Day: December 30, 2022

Parallel microwave-assisted synthesis of ionic liquids and screening for denitrogenation of straight-run diesel feed by liquid-liquid extraction was written by Ceron, Miguel A.;Guzman-Lucero, Diego J.;Palomeque, Jorge F.;Martinez-Palou, Rafael. And the article was included in Combinatorial Chemistry & High Throughput Screening in 2012.Related Products of 65350-59-6 This article mentions the following:

Fifty-six ionic liquids were efficiently synthesized in parallel format under one-pot, solvent-free microwave-assisted synthesis. These compounds were evaluated as extracting agents of nitrogen-containing compounds from a real Diesel feed before being submitted to the hydrodesulfurization process to obtain ultralow sulfur Diesel. Our results showed that halogenated ionic liquids are an excellent alternative due to these ionic liquids are relatively inexpensive, presenting a high selectivity for the extraction of nitrogen-containing compounds and can be regenerated and recycled. In the experiment, the researchers used many compounds, for example, 1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6Related Products of 65350-59-6).

1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Related Products of 65350-59-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Side reactions during preparation and handling of oligomers and polymers from 2-vinylpyridine was written by Schmitz, F. P.;Hilgers, H.;Gemmel, B.. And the article was included in Makromolekulare Chemie in 1990.SDS of cas: 644-98-4 This article mentions the following:

Side reactions occurring during the polymerization and oligomerization of vinylpyridine were discussed, and some of them evidenced by experiments The occurrence of ring substitution at the pyridine ring was demonstrated by model reactions. In addition, chain rearrangement in solution was observed From the exptl. results conclusions are drawn for the choice of the appropriate conditions for preparation and handling of polymers and oligomers of vinylpyridine. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4SDS of cas: 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. SDS of cas: 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Palladium-Catalyzed Direct C(sp²)-H Alkoxylation of 2-Aryloxypyridines Using 2-Pyridyloxyl as the Directing Group was written by Zhang, Chun;Sun, Peipei. And the article was included in Journal of Organic Chemistry in 2014.SDS of cas: 4783-68-0 This article mentions the following:

An efficient and highly regioselective palladium-catalyzed ortho-C(sp²)-H bond alkoxylation of 2-aryloxypyridines was developed using 2-pyridyloxyl as the directing group and alcs. as alkoxylation reagents. Under an air atm. and in the presence of PhI(OAc)₂, the reaction gave the corresponding products in moderate to good yields, and a series of functional groups could be tolerated. E.g., in the presence of Pd(OAc)₂ and PhI(OAc)₂, regioselective alkoxylation of 2-aryloxypyridine derivative (I) with MeOH gave 58% II. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0SDS of cas: 4783-68-0).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.SDS of cas: 4783-68-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles was written by Roy, Patrick J.;Dufresne, Claude;Lachance, Nicolas;Leclerc, Jean-Philippe;Boisvert, Michel;Wang, Zhaoyin;Leblanc, Yves. And the article was included in Synthesis in 2005.Category: pyridine-derivatives This article mentions the following:

A series of substituted 5-, 6-, and 7-azaindoles were prepared via the Hemetsberger-Knittel reaction. In general, better yields were obtained at higher temperatures and shorter reaction times than required for the formation of the analogous indoles, and in some cases, only decomposition occurred below a min. temperature The resulting templates offer up to five sites for subsequent functionalization to allow a wide range of chem. diversity. In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1Category: pyridine-derivatives).

2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Poly(1,3,4-oxadiazoles). IV. Poly(1,3,4-oxadiazoles) containing pyridine rings was written by Iwakura, Yoshio;Uno, Keikichi;Hara, Shigeyoshi. And the article was included in Makromolekulare Chemie in 1967.SDS of cas: 15420-02-7 This article mentions the following:

Poly(1,3,4-oxadiazoles), which have both thermostability and solubility in organic solvents, are formed by the polycondensation of pyridine dicarboxylic dihydrazides in fuming H2SO4 or polyphosphoric acid (I). The resulting polymers contain pyridine rings and have low mol. weight Thus, 4 g. isocinchomeronic dihydrazide was dissolved with gradual heating in 60 g. I. Heating was continued for 2 hrs. at 120° and 6 hrs. at 180°. The mixture turned dark brown in color. The product was precipitated and washed in H2O, allowed to stand overnight in dilute Na2CO3 solution, H2O-washed, and vacuum dried at 70° to yield 3.2 g. poly(pyridine-5,2-diyl-1,3,4-oxadiazole-2,5-diyl) (II), sp. viscosity 0.16 (0.2 g./100 ml. 95% H2SO4, 30°). [TABLE OMITTED] Similar polymers were prepared from the solution polycondensation of dinicotinic, 2,6-dimethyldinicotinic, dipicolinic, and dipicolinic terephthalic dihydrazides. Polycondensation in fuming H2SO4 gave considerably lower yields. Differences were observed between the ir spectrum of II and that of authentic II prepared by the cyclodehydration of poly(isocinchomeronic hydrazide) in fuming H2SO4. The ir spectrum of II relatively agreed with that of a model compound, 2,5-di-3-pyridyl-1,3,4-oxadiazole, m. 185-5.5°, prepared by condensing nicotinic acid with hydrazine sulfate in fuming H2SO4. Another model compound, 2,5-di-4-pyridyl-1,3,4-oxadiazole, m. 184.5-5°, was similarly prepared from isonicotinic acid. Brittle films of the various polymers were cast from ClCHCO2H and showed moderate solubility in H2SO4 and HCO2H. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7SDS of cas: 15420-02-7).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. SDS of cas: 15420-02-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ionic liquids – reaction media and catalysts for synthesis of 1,4-dihydropyridines was written by Zicmanis, A.;Hinica, A.;Pavlovica, S.;Klavins, M.. And the article was included in Latvijas Kimijas Zurnals in 2009.Application In Synthesis of 1-Dodecylpyridin-1-ium bromide This article mentions the following:

Ionic liquids (ILs) were evaluated as tunable solvents for the Hantzsch synthesis of 1,4-dihydropyridines (DHP) from 1,3-dicarbonyl compounds and hexamethylenetetramine. Structure changes of both cations and anions in ionic liquids allow design of the most suitable structure for the particular DHP synthesis. Increasing the hydrophobicity of the cation in the IL results in decreased yield of DHP; aromatic and aliphatic cations show similar performance; aromatic anions are slightly better than aliphatic ones; and more nucleophilic anions provide higher yield than other anions. Addition of buffer substances to the reaction mixture has a clearly pos. impact on the yield of DHP. Increased temperature results in higher yields of DHP. In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Application In Synthesis of 1-Dodecylpyridin-1-ium bromide).

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Application In Synthesis of 1-Dodecylpyridin-1-ium bromide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Iridium-Catalyzed Intermolecular Asymmetric Allylic Amination with Pyridones was written by Tu, Hang-Fei;Nie, Yu-Han;Zheng, Chao;You, Shu-Li. And the article was included in Advanced Synthesis & Catalysis in 2022.Product Details of 626-64-2 This article mentions the following:

Herein a catalytic synthetic method for enantioenriched N-substituted pyridones was reported. By employing chiral iridium catalyst generated from the Carreira [P/olefin] ligand, intermol. asym. allylic amination of allyl alcs. with pyridones proceeded smoothly with excellent chemo-, regio- and enantioselectivities (>19:1 N/O, >19:1 b/l and ≥89% ee). The reaction was a kinetic resolution process under mild conditions and displayed a broad substrate scope for both pyridones and allylic alcs. The potential of this method was demonstrated by a gram-scale reaction with only 0.6 mol% catalyst loading and diverse transformations of the amination products to useful skeletons. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Product Details of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Product Details of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lewis acid-catalyzed regioselective C-H carboxamidation of indolizines with dioxazolones via an acyl nitrene type rearrangement was written by Song, Dan;Huang, Changfeng;Liang, Peishi;Zhu, Baofu;Liu, Xiang;Cao, Hua. And the article was included in Organic Chemistry Frontiers in 2021.Product Details of 24103-75-1 This article mentions the following:

An efficient, direct, and novel Lewis acid-catalyzed regioselective C-H carboxamidation of indolizines with dioxazolones via an acyl nitrene type rearrangement under metal-free conditions was documented. A diverse array of indolizine-3-carboxamides I [R = Ph, 4-MeC₆H₄, 2-naphthyl, etc.; R¹ = H, 8-Me, 6-Et, etc.; R² = Ph, 4-MeC₆H₄, 2-FC₆H₄, etc.] were achieved in moderate to good yields with wide substrate scope. In these transformations, isocyanatobenzene was formed by the ring opening of dioxazolones and a subsequent Curtius-type rearrangement, which could be harnessed in C-H carboxamidation of N-heterocycles. The present protocol is satisfactorily complementary to nitrene transfer chem. and C-H functionalization of N-heterocycles. Furthermore, photophys. experiments revealed that a few compounds exhibited high fluorescence absorption and emission intensity. In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1Product Details of 24103-75-1).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Product Details of 24103-75-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Binding affinity of pyridines with Am^III/Cm^III elucidated by density functional theory calculations was written by Yu, Jie;Ma, Jun;Yang, Chuting;Yu, Haizhu. And the article was included in Dalton Transactions in 2019.Related Products of 644-98-4 This article mentions the following:

In recent decades, N-heterocyclic ligands have been extensively used in the separation of lanthanides/actinides, whereas the selective extraction of amercium or curium has been very challenging. Using d. functional theory calculations, this study is devoted to the investigation of the binding affinity of a series of modeling pyridine ligands with AmIII and CmIII. The structure-property correlations between the amercium and curium systems and the binding affinity were obtained, and promising strategies for efficient separation of AmIII/CmIII were proposed. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Related Products of 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Related Products of 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Aqueous biphasic systems composed of ionic liquids and sodium carbonate as enhanced routes for the extraction of tetracycline was written by Marques, Carlos F. C.;Mourao, Teresa;Neves, Catarina M. S. S.;Lima, Alvaro S.;Boal-Palheiros, Isabel;Coutinho, Joao A. P.;Freire, Mara G.. And the article was included in Biotechnology Progress in 2013.Safety of 1-Butyl-3-methylpyridinium Chloride This article mentions the following:

Aqueous biphasic systems (ABS) using ionic liquids (ILs) offer an alternative approach for the extraction, recovery, and purification of biomols. through their partitioning between two aqueous liquid phases. In this work, the ability of a wide range of ILs to form ABS with aqueous solutions of Na₂CO₃ was evaluated. The ABS formed by IL + water + Na₂CO₃ were determined at 25°C, and the resp. solubility curves, tie-lines, and tie-line lengths are reported. The studied ILs share the common chloride anion, allowing the IL cation core, the cation isomerism, the presence of functionalized groups, and alkyl side chain length effects to be evaluated. An increase in the cation side alkyl chain length leads to a higher ability for liquid-liquid demixing whereas different positional isomers and the presence of an allyl group have no major influence in the phase diagrams behavior. Quaternary phosphonium- and ammonium-based fluids are more able to form an ABS when compared with imidazolium-, pyridinium-, pyrrolidinium-, and piperidium-based ILs. Moreover, the presence of an aromatic cation core has no major contribution to the formation of ABS when compared to the resp. nonaromatic counterparts. Finally, to appraise on the systems applicability in downstream processing, selected systems were used for the partitioning of tetracyclines (neutral and salt forms) – a class of antibiotics produced by bacteria fermentation Single-step extraction efficiencies for the IL-rich phase were always higher than 99% and confirm the great potential of ILs to be applied in the biotechnol. field. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3Safety of 1-Butyl-3-methylpyridinium Chloride).

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Safety of 1-Butyl-3-methylpyridinium Chloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem