Day: February 9, 2023

Shaabani, Shabnam et al. published their research in Green Chemistry in 2019 | CAS: 628-13-7

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Safety of Pyridinehydrochloride

Automated and accelerated synthesis of indole derivatives on a nano-scale was written by Shaabani, Shabnam;Xu, Ruixue;Ahmadianmoghaddam, Maryam;Gao, Li;Stahorsky, Martin;Olechno, Joe;Ellson, Richard;Kossenjans, Michael;Helan, Victoria;Doemling, Alexander. And the article was included in Green Chemistry in 2019.Safety of Pyridinehydrochloride This article mentions the following:

For the first time use of acoustic droplet ejection technol. and fast quality control was described to screen the efficiency of synthetic reactions on a nanomole scale in an automated and miniaturized fashion. The interrupted Fischer indole combined with Ugi-type reactions yielded several attractive drug-like indole scaffolds such as I [R1 = H, 5-Me, 4,6-di-Me, 5-MeO, 7-Br; R2 = Me, Et, ; R3 = Me, Et; R2R3 = (CH2)5, (CH2)2O(CH2)2, (CH2)2NBoc(CH2)2; R4 = i-Pr, cyclohexyl, 4-MeOC6H4, etc.; R5 = t-Bu, 2-pyrrolyl, 2-indolyl, etc.], tetrazole II and imino hadantoin e.g., III. In 384-well plates, a diverse set of interrupted Fischer indole intermediates were produced and reacted with the tricyclic hydantoin backbone in a 2-step sequence. Similarly, preformed Fischer indole intermediates were used to produce diverse sets of Ugi products and the efficiency was compared with that of the in situ method. Multiple reactions were performed again on a preparative millimole scale, showing scalability from nano to mg and thus synthetic utility. An unprecedented large number of building blocks were used for fast scope and limitation studies (68 isocyanides, 72 carboxylic acids). Miniaturization and anal. of the generated big synthesis data enabled deeper exploration of the chem. space and permitted the gain of knowledge that was previously impractical or impossible, such as the rapid survey of reactions and building block and functional group compatibility. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Safety of Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Safety of Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mukherji, Ananya et al. published their research in Organic Letters in 2020 | CAS: 628-13-7

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.HPLC of Formula: 628-13-7

C-H···Anion Interactions Assisted Addition of Water to Glycals by Sterically Hindered 2,4,6-Tri-tert-butylpyridinium Hydrochloride was written by Mukherji, Ananya;Kancharla, Pavan K.. And the article was included in Organic Letters in 2020.HPLC of Formula: 628-13-7 This article mentions the following:

The conjugate acid of the bulky base 2,4,6-tri-tert-butylpyridine, under mild conditions, catalyzes the synthesis of silyl-protected 2-deoxy-hemiacetals and their dimerized products from glycals at varying concentrations of water. The criticality of the concentration of water in the reaction outcome is indicative of a unique mechanistic pathway for the bulky pyridine salt and not via the general Bronsted acid mechanism. The various silyl-protected hemiacetals thus synthesized were successfully utilized in the stereoselective synthesis of both α and β glycosides. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7HPLC of Formula: 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.HPLC of Formula: 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lounsbury, Nicole et al. published their research in Bioorganic & Medicinal Chemistry in 2015 | CAS: 116308-35-1

2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Recommanded Product: 2-(Trifluoromethyl)nicotinaldehyde

Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy was written by Lounsbury, Nicole;Mateo, George;Jones, Brielle;Papaiahgari, Srinivas;Thimmulappa, Rajash K.;Teijaro, Christiana;Gordon, John;Korzekwa, Kenneth;Ye, Min;Allaway, Graham;Abou-Gharbia, Magid;Biswal, Shyam;Childers, Wayne. And the article was included in Bioorganic & Medicinal Chemistry in 2015.Recommanded Product: 2-(Trifluoromethyl)nicotinaldehyde This article mentions the following:

Nrf2 activators represent a good drug target for designing agents to treat diseases associated with oxidative stress. Building upon previous work, we designed and prepared a series of heterocyclic chalcone-based Nrf2 activators with reduced lipophilicity and, in some cases, greater in vitro potency compared to the resp. carbocyclic scaffold. These changes resulted in enhanced oral bioavailability and a superior pharmacodynamic effect in vivo. In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1Recommanded Product: 2-(Trifluoromethyl)nicotinaldehyde).

2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Recommanded Product: 2-(Trifluoromethyl)nicotinaldehyde

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wang, Guoqiang et al. published their research in Journal of the American Chemical Society in 2017 | CAS: 3939-14-8

2-Fluoroisonicotinonitrile (cas: 3939-14-8) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Formula: C6H3FN2

Metal-Free Synthesis of C-4 Substituted Pyridine Derivatives Using Pyridine-boryl Radicals via a Radical Addition/Coupling Mechanism: A Combined Computational and Experimental Study was written by Wang, Guoqiang;Cao, Jia;Gao, Liuzhou;Chen, Wenxin;Huang, Wenhao;Cheng, Xu;Li, Shuhua. And the article was included in Journal of the American Chemical Society in 2017.Formula: C6H3FN2 This article mentions the following:

D. functional theory investigations revealed that the pyridine-boryl radical generated in situ using 4-cyanopyridine and bis(pinacolato)diboron could be used as a bifunctional “reagent”, which serves as not only a pyridine precursor but also a boryl radical. With the unique reactivity of such radicals, 4-substituted pyridine derivatives could be synthesized using α,β-unsaturated ketones and 4-cyanopyridine via a novel radical addition/C-C coupling mechanism. Several controlled experiments were conducted to provide supportive evidence for the proposed mechanism. In addition to enones, the scope could be extended to a wide range of boryl radical acceptors, including various aldehydes and ketones, aryl imines and alkynones. Lastly, this transformation was applied in the late-stage modification of a complicated pharmaceutical mol. In the experiment, the researchers used many compounds, for example, 2-Fluoroisonicotinonitrile (cas: 3939-14-8Formula: C6H3FN2).

2-Fluoroisonicotinonitrile (cas: 3939-14-8) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Formula: C6H3FN2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bugaenko, Dmitry I. et al. published their research in Organic Letters in 2021 | CAS: 59718-84-2

Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. HPLC of Formula: 59718-84-2

From Pyridine-N-oxides to 2-Functionalized Pyridines through Pyridyl Phosphonium Salts: An Umpolung Strategy was written by Bugaenko, Dmitry I.;Yurovskaya, Marina A.;Karchava, Alexander V.. And the article was included in Organic Letters in 2021.HPLC of Formula: 59718-84-2 This article mentions the following:

The reactions of pyridine-N-oxides with Ph3P under the developed conditions provide an unprecedented route to (pyridine-2-yl)phosphonium salts. Upon activation with DABCO, these salts readily serve as functionalized 2-pyridyl nucleophile equivalent This umpolung strategy allows for the selective C2 functionalization of the pyridine ring with electrophiles, avoiding the generation and use of unstable organometallic reagents. The protocol operated at ambient temperature and tolerated sensitive functional groups, enabling the synthesis of otherwise challenging compounds In the experiment, the researchers used many compounds, for example, Methyl 3-methylpicolinate (cas: 59718-84-2HPLC of Formula: 59718-84-2).

Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. HPLC of Formula: 59718-84-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Trikalitis, Pantelis N. et al. published their research in Microporous and Mesoporous Materials in 2006 | CAS: 104-73-4

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Safety of 1-Dodecylpyridin-1-ium bromide

Mesostructured cobalt and nickel molybdenum sulfides was written by Trikalitis, Pantelis N.;Kerr, Tracy A.;Kanatzidis, Mercouri G.. And the article was included in Microporous and Mesoporous Materials in 2006.Safety of 1-Dodecylpyridin-1-ium bromide This article mentions the following:

The authors report the synthesis of mesostructured cobalt and nickel molybdenum sulfides prepared by reacting MoS42- anions with Co2+ and Ni2+ in formamide solution in the presence of N-alkylpyridinium surfactant mols. acting as template. These systems represent the first examples of templated mesostructured Co-Mo-S and Ni-Mo-S type materials. In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Safety of 1-Dodecylpyridin-1-ium bromide).

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Safety of 1-Dodecylpyridin-1-ium bromide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Focken, Thilo et al. published their research in Journal of Medicinal Chemistry in 2018 | CAS: 116922-60-2

3-Bromo-4-fluoropyridine (cas: 116922-60-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.SDS of cas: 116922-60-2

Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3-a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain was written by Focken, Thilo;Chowdhury, Sultan;Zenova, Alla;Grimwood, Michael E.;Chabot, Christine;Sheng, Tao;Hemeon, Ivan;Decker, Shannon M.;Wilson, Michael;Bichler, Paul;Jia, Qi;Sun, Shaoyi;Young, Clint;Lin, Sophia;Goodchild, Samuel J.;Shuart, Noah G.;Chang, Elaine;Xie, Zhiwei;Li, Bowen;Khakh, Kuldip;Bankar, Girish;Waldbrook, Matthew;Kwan, Rainbow;Nelkenbrecher, Karen;Karimi Tari, Parisa;Chahal, Navjot;Sojo, Luis;Robinette, C. Lee;White, Andrew D.;Chen, Chien-An;Zhang, Yi;Pang, Jodie;Chang, Jae H.;Hackos, David H.;Johnson, J. P.;Cohen, Charles J.;Ortwine, Daniel F.;Sutherlin, Daniel P.;Dehnhardt, Christoph M.;Safina, Brian S.. And the article was included in Journal of Medicinal Chemistry in 2018.SDS of cas: 116922-60-2 This article mentions the following:

The sodium channel NaV1.7 has emerged as a promising target for the treatment of pain based on strong genetic validation of its role in nociception. In recent years, a number of aryl and acyl sulfonamides have been reported as potent inhibitors of NaV1.7, with high selectivity over the cardiac isoform NaV1.5. Herein, we report on the discovery of a novel series of N-([1,2,4]triazolo[4,3-a]pyridin-3-yl)methanesulfonamides as selective NaV1.7 inhibitors. Starting with the crystal structure of an acyl sulfonamide, we rationalized that cyclization to form a fused heterocycle would improve physicochem. properties, in particular lipophilicity. Our design strategy focused on optimization of potency for block of NaV1.7 and human metabolic stability. Lead compounds I (R1 = cPr, R2 = Me), I (R1 = cPr, R2 = cPr) (GNE-131), and II showed excellent potency, good in vitro metabolic stability, and low in vivo clearance in mouse, rat, and dog. Compound I (R1 = cPr, R2 = cPr) also displayed excellent efficacy in a transgenic mouse model of induced pain. In the experiment, the researchers used many compounds, for example, 3-Bromo-4-fluoropyridine (cas: 116922-60-2SDS of cas: 116922-60-2).

3-Bromo-4-fluoropyridine (cas: 116922-60-2) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.SDS of cas: 116922-60-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Idzik, Tomasz J. et al. published their research in Organic Letters in 2019 | CAS: 13472-81-6

3,5-Dibromo-2-hydroxypyridine (cas: 13472-81-6) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. COA of Formula: C5H3Br2NO

Magnesiate-Utilized/Benzyne-Mediated Approach to Indenopyridones from 2-Pyridones: An Attempt To Synthesize the Indenopyridine Core of Haouamine was written by Idzik, Tomasz J.;Borzyszkowska-Ledwig, Aleksandra;Struk, Lukasz;Sosnicki, Jacek G.. And the article was included in Organic Letters in 2019.COA of Formula: C5H3Br2NO This article mentions the following:

An efficient, short-staged synthesis of cis-fused indeno[2,1-b]- and indeno[1,2-c]pyridin-2-ones, starting from 2-pyridones, using magnesiates of type R3MgLi as nucleophilic and deprotonation agents, mediated by benzyne generated in situ, under optimized conditions, is described. Following the developed protocol, rare C4a-aryl substituted indeno[2,1-b]pyridones (e.g. I), resembling the core of haouamine, were obtained. The protocol offering the one-pot synthesis directly from 2-pyridone is also described. In the experiment, the researchers used many compounds, for example, 3,5-Dibromo-2-hydroxypyridine (cas: 13472-81-6COA of Formula: C5H3Br2NO).

3,5-Dibromo-2-hydroxypyridine (cas: 13472-81-6) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. COA of Formula: C5H3Br2NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Han, Ying-Feng et al. published their research in Dalton Transactions in 2010 | CAS: 15420-02-7

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Category: pyridine-derivatives

Self-assembled half-sandwich Ir, Rh-based organometallic molecular boxes for reversible trapping of halocarbon molecules was written by Han, Ying-Feng;Fei, Yue;Jin, Guo-Xin. And the article was included in Dalton Transactions in 2010.Category: pyridine-derivatives This article mentions the following:

Reactions of [Cp*MCl(μ-Cl)]2 (M = Ir or Rh) with 6,11-dihydroxy-5,12-naphthacenedione (H2DHNA) in the presence of a base, gave the corresponding binuclear complexes [Cp*2M2(μ-DHNA)Cl2] (M = Ir (1a); M = Rh (1b)), resp. Treatment of 1a or 1b with bidentate ligands (L) such as pyrazine, 4,4′-dipyridine (bpy), E-1,2-bis(4-pyridyl)ethene (bpe) or 2,5-bis(4-pyridyl)-1,3,5-oxadiazole (bpo) in the presence of AgOTf (OTf = CF3SO3) in MeOH, gave the corresponding tetranuclear complexes, [Cp*4M4(μ-DHNA)2(μ-L)2](OTf)4 (M = Ir, L = pyrazine (3a), bpy (4a), bpe (5a), bpo (6a); M = Rh , L = pyrazine (3b), bpy (4b), bpe (5b), bpo (6b)), resp. X-ray analyses of 3a, 3b, 4a, 4b, 5a and 5b revealed that each of the half-sandwich metal centers was connected by DHNA and bidentate bridging ligands to construct a rectangular cavity with different dimensions, and strong π-π interactions between independent mols. to form rectangular channels in the solid-state. Complexes 3a and 3b based on H2DHNA and pyrazine spacing ligands exhibit selective and reversible small organic mols. adsorption properties. Intercalated supramol. arrays were obtained by introducing Cl2C:CCl2 templates into the middle of the 1-dimensional lines of 3b. The 2-dimensional framework was stabilized due to weak C-H···Cl interactions and the displaced face-to-face π···π interactions between the planes of the monomeric complexes. The hollow cavities in the 2-dimensional frameworks still exhibit selective and reversible CH2Cl2 adsorption properties. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Category: pyridine-derivatives).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kassanova, Assiya Zh. et al. published their research in Synthesis in 2016 | CAS: 4373-61-9

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Quality Control of 2-(m-Tolyl)pyridine

A Novel Convenient Synthesis of Pyridinyl and Quinolinyl Triflates and Tosylates via One-Pot Diazotization of Aminopyridines and Aminoquinolines in Solution was written by Kassanova, Assiya Zh.;Krasnokutskaya, Elena A.;Beisembai, Perizat S.;Filimonov, Victor D.. And the article was included in Synthesis in 2016.Quality Control of 2-(m-Tolyl)pyridine This article mentions the following:

The first effective and simple method for the direct one-pot transformation of 2-, 3-, and 4-aminopyridines, 2,6-diaminopyridines, and 2-aminoquinoline into the corresponding pyridinyl and quinolinyl trifluoromethanesulfonates and tosylates in solvents was developed. The procedure involves diazotization of the heterocyclic amines with sodium nitrite in mixed hexane-DMSO or hexane-DMF solutions in the presence of trifluoromethanesulfonic acid or p-toluenesulfonic acid. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Quality Control of 2-(m-Tolyl)pyridine).

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Quality Control of 2-(m-Tolyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem