Electric Literature of 59237-53-5, Adding some certain compound to certain chemical reactions, such as: 59237-53-5, name is Methyl 6-chloro-5-nitronicotinate,molecular formula is C7H5ClN2O4, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 59237-53-5.
A suspension of methyl beta-chloro-S-nitronicotinate (1 eq), iron powder (5.2 eq), and NH4Cl3 (5.3 eq) in MeOH was heated at 75°C for 2 h. The mixture was passed through a pad of celite while hot and concentrated in vacuo to give methyl 5- amino-6-chloronicotinate (56 percent yield)
According to the analysis of related databases, 59237-53-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SIRTRIS PHARMACEUTICALS, INC.; OALMANN, Christopher; DISCH, Jeremy, S.; NG, Pui, Yee; PERNI, Robert, B.; WO2010/71853; (2010); A1;,
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