Synthetic Route of 131747-53-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 131747-53-0, name is (6-(Trifluoromethyl)pyridin-2-yl)methanol, molecular formula is C7H6F3NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
a) 2-Chloro-4-((6-(trifluoromethyl)pyridin-2-yl)methoxy)pyridine 6-(Trifluoromethyl)-2-pyridinemethanol (2.20 g, 12.8 mmol) was reacted according to Example 113 (step c) to provide the title compound (3.30 g, 89%) as a white foam: ESI MS m/z 289 [M+H]+.
According to the analysis of related databases, 131747-53-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Albany Molecular Research, Inc.; SURMAN, Matthew D.; FREEMAN, Emily E.; GUZZO, Peter R.; HENDERSON, Alan J.; HADDEN, Mark; US2014/163012; (2014); A1;,
Pyridine – Wikipedia,
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