Day: February 13, 2023

Biocorrosion of metal sewage treatment constructions and its inhibition with pyridinium chlorides was written by Bondar, Olena;Kurmakova, Iryna;Polevichenko, Sergey;Demchenko, Nataliya. And the article was included in Chemistry & Chemical Technology in 2017.Category: pyridine-derivatives This article mentions the following:

On the metal sewage treatment constructions (Chernihiv, Ukraine) a biofilm is formed, which is corrosive because of the number of sulfate-reducing bacteria (10⁷ cell/cm²). By affecting sulfate-reducing activity of microorganisms, pyridinium chlorides at the concentration of 0.5 g/l were revealed to provide St3ps steel inhibition efficiency of up to 98.7% under the corrosion caused by biofilm bacteria. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Category: pyridine-derivatives).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of 閳?8.7 鑴?10閳? cm3璺痬ol閳?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ璺痬ol閳? in the liquid phase and 140.4 kJ璺痬ol閳? in the gas phase. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C閳ユ弻 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Valorization of chitin derived N-acetyl-D-glucosamine into high valuable N-containing 3-acetamido-5-acetylfuran using pyridinium-based ionic liquids was written by Zang, Hongjun;Lou, Jing;Jiao, Shuolei;Li, Huanxin;Du, Yannan;Wang, Jiao. And the article was included in Journal of Molecular Liquids in 2021.Safety of Pyridinehydrochloride This article mentions the following:

A series of pyridinium-based ionic liquids were synthesized to directly catalyze the conversion of N-acetyl-D-glucosamine (NAG, the monomer of chitin) to 3-acetamido-5-acetylfuran (3A5AF). The yield of 3A5AF in 1-carboxymethyl pyridinium chloride ionic liquid reached 37.49%, without any additives. Using B₂O₃ and CaCl₂ as additives, the optimum yield increased to 67.37% at 180鎺矯 in 20 min. In addition, HPLC-MS anal. was utilized to elucidate the reaction mechanism. The research on turning “waste” into “wealth” opens up new ways for the utilization of biomass waste, which not only reduces environmental pollution but also has potential economic value. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Safety of Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Safety of Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Novel 1,4-dihydropyridine calcium antagonists. I. Synthesis and hypotensive activity of 4-(substituted pyridyl)-1,4-dihydropyridine derivatives was written by Ashimori, Atsuyuki;Ono, Taizo;Uchida, Takeshi;Ohtaki, Yutaka;Fukaya, Chikara;Watanabe, Masahiro;Yokoyama, Kazumasa. And the article was included in Chemical & Pharmaceutical Bulletin in 1990.SDS of cas: 116308-35-1 This article mentions the following:

A series of 4-(substituted pyridyl)-1,4-dihydropyridine derivatives I (R = H, halo, CF₃, etc.) were synthesized and their hypotensive effects examined Several compounds have a hypotensive activity parallel to that of nicardipine; the 4-(3-trifluoromethyl-2-pyridyl) and 4-(2-trifluoromethyl-3-pyridyl) derivatives, in particular, had approx. twice the duration of nicardipine, and the 4-(4-cyano-2-pyridyl) derivative had the most potent hypotensive activity of all the derivatives synthesized. In the experiment, the researchers used many compounds, for example, 2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1SDS of cas: 116308-35-1).

2-(Trifluoromethyl)nicotinaldehyde (cas: 116308-35-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.SDS of cas: 116308-35-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Co-oxidation of isomeric alkylpyridines was written by Matvienko, A. G.;Zalevskaya, N. M.;Efimova, I. V.;Nazarov, N. N.;Opeida, I. A.. And the article was included in Kinetika i Kataliz in 1984.Application In Synthesis of 2-Isopropylpyridine This article mentions the following:

The liquid-phase oxidation of binary mixtures of 3-isopropylpyridine with 2-, 3-, and 4-ethylpyridine and PhEt and of 3-ethylpyridine with isomeric isopropylpyridines was studied at 348 K. The results were combined with literature data to obtain rate constants for reactions of peroxy radicals with alkylpyridines and PhEt. The reactivity of isopropylpyridines toward primary and secondary peroxy radicals increased in the order 4- < 2- < 3-isomer; cumene was more reactive. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Application In Synthesis of 2-Isopropylpyridine).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Application In Synthesis of 2-Isopropylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Three-Point Hydrogen Bonding Assembly between a Conjugated PPV and a Functionalized Fullerene was written by Fang, Hongjuan;Wang, Shu;Xiao, Shengqiang;Yang, Junlin;Li, Yuliang;Shi, Zhiqiang;Li, Hongmei;Liu, Huibiao;Xiao, Shengxiong;Zhu, Daoben. And the article was included in Chemistry of Materials in 2003.Product Details of 1075-62-3 This article mentions the following:

A new self-assembly system between a PPV derivative and an organofullerene through a three-point hydrogen-bonding interaction was prepared The formation of hydrogen bonding was confirmed by ¹H NMR studies in CDCl₃. Fluorescence quenching experiments indicated that the fluorescence of uracil-containing polyphenylenevinylene derivative U-PPV was greatly quenched by 2,6-diacylamidopyridine-containing compound DAP-C₆₀ (K_SV = 5.8 鑴?10⁴ M^-1). In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3Product Details of 1075-62-3).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Product Details of 1075-62-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Expeditious and Solvent-Free Nickel-Catalyzed C-H Arylation of Arenes and Indoles was written by Jagtap, Rahul A.;Soni, Vineeta;Punji, Benudhar. And the article was included in ChemSusChem in 2017.Synthetic Route of C12H11N This article mentions the following:

An efficient solvent-free nickel-catalyzed method for C-H bond arylation of arenes and indoles was developed, which proceeds expeditiously through chelation assistance. The reaction is highly selective for mono-arylation and tolerates sensitive and structurally diverse functionalities, such as halides, ethers, amines, indole, pyrrole and carbazole. This reaction represents the first example of a nickel-catalyzed C-H arylation by monochelate assistance and symbolizes a rare precedent in solvent-free C-H arylation. Mechanistic studies by various controlled reactions, kinetic studies, and deuterium labeling experiments suggest that the arylation follows a single electron transfer (SET) pathway involving the turnover-limiting C-H nickelation process. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Synthetic Route of C12H11N).

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Synthetic Route of C12H11N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Modeling of the Effects of Ion Specificity on the Onset and Growth of Ionic Micelles in a Solution of Simple Salts was written by Koroleva, Sofia V.;Victorov, Alexey I.. And the article was included in Langmuir in 2014.Reference of 104-73-4 This article mentions the following:

A mol. thermodn. model has been developed that takes into account the effect of ion specificity on the free energy of aggregation. The specificity of salt is reflected by differences in the bare ionic sizes and polarizabilities leading to the difference in the dispersion interaction of ions with the aggregate. The model also contains parameters that characterize the compactness of ionic pairs formed between a mobile ion and surfactant’s headgroup. The values of these parameters show that more chaotropic heads form tighter pairs with chaotropic ions whereas more cosmotropic heads form more compact pairs with cosmotropic ions. The formation of compact pairs in the micelle corona diminishes the preferable curvature of the aggregates and promotes their growth. The model has been applied to aqueous solutions of cationic (alkyltrimethylammonium, alkyldimethylammonium, and alkylpyridinium) and anionic (alkylsulfate and alkylcarboxylate) surfactants in the presence of simple 1:1 salts. With a single set of parameter values, the model reproduces the critical micelle concentration-salinity curves and the sphere-to-rod transitions or the absence of thereof and describes the aggregate growth for different simple salts, in good agreement with experiment In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Reference of 104-73-4).

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C閳ユ弻 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Reference of 104-73-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

N-Vinyl and N-Aryl Hydroxypyridinium Ions: Charge-Activated Catalysts with Electron-Withdrawing Groups was written by Riegel, George F.;Kass, Steven R.. And the article was included in Journal of Organic Chemistry in 2020.Related Products of 626-64-2 This article mentions the following:

Charge-enhanced Bronsted acid organocatalysts with electron-withdrawing substituents were synthesized, and their relative acidities were characterized by computations, 1:1 binding equilibrium constants (K_1:1) with a UV-vis active sensor, ³¹P NMR shifts upon coordination with triethylphosphine oxide, and in one case by IR spectroscopy. Pseudo-first-order rate constants were determined for the Friedel-Crafts alkylations of N-methylindole with trans-灏?nitrostyrene and 2,2,2-trifluoroacetophenone and the Diels-Alder reaction of cyclopentadiene with Me vinyl ketone. These results along with kinetic isotope effect determinations revealed that the rate-determining step in the Friedel-Crafts transformations can shift from carbon-carbon bond formation to proton transfer to the catalyst’s conjugate base. This leads to an inverted parabolic reaction rate profile and slower reactions with more acidic catalysts in some cases. Electron-withdrawing groups placed on the N-vinyl and N-aryl substituents of hydroxypyridinium ion salts lead to enhanced acidities, more acidic catalysts than trifluoroacetic acid, and a linear correlation between the logarithms of the Diels-Alder rate constants and measured K_1:1 values. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Related Products of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Related Products of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Discovery of NLO Semiorganic (C₅H₆ON)⁺(H₂PO₄)^–: Dipole Moment Modulation and Superior Synergy in Solar-Blind UV Region was written by Lu, Jing;Liu, Xin;Zhao, Min;Deng, Xue-Bin;Shi, Ke-Xin;Wu, Qian-Ru;Chen, Ling;Wu, Li-Ming. And the article was included in Journal of the American Chemical Society in 2021.Quality Control of Pyridin-4-ol This article mentions the following:

We herein report a novel semiorg. NLO material, (C₅H₆ON)⁺(H₂PO₄)^–, 4HPP, showing promising excellent properties in the important solar-blind UV region where LAP and its deuterated form DLAP are the only commercialized semiorg. materials. For the first time, the 4-hydroxypyridine (4HP⁺, (C₅H₆ON)⁺) cation is identified as NLO active and how to eliminate the dipole-dipole interaction to avoid the unwanted center-symmetry-trap caused by the polar-induced susceptibility is well demonstrated. Remarkably, 4HPP exhibits competitive and even better properties compared with LAP that include better thermal stability (decomposition at 166 vs 112鎺矯 of LAP); wider transparency range (0.26-1.50娓璵); very strong SHG response (3 x KDP); a suitable large birefringence (铻杗_cal = 0.25 vs 0.075 of LAP); and a high laser-induced damage threshold (2.2 x KDP). First-principles calculations show that the 锜?conjugated organic (4HP)⁺ cation governs the optical anisotropy, whereas the synergy of the organic and inorganic moieties dominates the SHG process. Our discovery points out a new path for the rational design of high performance semiorg. materials that require an acentric structure. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Quality Control of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Quality Control of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Highly active recyclable heterogeneous Pd/ZnO nanoparticle catalyst: sustainable developments for the C-O and C-N bond cross-coupling reactions of aryl halides under ligand-free conditions was written by Hosseini-Sarvari, Mona;Razmi, Zahra. And the article was included in RSC Advances in 2014.Product Details of 4783-68-0 This article mentions the following:

Efficient Pd supported on ZnO nanoparticles for the ligand-free O-arylation and N-arylation of phenols and various N-H heterocycles with aryl chlorides, bromides, and iodides were readily synthesized and characterized. The amount of palladium on ZnO was 9.84 wt% (0.005 g of the catalyst contains 462 x 10^-8 mol% of Pd) which was determined by ICP anal. This nano sized Pd/ZnO with an average particle size of 20-25 nm and sp. surface area 40.61 m² g^-1 was used as a new reusable heterogeneous catalyst for the formation of C-O and C-N bonds in organic synthesis. This protocol gave the arylated product in satisfactory yields without any N₂ or Ar flow. The catalyst was recovered and recycled several times without marked loss of activity. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Product Details of 4783-68-0).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Product Details of 4783-68-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem