Synthetic Route of 58530-53-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 58530-53-3, name is 2,4-Dibromopyridine, molecular formula is C5H3Br2N, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Example 23 Synthesis of 1,1″-dihexyl-[4,2′:4′,4″-terpyridine]-1,1″-diium bis(tetrafluoroborate) A mixture of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (4.64 g, 22.6 mmol), 2,4-dibromopyridine (2.44 g, 10 mmol), Pd(PPh3)4 (0.59 g, 0.51 mmol, 5 mol %) and K2CO3 (3.12 g, 22.6 mmol) in degassed EtOH (50 mL) and PhMe (50 mL) under N2 was heated at reflux for 5 days, cooled, diluted with water (100 mL) and extracted with dichloromethane (4*75 mL). The dried (anhydrous sodium sulfate) solvent was removed in vacuo and the resulting brown powder chromatographed on silica, eluting with 5-10% MeOH in ethyl acetate. The solvent was removed to yield 4,2′:4′,4″-terpyridine as an off-white solid (2.07 g, 88.7%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 58530-53-3, 2,4-Dibromopyridine.
Reference:
Patent; Essilor International; ARCHAMBEAU, Samuel; BIVER, Claudine; BERIT-DEBAT, Fabien; AIKEN, Stuart; GABBUTT, Christopher David; HERON, Bernard Mark; BROADBENT, Thomas David; (37 pag.)US2018/194995; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem