Day: February 13, 2023

Analysis of Hydrogen Bonding Network in the Systems Containing Chloride-Based Ionic Liquids with Cellulose/Cellobiose by Fourier-Transform Infrared Spectroscopy was written by Kashirskii, D. A.;Sashina, E. S.;Artamonova, T. V.;Myznikov, L. V.. And the article was included in Russian Journal of General Chemistry in 2018.Application of 125652-55-3 This article mentions the following:

Hydrogen bonds formed upon dissolution of cellulose and cellobiose in ionic liquids, 1-butyl-3-methylpyridinium and 1-butyl-3-methylimidazolium chlorides, were analyzed and characterized by means of Fourier-transform IR spectroscopy and quantum-chem. calculation The obtained data were used for assignment of absorption bands of individual OH groups and determination of hydrogen bonds energy in the solutions In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3Application of 125652-55-3).

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of 閳?8.7 鑴?10閳? cm3璺痬ol閳?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ璺痬ol閳? in the liquid phase and 140.4 kJ璺痬ol閳? in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 125652-55-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Understanding the Effects of Preorganization, Rigidity, and Steric Interactions in Synthetic Barbiturate Receptors was written by McGrath, Jacqueline M.;Pluth, Michael D.. And the article was included in Journal of Organic Chemistry in 2014.Name: N-(6-Aminopyridin-2-yl)acetamide This article mentions the following:

Synthetic barbiturate receptors have been utilized for many applications due to their high binding affinities for complementary guests. Although interest in this class of receptors spans from supramol. to materials chem., the effects of receptor steric bulk and preorganization on guest binding affinity has not been studied systematically. To investigate the roles that steric bulk and preorganization play in guest binding, we prepared a series of 12 deconstructed Hamilton receptors with varying degrees of steric bulk and preorganization. Both diethylbarbital and 3-methyl-7-propylxanthine were investigated as guests for the synthetic receptors. The stoichiometry of guest binding was investigated using Job plots for each host-guest pair, and ¹H NMR titrations were performed to measure the guest binding affinities. To complement the solution-state studies, DFT calculations at the B3LYP/6-31+G-(d,p) level of theory employing the IEF-PCM CHCl₃ solvation model were also performed. Calculated guest binding energies correlated well with the exptl. findings and provided addnl. insight into the factors influencing guest binding. Taken together, the results presented highlight the interplay between preorganization and steric interactions in establishing favorable interactions for self-assembled hydrogen-bonded systems. In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3Name: N-(6-Aminopyridin-2-yl)acetamide).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Name: N-(6-Aminopyridin-2-yl)acetamide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A new synthesis of 3,4-diaminothiophenes was written by Tominaga, Yoshinori;Fujito, Hiroshi;Matsuda, Yoshiro;Kobayashi, Goro. And the article was included in Heterocycles in 1977.SDS of cas: 17281-59-3 This article mentions the following:

Thiophenediamines I (R = CN, CONH₂, CO₂Et, Bz) were prepared by treating R¹CH₂CNCl^– (R¹ = pyridinio) with CS₂-NaOH, treating R¹C(CN):C(SNa)S^– with R²CH₂R (R² = Cl, Br), cyclizing R¹C(CN):C(S^–)SCH₂R with NEt₃, methylating ylides II (R³ = S^–), treating II (R³ = SMe) with MeNH₂-HCl and neutralizing. I condensed with R⁴COCOR⁴ (R⁴ = H, Me, Ph) to give the thienopyrazines III. In the experiment, the researchers used many compounds, for example, 1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3SDS of cas: 17281-59-3).

1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C閳ユ弻 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.SDS of cas: 17281-59-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Iron-Catalyzed Tunable and Site-Selective Olefin Transposition was written by Yu, Xiaolong;Zhao, Haonan;Li, Ping;Koh, Ming Joo. And the article was included in Journal of the American Chemical Society in 2020.Related Products of 85838-94-4 This article mentions the following:

The catalytic isomerization of C-C double bonds is an indispensable chem. transformation used to deliver higher-value analogs and has important utility in the chem. industry. Notwithstanding the advances reported in this field, there is compelling demand for a general catalytic solution that enables precise control of the C=C bond migration position, in both cyclic and acyclic systems, to furnish disubstituted and trisubstituted alkenes. Here, we show that catalytic amounts of an appropriate earth-abundant iron-based complex, a base and a boryl compound, promote efficient and controllable alkene transposition. Mechanistic investigations reveal that these processes likely involve in situ formation of an iron-hydride species which promotes olefin isomerization through sequential olefin insertion/灏?hydride elimination. Through this strategy, regiodivergent access to different products from one substrate can be facilitated, isomeric olefin mixtures commonly found in petroleum-derived feedstock can be transformed to a single alkene product, and unsaturated moieties embedded within linear and heterocyclic biol. active entities can be obtained. In the experiment, the researchers used many compounds, for example, tert-Butyl 5,6-dihydropyridine-1(2H)-carboxylate (cas: 85838-94-4Related Products of 85838-94-4).

tert-Butyl 5,6-dihydropyridine-1(2H)-carboxylate (cas: 85838-94-4) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ璺痬ol閳? in pyridine vs. 150 kJ璺痬ol閳? in benzene). Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Related Products of 85838-94-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Homogeneous epoxidation of lipophilic alkenes by aqueous hydrogen peroxide: catalysis of a Keggin-type phosphotungstate-functionalized ionic liquid in amphipathic ionic liquid solution was written by Wang, Sa-Sa;Liu, Wei;Wan, Qing-Xia;Liu, Ye. And the article was included in Green Chemistry in 2009.Formula: C17H30BrN This article mentions the following:

The ionic liquid compositions (ILC) composed of the Keggin-type phosphotungstate-functionalized ionic liquid of [Dopy]₃[PW₁₂O₄₀] and the amphipathic IL mixture of [Bpy]BF₄ and [Dopy]BF₄, were constructed as an effective catalytic system and ideal reaction medium for alkene epoxidation by aqueous H₂O₂, in which the real homogeneous catalysis was fulfilled with advantages of high activity, simplified work-up and available recyclability. The designing concept of the ILC and the IL effect on the activity/stability were discussed herein. In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Formula: C17H30BrN).

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Formula: C17H30BrN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Copper-catalyzed cyanation of heterocycle C-H bonds with ethyl(ethoxymethylene)cyanoacetate as a cyanating agent and its mechanism was written by Li, Ze-lin;Sun, Kang-kang;Cai, Chun. And the article was included in Organic Chemistry Frontiers in 2018.Application of 1620-76-4 This article mentions the following:

A method for synthesis of benzothiazole-2-carbonitriles such as I [R = H, 5-Cl, 6-Br, etc.; X = O, S], indole-3-carbonitriles II [R¹ = H, 6-MeO, 6-Cl; R² = H, Me; R³ = H, Me] and pyridine-2-carbonitriles III [R⁴ = H, 6-Me, 3-Br, etc.] was developed via copper-catalyzed cyanation of benzothiazoles/indoles/pyridines with ethyl(ethoxymethylene)cyanoacetate as a nontoxic and easily available cyanating agent. This transformation proceeded smoothly in the presence of di-tert-Bu peroxide (DTBP) with a wide substrate scope under ligand-free conditions. Mechanistic details were also described. In the experiment, the researchers used many compounds, for example, 4-Methylpicolinonitrile (cas: 1620-76-4Application of 1620-76-4).

4-Methylpicolinonitrile (cas: 1620-76-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application of 1620-76-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

An interpenetrating network poly(diethylene glycol carbonate)-based polymer electrolyte for solid state lithium batteries was written by Liu, Xiaochen;Ding, Guoliang;Zhou, Xinhong;Li, Shizhen;He, Weisheng;Chai, Jingchao;Pang, Chunguang;Liu, Zhihong;Cui, Guanglei. And the article was included in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2017.Related Products of 628-13-7 This article mentions the following:

Polycarbonate-based polymer electrolytes possess superior ionic conductivity at room temperature, higher Li ion transference number and wider electrochem. stability window when compared with conventional poly(ethylene oxide)-based polymer electrolytes. Here, the poly(diethylene glycol carbonate) dimethacrylate macromonomer (PDEC-DMA) was synthesized and the resultant interpenetrating network IPN-PDEC polymer electrolyte was developed via free radical in situ polymerization for polymer electrolyte Li metal batteries. This IPN-PDEC polymer electrolyte exhibited a decent ionic conductivity of 1.64 鑴?10^-4 S/cm at room temperature and a wide electrochem. stability window (閳?.5 V vs. Li⁺/Li). The LiFePO₄/IPN-PDEC/Li and LiFe_0.2Mn_0.8PO₄/IPN-PDEC/Li cells delivered excellent rate capability and cycling performance at room temperature An all solid state Li battery was also demonstrated by applying the as-prepared solid polymer electrolyte (SPE-PDEC) at 100鎺? which displayed a superior cycling performance. Therefore, the IPN-PDEC network is a promising polymer electrolyte for solid state Li batteries. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Related Products of 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Related Products of 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

An improved procedure for the preparation of aromatic heterocyclic N-oxides was written by Rhie, Soo Young;Ryu, Eung K.. And the article was included in Heterocycles in 1995.Safety of 3,5-Dimethylpyridine 1-oxide This article mentions the following:

Nitrogen-containing heterocyclic compounds gave their N-oxides in excellent yields by reaction with m-chloroperbenzoic acid in DMF/MeOH in the presence of HF. The presence of HF and MeOH is crucial for the reaction. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Safety of 3,5-Dimethylpyridine 1-oxide).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Safety of 3,5-Dimethylpyridine 1-oxide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cytotoxicity estimation of ionic liquids based on their effective structural features was written by Fatemi, Mohammad H.;Izadiyan, Parisa. And the article was included in Chemosphere in 2011.Product Details of 17281-59-3 This article mentions the following:

Cytotoxicity of a diverse set of 227 ionic liquids (taken from UFT/Merck Ionic Liquids Biol. Effects Database) containing 94 imidazolium, 53 pyridinium, 23 pyrrolidinium, 22 ammonium, 15 piperidinium, 10 morpholinium, 5 phosphanium, and 5 quinolinium cations in combination with 25 different types of anions to Leukemia Rat Cell Line (IPC-81) was estimated from their structural parameters using quant. structure – toxicity relationship “QSTR” methodol. Linear and nonlinear models were developed using genetic algorithm (GA), multiple linear regressions (MLR) and multilayer perceptron neural network (MLP NN) approaches. Robustness and reliability of the constructed models were evaluated through internal and external validation methods. Furthermore, chem. applicability domain was determined via leverage approach. In this work, it was revealed that the cationic moieties make the major contribution to cytotoxicity and the anionic parts play a secondary role in cytotoxicity of the ionic liquids studied here. Structural information represented in this work, can be used for a rational design of safer ILs. In the experiment, the researchers used many compounds, for example, 1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3Product Details of 17281-59-3).

1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Product Details of 17281-59-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A convenient synthesis of 3-substituted pipecolic acid methyl esters was written by Subramanyam, Chakrapani;Chattarjee, Sankar;Mallamo, John P.. And the article was included in Tetrahedron Letters in 1996.Recommanded Product: 59718-84-2 This article mentions the following:

A practical synthesis of the title compounds from com. available 3-hydroxy-2-pyridinecarboxylic acid is reported. The key step involves a Pd-catalyzed cross-coupling reaction of triflate I with the appropriate alkyl or aryl derivatives to generate substituted picolinic acid esters. Catalytic reduction of these esters provides the title compounds in good yields. In the experiment, the researchers used many compounds, for example, Methyl 3-methylpicolinate (cas: 59718-84-2Recommanded Product: 59718-84-2).

Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Recommanded Product: 59718-84-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem