A common compound: 108-75-8, name is 2,4,6-Trimethylpyridine,molecular formula is C8H11N, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below., 108-75-8
Step A. A solution of 2,4,6-collidine (1 mmole) in carbon tetrachloride was treated with NBS (5 mmole) and dibenzoyl peroxide (0.25 mmole) at 80 C. for 12 h.. The reaction mixture was cooled to 0 C. and the precipitate was filtered.. The filtrate was concentrated under vacuum.. Chromatography gave 2-bromomethyl-4,6-dimethylpyridine.
With the rapid development of chemical substances, we look forward to future research findings about 108-75-8.
Reference:
Patent; Metabasis Therapeutics, Inc.; US6756360; (2004); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem