Electric Literature of 69045-83-6 ,Some common heterocyclic compound, 69045-83-6, molecular formula is C6H2Cl5N, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
After adding 26.5 g (0.1 mol) of 2,3-dichloro-5-trichloromethyl pyridine and 16 g (0.4 mol) of hydrazine hydrate 80% to the reaction kettle, 1000 ml of absolute ethanol was added and reacted at 30 C for 5 hours. Using HPLC analysis, after passing the control, The solvent is distilled off and the product is filtered under reduced pressure to give 2,3-dichloro-5-trichloromethylpyridine. The product yield is 95% and the purity is 99.15%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 69045-83-6, 2,3-Dichloro-5-(trichloromethyl)pyridine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Anhui Guoxing Biochemical Co., Ltd.; Gu Shunming; Zhao Weide; Fu Shenghui; Zhang Mingxiang; Zhao Guangfu; Xian Bin; (5 pag.)CN106748992; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem