Related Products of 63237-88-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 63237-88-7, name is Pyrazolo[1,5-a]pyridine-2-carboxylic acid. This compound has unique chemical properties. The synthetic route is as follows.
Pyrazolo[1,5-a]pyridine-2-carboxylic acid (J. Het. Chem., 18(6), 1981, 1149-1152, at page 1152) (81.8 mg, 0.50 mmol) was dissolved in 1-methyl-2-pyrrolidinone (3 mL) and the solution treated with 1-hydroxybenzotriazole hydrate (74.3 mg, 0.55 mmol) and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (115 mg, 0.60 mmol) and the mixture stirred at room temperature for 5 minutes. The mixture was then treated with the amine of preparation 18 (200 mg, 0.48 mmol) and N-ethyldiisopropylamine (155 mg, 1.20 mmol) and the reaction mixture stirred at room temperature for 48 hours. The reaction mixture was partitioned between ethyl acetate (75 mL) and water (75 mL) and the organic layer washed with water (3*50 mL) and 0.880 ammonia in water (100 mL), dried over magnesium sulphate and concentrated in vacuo. The residue was triturated with ether to yield the title product as a white solid, 223 mg. 1H-NMR(DMSO-D6, 400 MHz): 1.70(m, 8H), 2.41(s, 3H), 3.87(m, 1H), 3.98(m, 1H), 6.94(m, 2H), 7.00(m, 1H), 7.07(m, 2H), 7.38(m, 2H), 7.65(d, 1H), 7.74(m, 1H), 8.00(m, 1H), 8.22(m, 2H), 8.62(m, 1H). MS ES+ m/z 542 [MNa]+
According to the analysis of related databases, 63237-88-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Pfizer Inc; US2005/20626; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem