Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 100-26-5, name is 2,5-Pyridinedicarboxylic acid. This compound has unique chemical properties. The synthetic route is as follows. Quality Control of 2,5-Pyridinedicarboxylic acid
General procedure: Synthesis of methyl ester derivatives of M6, M7, and M17 was carried out under catalytic esterification conditions as depicted in Scheme 1. To a solution of the appropriate carboxylic acid in methanol few drops of conc. sulfuric acid were added. Subsequently, the reaction mixture was refluxed for 6-10 h. After completion, the volatile solvents were evaporated under reduced pressure and the residue was dissolved in water/ethyl acetate mixture. The aqueous phase was extracted with ethyl acetate and the combined organic phase was washed with 5% sodium bicarbonate, brine, and was dried over anhydrous sodium sulfate. After filtration the desired ester was obtained using flash column chromatography.
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Reference:
Article; Luniwal, Amarjit; Wang, Lin; Pavlovsky, Alexander; Erhardt, Paul W.; Viola, Ronald E.; Bioorganic and Medicinal Chemistry; vol. 20; 9; (2012); p. 2950 – 2956;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem