In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 52559-11-2, name is Pyridine-2,3,4-triamine, the common compound, a new synthetic route is introduced below. Computed Properties of C5H8N4
10. 6-(8-Amino-pyrido[2, S-typyrazinS-ytyS-trifluoromethyl-nicotinamide Dissolve 2,3,4-triaminopyridine (8 mmol) in water (20 mL). Add NaHCO3 (2.1 g, 25 mmol), dioxane (25 mL) and 6-(2-bromo-acetyl-5-trifluoromethyl)-nicotinamide (8 mmol), and stir at 100C for 4 hours. Cool the mixture and extract with EtOAc (4 x 10 mL). Wash the combined organic extracts with brine and dry over Na2SO4. Purify the residue by preparative HPLC to give the title compound.
The synthetic route of 52559-11-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; NEUROGEN CORPORATION; WO2006/42289; (2006); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem