Day: December 30, 2022

Lima, Filipe S. et al. published their research in Langmuir in 2015 | CAS: 104-73-4

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Category: pyridine-derivatives

Sodium triflate decreases interaggregate repulsion and induces phase separation in cationic micelles was written by Lima, Filipe S.;Cuccovia, Iolanda M.;Buchner, Richard;Antunes, Filipe E.;Lindman, Bjorn;Miguel, Maria G.;Horinek, Dominik;Chaimovich, Hernan. And the article was included in Langmuir in 2015.Category: pyridine-derivatives This article mentions the following:

Dodecyltrimethylammonium triflate (DTATf) micelles possess lower degree of counterion dissociation (α), lower hydration, and higher packing of monomers than other micelles of similar structure. Addition of sodium triflate ([NaTf] > 0.05 M) to DTATf solutions promotes phase separation This phenomenon is commonly observed in oppositely charged surfactant mixtures, but it is rare for ionic surfactants and relatively simple counterions. While the properties of DTATf have already been reported, the driving forces for the observed phase separation with added salt remain unclear. Thus, we propose an interpretation for the observed phase separation in cationic surfactant solutions Addition of up to 0.03 M NaTf to micellar DTATf solutions led to a limited increase of the aggregation number, to interface dehydration, and to a progressive decrease in α. The viscosity of DTATf solutions of higher concentration ([DTATf] ≥ 0.06 M) reached a maximum with increasing [NaTf], though the aggregation number slightly increased, and no shape change occurred. We hypothesize that this maximum results from a decrease in interaggregate repulsion, as a consequence of increased ion binding. This reduction in micellar repulsion without simultaneous infinite micellar growth is, probably, the major driving force for phase separation at higher [NaTf]. In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Category: pyridine-derivatives).

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhou, Bo et al. published their research in Angewandte Chemie, International Edition in 2019 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Application of 626-64-2

Simultaneous Long-Persistent Blue Luminescence and High Quantum Yield within 2D Organic-Metal Halide Perovskite Micro/Nanosheets was written by Zhou, Bo;Yan, Dongpeng. And the article was included in Angewandte Chemie, International Edition in 2019.Application of 626-64-2 This article mentions the following:

Mol. solid-state materials with long-lived luminescence (such as thermally activated delayed fluorescence (TADF) and room temperature phosphorescence (RTP) systems) are promising for display, sensoring, and bio-imaging applications. However, the design of such materials that exhibit both long luminescent lifetime and high solid-state emissive efficiency remains an open challenge. Two-dimensional (2D) organic-metal halide perovskite materials have a high blue-emitting quantum yield of up to 63.55 % and ultralong TADF lifetime of 103.12 ms at ambient temperature and atm. Our design leverages the combined influences of a 2D space/electronic confinement effect and a modest heavy-atom tuning strategy. Photophys. studies and calculations reveal that the enhanced quantum yield is due to the rigid laminate structure of perovskites, which can effectively inhibit the non-radiative decay of excitons. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Application of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Naz, Sadia et al. published their research in ChemistrySelect in 2022 | CAS: 125652-55-3

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.SDS of cas: 125652-55-3

Ionic Liquids Mediated One-Pot Synthesis of Second Generation 5-Ethoxymethylfurfural (5-EMF); A Potent Biofuel Candidate was written by Naz, Sadia;Uroos, Maliha. And the article was included in ChemistrySelect in 2022.SDS of cas: 125652-55-3 This article mentions the following:

5-Ethoxymethylfurfural (5-EMF) is a promising fuel alternative and biofuel additive due to its high energy potential. Principal method for its synthesis is etherification of hydroxyl group of 5-hydroxymethylfurfural (5-HMF), produced by the dehydration of fructose. Currently existing methods for the synthesis of 5-EMF are not industrially feasible due to the issues associated with their starting materials; either they are highly expensive (such as 5-HMF), or compete with food (sugars such as fructose and glucose). Herein, we are reporting a one-pot protocol for the synthesis of 5-EMF using non-food indigenous agricultural waste material, thus completely eliminating the both issues. Cost is also very much reduced due to the utilization of cheap pyridinium based ionic liquids Energy, time and solvents use is also reduced, as reaction is happening in a single pot. The process is optimized first for fructose (73% 5-EMF yield) and glucose (16% 5-EMF), and was then extended for real biopolymeric cellulose (16% 5-EMF) and wheat husk biomass (15% 5-EMF). Product was characterized via HPLC and 1HNMR spectroscopy. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3SDS of cas: 125652-55-3).

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.SDS of cas: 125652-55-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kubota, Tanekazu et al. published their research in Journal of the American Chemical Society in 1968 | CAS: 3718-65-8

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives

Electron spin resonance and polarographic studies of the anion radicals of heterocyclic amine N-oxide was written by Kubota, Tanekazu;Nishikida, Koichi;Miyazaki, Hiroshi;Iwatani, Kouji;Oishi, Yoshiko. And the article was included in Journal of the American Chemical Society in 1968.Category: pyridine-derivatives This article mentions the following:

Polarograms of 30 heterocyclic amine N-oxide were recorded in HCONMe2 at ∼25°. E.S.R. spectra of radical anions formed during controlled-potential electrolysis at the potential corresponding to the first reduction wave were observed for 16 of the oxide. The hydrogen (aH) and nitrogen (aN) hyperfine coupling constants were determined by the method of spectral simulation. With 4-cyano- and 4-nitropyridine N-oxide anion radicals, D substitution was used to confirm the anal. Hueckel M.O. calculations with the McLachlan modification, where the necessary parameters were chosen to give agreement with the αH’s of pyrazine N,N’-dioxide, 4-cyanopyridine N-oxide, and pyrazine mono-N-oxide, yielded the following linear relations between calculated spin density, ρ, and exptl. coupling constant for the compounds studied: αH = -25.7σc and aN = 42.6ρN – 6.7(ρc + ρc’) – 19.0ρo. Also, using fewer parameters, αN was satisfactorily expressed by aN = 41.9ρN – 2.1. In addition, E.S.R. spectra of the anion radicals of pyridine N-oxide and its 2,6-dideuterio derivative were observed during electrolysis in liquid NH3. The comparison of the αH’s and aN so observed with the calculated values using the equations above was in good agreement. Also the polarographic data were analyzed in terms of radical stability and were related to the E.S.R. results as follows. The peak height of the a.c. polarogram and the half-wave potential (E1/2) of the first reduction wave are approx. linearly related to the radical stability. Moreover, the E1/2 is in linear relation with the lowest vacant M.O. energy (εLV) and also with the Hammett σ value of a series of substituted pyridine N-oxide. Thus, E1/2 = 2.75εLV – 0.77 and – E1/2 = 1.08σ – 2.19. The results are compared with those of related compounds reported in the literature. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Category: pyridine-derivatives).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bocian, Aleksandra et al. published their research in Journal of Molecular Liquids in 2020 | CAS: 91-02-1

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Quality Control of Phenyl(pyridin-2-yl)methanone

New benzothiazole based copper(II) hydrazone Schiff base complexes for selective and environmentally friendly oxidation of benzylic alcohols: The importance of the bimetallic species tuned by the choice of the counterion was written by Bocian, Aleksandra;Gorczynski, Adam;Marcinkowski, Damian;Witomska, Samanta;Kubicki, Maciej;Mech, Paulina;Bogunia, Malgorzata;Brzeski, Jakub;Makowski, Mariusz;Pawluc, Piotr;Patroniak, Violetta. And the article was included in Journal of Molecular Liquids in 2020.Quality Control of Phenyl(pyridin-2-yl)methanone This article mentions the following:

Green and sustainable chem. approaches necessitate an ongoing investigation toward new, environmentally benign and selective catalysts. The authors have thus prepared a new benzothiazole-scaffold hydrazone Schiff base ligand L and coordinated it with copper(II) ions leading to five different complexes, the form of which in the solid state is counterion-dependent. Nitrate, chloride and triflate anions lead to monometallic species, whereas utilization of sulfates and tetrafluoroborates is responsible for the formation of bimetallic assemblies. The catalytic efficiency of synthesized compounds was shown in Cu-TEMPO (2,2,6,6-tetramethyl-l-piperidinoxyl) aerobic oxidation of activated alcs. resulting in good to excellent conversions and 100% selectivity to form the corresponding aldehydes. Considering the exptl. results and d. functional theory calculations we propose two most plausible reaction mechanisms that further corroborate the enhanced activity of bimetallic species. It appears that the tridentate character of the ligand sacrifices some of the overall catalytic efficiency for the selectivity of the process. Aqueous reaction medium, low catalyst loading, air as oxidant and exclusive oxidative selectivity render these CuII complexes promising candidates for further improvement. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Quality Control of Phenyl(pyridin-2-yl)methanone).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Quality Control of Phenyl(pyridin-2-yl)methanone

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lin, Hongyan et al. published their research in Journal of Coordination Chemistry in 2011 | CAS: 15420-02-7

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Computed Properties of C12H8N4O

Syntheses, crystal structures, and electrochemical properties of two cobalt complexes constructed with benzene tricarboxylates and 2,5-bis(pyridyl)-1,3,4-oxadiazole was written by Lin, Hongyan;Mu, Bao;Wang, Xiuli. And the article was included in Journal of Coordination Chemistry in 2011.Computed Properties of C12H8N4O This article mentions the following:

Two new Co complexes based on benzene tricarboxylates 1,2,4-H3BTC (1,2,4-H3BTC = 1,2,4-benzenetricarboxylate) or 1,3,5-H3BTC (1,3,5-H3BTC = 1,3,5-benzenetricarboxylate), and the bent dipyridyl ligand 2,5-bis(3-pyridyl)-1,3,4-oxadiazole (3-bpo) or its 4-pyridyl N-donor analog 2,5-bis(4-pyridyl)-1,3,4-oxadiazole (4-bpo), formulated as [Co(1,3,5-BTC)(4-bpo)(H2O)3]2[Co(H2O)6]·10H2O (1) and [Co3(1,2,4-BTC)2(3-bpo)2(H2O)12] (2), were hydrothermally synthesized and characterized by elemental analyses, IR spectroscopy, TG analyses, and single-crystal x-ray diffraction. Structure anal. reveals that 1 is a 3-dimensional porous supramol. network based on the 1-dimensional polymer chain, in which discrete [Co(H2O)6]2+ units and lattice H2O mols. are dispersed. In 2, bridging 3-bpo and 1,2,4-BTC ligands connect cobalt ions to form a trinuclear Co unit. Adjacent trinuclear Co units are further linked by π-π stacking interactions and H-bonding interactions to form a 3-dimensional supramol. framework. Electrochem. properties of Co(II) compounds as bulk-modified carbon paste electrodes (1-CPE and 2-CPE) were studied. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Computed Properties of C12H8N4O).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Computed Properties of C12H8N4O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yang, Jialin et al. published their research in Tetrahedron Letters in 2015 | CAS: 644-98-4

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Product Details of 644-98-4

Asymmetrical synthesis of fluorinated 2-(pyridin-2-yl) alkylamine from fluoromethyl sulfinyl imines and 2-alkylpyridines was written by Yang, Jialin;Zhang, Jiali;Meng, Weidong;Huang, Yangen. And the article was included in Tetrahedron Letters in 2015.Product Details of 644-98-4 This article mentions the following:

A novel strategy was developed to synthesize fluorinated 2-(pyridin-2-yl) alkylamines via condensation of 2-alkylpyridines and chiral fluoromethyl N-tert-Bu sulfinyl imines with good diastereo-control and good chem. yields. The chiral N-tert-Bu sulfinyl auxiliary can be easily removed under mild acidic condition at room temperature The application of this strategy was demonstrated in the synthesis of a fluorine-containing pesticide candidate. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Product Details of 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Product Details of 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yuan, Chuan et al. published their research in Energy (Oxford, United Kingdom) in 2019 | CAS: 626-64-2

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Safety of Pyridin-4-ol

Optimization of hydrothermal co-liquefaction of seaweeds with lignocellulosic biomass: Merging 2nd and 3rd generation feedstocks for enhanced bio-oil production was written by Yuan, Chuan;Wang, Shuang;Cao, Bin;Hu, Yamin;Abomohra, Abd El-Fatah;Wang, Qian;Qian, Lili;Liu, Lu;Liu, Xinlin;He, Zhixia;Sun, Chaoqun;Feng, Yongqiang;Zhang, Bo. And the article was included in Energy (Oxford, United Kingdom) in 2019.Safety of Pyridin-4-ol This article mentions the following:

The present work aimed to explore the optimized conditions of hydrothermal co-liquefaction (co-HTL) of the green seaweed “Enteromorpha clathrata (EN)” and the lignocellulosic agricultural waste “rice husk (RH)”. Sep. hydrothermal liquefaction (HTL) of EN and RH showed bio-oil yields of 26.0% and 45.6%, resp. However, co-HTL under optimized conditions showed significant increase in the bio-oil yield by 71.7% over that of EN, and insignificant difference with that of RH. Nevertheless, the conversion ratio of co-HTL showed 10.6% significant increase over that of RH. GC-MS results showed that main compounds of EN and RH bio-oil lump into the C15-C20 and C5-C12 regions, mainly representing carbon range of diesel and gasoline, resp. Short-chain (C5-C12) and long-chain (C14-C20) compounds in the bio-oil obtained by co-HTL represented 72% and 28%, resp. In addition, the ratio of aromatic compounds in the bio-oil of RH was reduced by 9.3% as a result of co-HTL. In conclusion, results suggested 50% ethanol as a co-solvent, 300°C and 45 min as optimum conditions for co-HTL of EN:RH (1:1 weight/weight). The present study demonstrated an efficient route for co-HTL of 3rd generation feedstocks with 2nd generation feedstocks which will have a significant impact on large-scale applications. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Safety of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Safety of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Broering, Martin et al. published their research in Inorganica Chimica Acta in 2007 | CAS: 823-61-0

3,6-Dimethyl-2-pyridinamine (cas: 823-61-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Name: 3,6-Dimethyl-2-pyridinamine

Palladium complexes of sterically hindered meridonal tridentate NNN ligands was written by Broering, Martin;Kleeberg, Christian. And the article was included in Inorganica Chimica Acta in 2007.Name: 3,6-Dimethyl-2-pyridinamine This article mentions the following:

Pd(bai)(OAc) (Hbai = new 1,3-bis(arylimino)isoindoline ligands, 1,3-bis(3,6-dimethylpyridylimino)-α,α’-dimethoxyisoindoline H(3,6-MepMeOi) (5) and 1,3-bis(4-methyl-5-isopropylthiazolylimino)isoindoline H(iPrbti) (6)) were prepared from com. precursors and Pd(OAc)2 in 4 and 3 steps, resp. Pd(bai)(OAc) 7 and 8, resp., were characterized by 1H and 13C NMR spectroscopy and mass spectrometry and could be further studied by single crystal x-ray diffraction studies. The mol. structures of 7·2CHCl3 and 8 show differences in the conformational fine-tuning and unravel a higher degree of similarity with related tripyrrinates for the bti derivative 8 than for the bpi species 7. In the experiment, the researchers used many compounds, for example, 3,6-Dimethyl-2-pyridinamine (cas: 823-61-0Name: 3,6-Dimethyl-2-pyridinamine).

3,6-Dimethyl-2-pyridinamine (cas: 823-61-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Name: 3,6-Dimethyl-2-pyridinamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Jing et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2018 | CAS: 4783-68-0

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Product Details of 4783-68-0

Nickel-catalyzed C-O bond reduction of aryl and benzyl 2-pyridyl ethers was written by Li, Jing;Wang, Zhong-Xia. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2018.Product Details of 4783-68-0 This article mentions the following:

The reduction of aryl and benzyl 2-pyridyl ethers with sodium isopropoxide was carried out via nickel-catalyzed C-OPy bond cleavage, giving reductive products in reasonable to excellent yields. This method allowed the 2-pyridyloxy group to be directly removed with high efficiency, mild reaction conditions, and good compatibility of functional groups. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Product Details of 4783-68-0).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Product Details of 4783-68-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem