplitudes of the solvent mols. and an inverse dependence on the solvent polarizability. These three dependences reflect the solvent polarity, i.e., the ability to stabilize charge through longer-range interactions. The reason for the inverse dependence on the solvent polarizability is unclear, but a similar dependence was found previously in the anal. of the Kamlet, Abboud and Taft π* scale. The resulting equation for E^NT(30) reproduces the exptl. values for around 160 solvents, representing most classes of organic solvents, with a standard deviation of around 0.07 {E^NT(30) values range from 0 to 1}. The results of the present analyses of E^NT(30) and earlier analyses of π* indicate that, while the α values capture the effect of solvent hydrogen bond donor acidity, it also contains residual dependences on other mol. properties. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A novel panel of yeast assays for the assessment of thiamin and its biosynthetic intermediates in plant tissues was written by Strobbe, Simon;Verstraete, Jana;Fitzpatrick, Teresa B.;Faustino, Maria;Lourenco, Tiago F.;Oliveira, M. Margarida;Stove, Christophe;Van Der Straeten, Dominique. And the article was included in New Phytologist in 2022.SDS of cas: 54-47-7 The following contents are mentioned in the article:

Thiamin (or thiamine), known as vitamin B1, represents an indispensable component of human diets, being pivotal in energy metabolism Thiamin research depends on adequate vitamin quantification in plant tissues. A recently developed quant. liquid chromatog.-tandem mass spectrometry (LC-MS/MS) method is able to assess the level of thiamin, its phosphorylated entities and its biosynthetic intermediates in the model plant Arabidopsis thaliana, as well as in rice. However, their implementation requires expensive equipment and substantial tech. expertise. Microbiol. assays can be useful in deter-mining metabolite levels in plant material and provide an affordable alternative to MS-based anal. Here, we evaluate, by comparison to the LC-MS/MS reference method, the potential of a carefully chosen panel of yeast assays to estimate levels of total vitamin B1, as well as its biosynthetic intermediates pyrimidine and thiazole in Arabidopsis samples. The examined panel of Saccharomyces cerevisiae mutants was, when implemented in microbiol. assays, capable of correctly assigning a series of wild-type and thiamin biofortified Arabidopsis plant samples. The assays provide a readily applicable method allowing rapid screening of vitamin B1 (and its biosynthetic intermediates) content in plant material, which is particularly useful in metabolic engineering approaches and in germplasm screening across or within species. This study involved multiple reactions and reactants, such as (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7SDS of cas: 54-47-7).

(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.SDS of cas: 54-47-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A novel panel of yeast assays for the assessment of thiamin and its biosynthetic intermediates in plant tissues was written by Strobbe, Simon;Verstraete, Jana;Fitzpatrick, Teresa B.;Faustino, Maria;Lourenco, Tiago F.;Oliveira, M. Margarida;Stove, Christophe;Van Der Straeten, Dominique. And the article was included in New Phytologist in 2022.HPLC of Formula: 54-47-7 The following contents are mentioned in the article:

Thiamin (or thiamine), known as vitamin B1, represents an indispensable component of human diets, being pivotal in energy metabolism Thiamin research depends on adequate vitamin quantification in plant tissues. A recently developed quant. liquid chromatog.-tandem mass spectrometry (LC-MS/MS) method is able to assess the level of thiamin, its phosphorylated entities and its biosynthetic intermediates in the model plant Arabidopsis thaliana, as well as in rice. However, their implementation requires expensive equipment and substantial tech. expertise. Microbiol. assays can be useful in deter-mining metabolite levels in plant material and provide an affordable alternative to MS-based anal. Here, we evaluate, by comparison to the LC-MS/MS reference method, the potential of a carefully chosen panel of yeast assays to estimate levels of total vitamin B1, as well as its biosynthetic intermediates pyrimidine and thiazole in Arabidopsis samples. The examined panel of Saccharomyces cerevisiae mutants was, when implemented in microbiol. assays, capable of correctly assigning a series of wild-type and thiamin biofortified Arabidopsis plant samples. The assays provide a readily applicable method allowing rapid screening of vitamin B1 (and its biosynthetic intermediates) content in plant material, which is particularly useful in metabolic engineering approaches and in germplasm screening across or within species. This study involved multiple reactions and reactants, such as (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7HPLC of Formula: 54-47-7).

(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. HPLC of Formula: 54-47-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Loss of a pyridoxal-phosphate phosphatase rescues arabidopsis lacking an endoplasmic reticulum ATP carrier was written by Altensell, Jacqueline;Wartenberg, Ruth;Haferkamp, Ilka;Hassler, Sebastian;Scherer, Vanessa;Steensma, Priscille;Fitzpatrick, Teresa B.;Sharma, Anurag;Sandoval-Ibanez, Omar;Pribil, Mathias;Lehmann, Martin;Leister, Dario;Kleine, Tatjana;Neuhaus, H. Ekkehard. And the article was included in Plant Physiology in 2022.Product Details of 54-47-7 The following contents are mentioned in the article:

The endoplasmic reticulum (ER)-located ATP/ADP-antiporter (ER-ANT1) occurs specifically in vascular plants. Structurally different transporters mediate energy provision to the ER, but the cellular function of ER-ANT1 is still unknown. Arabidopsis (Arabidopsis thaliana) mutants lacking ER-ANT1 (er-ant1 plants) exhibit a photorespiratory phenotype accompanied by high glycine levels and stunted growth, pointing to an inhibition of glycine decarboxylase (GDC). To reveal whether it is possible to suppress this marked phenotype, we exploited the power of a forward genetic screen. Absence of a so far uncharacterized member of the HaloAcid Dehalogenase (HAD)-like hydrolase family strongly suppressed the dwarf phenotype of er-ant1 plants. Localization studies suggested that the corresponding protein locates to chloroplasts, and activity assays showed that the enzyme dephosphorylates, with high substrate affinity, the B6 vitamer pyridoxal 5′-phosphate (PLP). Addnl. physiol. experiments identified imbalances in vitamin B6 homeostasis in er-ant1 mutants. Our data suggest that impaired chloroplast metabolism, but not decreased GDC activity, causes the er-ant1 mutant dwarf phenotype. We present a hypothesis, setting transport of PLP by ER-ANT1 and chloroplastic PLP dephosphorylation in the cellular context. With the identification of this HAD-type PLP phosphatase, we also provide insight into B6 vitamer homeostasis. This study involved multiple reactions and reactants, such as (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7Product Details of 54-47-7).

(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Product Details of 54-47-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Deflagration synthesis of nitrogen/fluorine co-doped hollow carbon nanoparticles with excellent oxygen reduction performance was written by Liu, Yousong;Huang, Bing;Peng, Shengjie;Wang, Tao;Ji, Guangbin;Yang, Guangcheng;Ramakrishna, Seeram. And the article was included in Inorganic Chemistry Frontiers in 2018.Application of 700-16-3 The following contents are mentioned in the article:

Critical factors such as doping content, electronic conductivity and porosity need to be addressed to obtain excellent oxygen reduction reaction (ORR) performance with metal-free carbon-based materials. However, creating a facile approach to obtain carbon materials with a high doping level, high graphitization degree and high surface area still remains a great challenge. In this work, we develop a NaN₃/C₅F₅N deflagration method to synthesize high N/F co-doped carbon hollow nanospheres (N/F-HC) with a high graphitization degree. The deflagration of NaN₃ can produce Na nanoclusters, which can not only capture partial F atoms from C₅F₅N but can also be used as templates for the formation of a hollow structure. The heat liberation from deflagration and the subsequent F-capturing reaction could generate an extremely high temperature for graphitic structure formation. Moreover, the ultra-fast deflagration and F-capturing reaction allow carbon growth to be completed in seconds, which can ensure a high N/F doping content. The optimized N/F-HC catalyst exhibits superior ORR performance with long-term stability compared to a com. Pt/C electrocatalyst in an alk. medium. The synthetic strategy described in this work is facile and is expected to underpin future research efforts to develop metal-free electrocatalysts for the ORR and other applications. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Loss of a pyridoxal-phosphate phosphatase rescues Arabidopsis lacking an endoplasmic reticulum ATP carrier. was written by Altensell, Jacqueline;Wartenberg, Ruth;Haferkamp, Ilka;Hassler, Sebastian;Scherer, Vanessa;Steensma, Priscille;Fitzpatrick, Teresa B;Sharma, Anurag;Sandoval-Ibañez, Omar;Pribil, Mathias;Lehmann, Martin;Leister, Dario;Kleine, Tatjana;Neuhaus, H Ekkehard. And the article was included in Plant physiology in 2022.COA of Formula: C8H10NO6P The following contents are mentioned in the article:

The endoplasmic reticulum (ER)-located ATP/ADP-antiporter (ER-ANT1) occurs specifically in vascular plants. Structurally different transporters mediate energy provision to the ER, but the cellular function of ER-ANT1 is still unknown. Arabidopsis (Arabidopsis thaliana) mutants lacking ER-ANT1 (er-ant1 plants) exhibit a photorespiratory phenotype accompanied by high glycine levels and stunted growth, pointing to an inhibition of glycine decarboxylase (GDC). To reveal whether it is possible to suppress this marked phenotype, we exploited the power of a forward genetic screen. Absence of a so far uncharacterized member of the HaloAcid Dehalogenase (HAD)-like hydrolase family strongly suppressed the dwarf phenotype of er-ant1 plants. Localization studies suggested that the corresponding protein locates to chloroplasts, and activity assays showed that the enzyme dephosphorylates, with high substrate affinity, the B6 vitamer pyridoxal 5′-phosphate (PLP). Additional physiological experiments identified imbalances in vitamin B6 homeostasis in er-ant1 mutants. Our data suggest that impaired chloroplast metabolism, but not decreased GDC activity, causes the er-ant1 mutant dwarf phenotype. We present a hypothesis, setting transport of PLP by ER-ANT1 and chloroplastic PLP dephosphorylation in the cellular context. With the identification of this HAD-type PLP phosphatase, we also provide insight into B6 vitamer homeostasis. This study involved multiple reactions and reactants, such as (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7COA of Formula: C8H10NO6P).

(4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate (cas: 54-47-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.COA of Formula: C8H10NO6P

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hydrogen Bond Directed Photocatalytic Hydrodefluorination: Overcoming Electronic Control was written by Khaled, Mohammad B.;El Mokadem, Roukaya K.;Weaver, Jimmie D.. And the article was included in Journal of the American Chemical Society in 2017.Category: pyridine-derivatives The following contents are mentioned in the article:

The photocatalytic C-F functionalization of highly fluorinated arenes is a powerful method for accessing functionalized multifluorinated arenes. The decisive step in the determining regioselectivity in fluorine functionalization is fluoride fragmentation from the radical anion of the multifluorinated arene. To date, the availability of regioisomers has been dictated by the innate electronics of the fluorinated arene, limiting the synthetic utility of the chem. This study investigates the remarkable ability of a strategically located hydrogen bond to transcend the normal regioselectivity of the C-F functionalization event. A significant rate acceleration is addnl. observed for hydrodefluorination of fluorines that can undergo intramol. hydrogen bonds that form 5-8-membered cycles with moderately acidic N-H’s. The hydrogen bond is expected to facilitate the fragmentation not only by bending the C-F bond of the radical anion out of planarity but also by increasing the exothermicity of the fluoride extrusion step through protonation of the naked fluoride. Finally, the synthetic utility of the method is demonstrated in an expedited synthesis of the trifluorinated α-Ph acetic acid derivative required for the com. synthesis of Januvia, an antidiabetic drug. This represents the first synthesis of a com. important multifluorinated arene via a defluorination strategy and is significantly shorter than the current strategy. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Category: pyridine-derivatives).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem