Day: February 13, 2023

Mechanochemical Solvent-Free Catalytic C-H Methylation was written by Ni, Shengjun;Hribersek, Matic;Baddigam, Swarna K.;Ingner, Fredric J. L.;Orthaber, Andreas;Gates, Paul J.;Pilarski, Lukasz T.. And the article was included in Angewandte Chemie, International Edition in 2021.SDS of cas: 4783-68-0 This article mentions the following:

The mechanochem., solvent-free, highly regioselective, rhodium-catalyzed C-H methylation of (hetero)arenes is reported. The reaction shows excellent functional-group compatibility and is demonstrated to work for the late-stage C-H methylation of biol. active compounds The method requires no external heating and benefits from considerably shorter reaction times than previous solution-based C-H methylation protocols. Addnl., the mechanochem. approach is shown to enable the efficient synthesis of organometallic complexes that are difficult to generate conventionally. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0SDS of cas: 4783-68-0).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.SDS of cas: 4783-68-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cooperation of biopolymer chitosan with hydrogen peroxide for ipso-hydroxylation of arylboronic acids under green conditions was written by Shin, Eun-Jae;Joo, Seong-Ryu;Kim, Seung-Hoi. And the article was included in Tetrahedron Letters in 2019.Recommanded Product: 51834-97-0 This article mentions the following:

Oxidative hydroxylation of arylboronic acids to the corresponding phenolic compounds R-OH [R = 2-MeC₆H₄, 2-naphthyl, 3-ClC₆H₄, etc.] under metal- and base-free aerobic conditions was successfully demonstrated using biopolymer support (chitosan or chitosan immobilized onto carbon nanotubes (CNT@Chitosan)). Hydrogen peroxide, as an eco-friendly oxidant, was compatible with the biopolymer supports and provided hydroxylation products in an efficient manner. The CNT@chitosan biopolymer support was particularly interesting for its potential recyclability. In the experiment, the researchers used many compounds, for example, 5-Hydroxy-2-methoxylpyridine (cas: 51834-97-0Recommanded Product: 51834-97-0).

5-Hydroxy-2-methoxylpyridine (cas: 51834-97-0) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 51834-97-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Analysis and optimisation of a novel “bio-brewery” approach: Production of bio-fuels and bio-chemicals by microwave-assisted, hydrothermal liquefaction of brewers’ spent grains was written by Lorente, Almudena;Remon, Javier;Budarin, Vitaliy L.;Sanchez-Verdu, Prado;Moreno, Andres;Clark, James H.. And the article was included in Energy Conversion and Management in 2019.Electric Literature of C8H11N This article mentions the following:

This work firstly explores the feasibility of using a novel microwave-assisted, catalyzed, hydrothermal process for the valorisation of brewers’ spent grains (BSGs), examining the effects of the temperature (180-250鎺矯), pressure (50-130 bar), reaction time (0-2 h) and catalyst amount (Ni-Co/Al-Mg, 0-0.25 g cat/g biomass). This route turned out to be a very promising approach for the production of bio-fuels (bio-oil and bio-char) and platform chems. (sugar rich aqueous solutions) in a single unit, helping the development of an innovative bio-refinery around BSGs. The overall conversion and the yields to gas, aqueous fraction and bio-oil varied by 31-68%, 10-33%, 9-48% and 4-14%, resp. The bio-oil was made up a complex mixture of phenols (0-26%), ketones (0-80%), aldehydes (0-57%), carboxylic acids (0-18%) and nitrogen compounds (0-76%). The proportions of C, H, N and O in the bio-oil varied as follow: 15-61 wt%, 5-10 wt%, 1-6 wt% and 26-77 wt%, resp., which shifted its higher heating value (HHV) between 9 and 27 MJ/kg. The liquid fraction comprised a mixture of DP > 6 oligosaccharides (67-98 C-weight%), DP2-6 oligosaccharides (0-10 C-weight%), saccharides (0.2-7 C-weight%), carboxylic acids (0-7 C-weight%) and furans (0-27 C-weight%). The spent solid after the experiments resembled an energetic like bio-char product, whose proportions of C, H, O and N varied by 35-72 wt%, 4-8 wt%, 1-4 wt% and 18-57 wt% and its HHV shifted between 9 and 32 MJ/kg. The optimization of the process revealed that using a temperature of 250鎺矯 and a pressure of 125 bar for 2 h, it is possible to convert the original material into high-energy biofuels: (8%) bio-oil (26 MJ/kg) and (35%) bio-char (32 MJ/kg); together with a (31%) saccharide-rich (>99 C-weight%) aqueous solution, thus converting this process into a very promising approach to achieve an environmentally-friendly and integral valorisation of brewers’ spent grains. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Electric Literature of C8H11N).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Electric Literature of C8H11N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Contact term contribution to lanthanide induced shifts in proton and carbon-13 NMR spectra of pyridine N-oxides was written by Tori, Kazuo;Yoshimura, Yohko;Kainosho, Masatsune;Ajisaka, Katsumi. And the article was included in Tetrahedron Letters in 1973.Quality Control of 3,5-Dimethylpyridine 1-oxide This article mentions the following:

Shifts induced by M(FOD)3, Eu(PTA)3, and M(DPM)3 (M = Eu, Pr, HFOD = 1,1,1,2,2,3,3-heptafluoro-7,7-dimethyloctane-4,6-dione, HPTA = pivaloyltrifluoroacetone, HDPM = dipivaloylmethane) in the 1H and 13C NMR of pyridine N-oxide and its alkyl derivatives included a contact term contribution. Upfield shifts were observed for the 灏?H and 绾?Me PMR signals and the directions of 13C shifts were those predicted for contact interaction. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Quality Control of 3,5-Dimethylpyridine 1-oxide).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Quality Control of 3,5-Dimethylpyridine 1-oxide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rh(III)-Catalyzed Regioselective Acetylation of sp² C-H Bond Starting from Paraformaldehyde was written by Wan, Ting;Du, Sidong;Pi, Chao;Wang, Yong;Li, Rongbin;Wu, Yangjie;Cui, Xiuling. And the article was included in ChemCatChem in 2019.Related Products of 4373-61-9 This article mentions the following:

Rh(III)-catalyzed acetylation of sp² C-H bonds has been realized using paraformaldehyde as an acetylating reagent. This procedure features simultaneous formation of two C-C bonds, external oxidants free, and water as the sole byproducts, thus offering an environmentally benign acetylation of arenes R¹R² (R¹ = pyridin-2-yl, 4-methylpyridin-2-yl, isoquinolin-1-yl; R² = Ph, 3-bromophenyl, 2,3-dihydro-1,4-benzodioxin-5-yl, etc.). A range of functional groups tolerance was observed In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Related Products of 4373-61-9).

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Related Products of 4373-61-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Alkylation of pyridine in free radical chain reactions utilizing alkylmercurials was written by Russell, Glen A.;Guo, Deliang;Khanna, Rajive K.. And the article was included in Journal of Organic Chemistry in 1985.HPLC of Formula: 644-98-4 This article mentions the following:

Pyridines or N,N,N‘,N‘-tetramethyl-p-phenylenediamine will undergo a photostimulated free radical chain reaction with alkylmercury halides or carboxylates yielding ring alkylated substitution products. Alkene mercuration products can be used without isolation for the alkylation reaction. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4HPLC of Formula: 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. HPLC of Formula: 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Metalation Studies of Carbophosphazene-Based Coordination Ligands: Metallacages to Polymeric Networks was written by Senapati, Tapas;Dey, Atanu;Kumar, Vierandra;Chandrasekhar, Vadapalli. And the article was included in Crystal Growth & Design in 2020.Safety of Pyridin-4-ol This article mentions the following:

The metalation behavior of [NC(NMe₂)]₂[NP(p-OC₅H₄N)₂] (L1) and [NC(NMe₂)]₂[NP(m-OC₅H₄N)₂] (L2) is described. The ligands L1 and L2 were prepared by the reaction of the carbophosphazene, [NC(NMe₂)]₂[NPCl₂] with 4-hydroxy pyridine or 3-hydroxy pyridine. The disposition of the coordinating nitrogen atoms does not allow the coordinating groups within the same mol. to bind to a single metal ion. This leads to the formation of mol. complexes (di- and tetranuclear) and coordination polymers (one- and two-dimensional). Thus, the interaction of L1 with a Hg(II) salt afforded a dinuclear complex, [Hg(Cl)₂(L1)]₂ (1). The reaction of L2 with Ag(I) salts afforded both dinuclear complexes and tetranuclear complexes, [Ag(CF₃SO₃)(L2)]₂ (2) and [Ag(NO₃)(L2)]₄璺?MeOH (3), resp. The reaction of copper acetate with L1 or L2 afforded one-dimensional polymeric networks [Cu₂(CH₃COO)₄(L1)]_n (4) and [Cu₂(CH₃COO)₄(L2)]_n (5). In 4 and 5, the basic dinuclear motif of copper acetate is preserved. In contrast to the reaction of L1 with HgCl₂ which afforded a dinuclear complex 1, a similar reaction with L2 resulted in a two-dimensional polymeric network, [Hg(Cl)₂(L2)]_n (6). Similarly, the interaction of L2 with CoCl₂ afforded a two-dimensional coordination polymer, [Co(Cl)₂(L2)₂]_n (7). The latter contains 40-membered metallacylces, which are fused to each other in the formation of the coordination polymer. The efficacy of the carbophosphazene based ligands [NC(NMe₂)]₂[NP(p-OC₅H₄N)₂] (L1) and [NC(NMe₂)]₂[NP(m-OC₅H₄N)₂] (L2) toward metalation is described. The different disposition of the coordinating groups (meta vs para) in the carbophosphazene based platform impacts a pivotal role toward metalation, resulting m mol. complexes to coordination polymers. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Safety of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of 閳?8.7 鑴?10閳? cm3璺痬ol閳?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ璺痬ol閳? in the liquid phase and 140.4 kJ璺痬ol閳? in the gas phase. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Safety of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis and characterization of new coordination polymers generated from oxadiazole-containing ligands and IIB metal ions was written by Cheng, Jun-Yan;Dong, Yu-Bin;Huang, Ru-Qi;Smith, Mark D.. And the article was included in Inorganica Chimica Acta in 2005.Recommanded Product: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole This article mentions the following:

The coordination chem. of the oxadiazole-containing rigid bidentate ligands 2,5-bis(4-pyridyl)-1,3,4-oxadiazole (L1) and 2,5-bis(3-pyridyl)-1,3,4-oxadiazole (L2) with inorganic IIB metal salts were studied. Five new coordination polymers (1–5) were prepared by solution reactions and fully characterized by IR spectroscopy, elemental anal., and single-crystal x-ray diffraction. Cd(L1)₂(MeCN)₂(ClO₄)₂璺?MeCN)₂ (1) crystallized in the monoclinic space group P2₁/c, a 8.4028(5), b 21.3726(13), c 10.5617(7) 鑴? 灏?95.1200(10)鎺? and Z = 2. In the solid state, it adopts an infinite two-dimensional polymeric structural motif with effective cross section of 閳?4.31 鑴?14.31 鑴? Cd(L2)(H₂O)(NO₃)₂ (2) crystallized in the monoclinic Ia, a 7.1203(5), b 22.2475(15), c 20.2652(16) 鑴? 灏?90.6080(10)鎺? and Z = 8. In the solid state, the two Cd(II) centers are connected to each other by L2 ligands and bridging nitrates into a two-dimensional network. [ZnCl₂(L1)] (3) and [HgI₂(L1)]璺疢eCN (4) crystallized in the monoclinic crystal system (3: space group P2₁/c, a 5.3702(3), b 20.4800(11), c 12.4093(7) 鑴? 灏?94.7930(10)鎺? and Z = 4; 4: space group P2/n, a 17.2733(11), b 5.2173(3), c 20.4069(13) 鑴? 灏?102.8690(10)鎺? and Z = 4). In the solid state, Zn(II) and Hg(II) metal centers are connected to each other by L1 ligands into a zigzag chain motif. Compound 5 (HgBr₂(L2) is different from 3 and 4, monoclinic, P2(1)/n, a 5.470(4), b 16.271(13), c 16.486(12) 鑴? 灏?93.197(15)鎺? and Z = 4) and adopts a novel 1-dimensional helical chain motif which resulted from the relative different coordinated orientation of the two N-donors on L2 ligand. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Recommanded Product: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Recommanded Product: 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gel polymer electrolyte based on polyvinylidenefluoride-co-hexafluoropropylene and ionic liquid for lithium ion battery was written by Yang, Pei Xia;Liu, Lei;Li, Li Bo;Hou, Jun;Xu, Yan Ping;Ren, Xuefeng;An, Mao Zhong;Li, Ning. And the article was included in Electrochimica Acta in 2014.Recommanded Product: 65350-59-6 This article mentions the following:

Gel-type polymer electrolytes with 1-butyl-4-methylpyridinium bis(trifluoromethanesulfonyl)imide (B4MePyTFSI) ionic liquid are formed by the solution casting method. The conductivity and transference number measurements are carried out to study conductivity and charge transport in the gel polymer electrolytes. The conductivity of the samples increases when the amount of B4MePyTFSI ionic liquid is increased. The Li ion ionic conductivity reaches the maximum value (2.01 鑴?10^-4 S cm^-1) when GPE contains 33.3% B4MePyTFSI. The electrochem. stability window of ILGPE is 閳?.5 V vs. Li⁺/Li at 20鎺? meeting the basic requirement of rechargeable Li batteries. Discharge performance of Li battery using this ILGPE membrane shows a capacity of 閳?60 mAh g^-1. The excellent performance with higher capacity, good cycle stability and compatibility are observed for the Li/ILGPE/LiFePO₄ cells. The interfacial resistances between ILGPE and electrodes have the less change after 10 cycles. In the experiment, the researchers used many compounds, for example, 1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6Recommanded Product: 65350-59-6).

1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 65350-59-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem