Adding a certain compound to certain chemical reactions, such as: 117890-55-8, 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C8H8ClN, blongs to pyridine-derivatives compound. Computed Properties of C8H8ClN
A solution of m-chloroperbenzoic acid 70% (520.9 mg, 2.113 mmol) in 5 mL of CH2CI2 was added drop wise to a stirring solution of 2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine (295mg, 1.921 mmol) in 3 mL of CH2CI2 and the resulting solution was allowed to stir at room temperature overnight. The reaction mixture was quenched with a saturated aqueous solution of NaHCO3 and the CH2CI2 layer was separated. The aqueous phase was then extracted with CH2CI2 (3X), and the combined organic extracts were washed with brine and then dried over anhydrous Na2SO4. After removing solvent at reduced pressure, the residue was purified by preparative TLC (eluting with 70% EtOAc/Hexane) to afford the title compound (1-1 a).MS calculated = 169.91 , MS+1 observed =170.0
The synthetic route of 117890-55-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; PFIZER PRODUCTS INC.; WO2006/103511; (2006); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem