624-28-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 624-28-2, name is 2,5-Dibromopyridine. This compound has unique chemical properties. The synthetic route is as follows.
Intermediate 16: N-methyl-5-(tributylstannyl)pyridin-2-amine 2,5-Dibromopyridine (6 g, 25 mmol) in 40 ml 33% CH3NH2 in ethanol (13 eq.) was heated at 80 C. for 60 hours. After evaporation the solid residue was suspended in CH2Cl2, extracted 3* with 1 N HCl. The combined aqueous phase was neutralized with 2 N NaOH (pH-10-11), and then back extracted 3* with CH2Cl2. The combined CH2Cl2 phase was washed with water and dried over sodium sulfate. Concentration gave 4.457 g of 5-bromo-N-methylpyridin-2-amine as off-white solid. (yield: 95.3%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 624-28-2, 2,5-Dibromopyridine.
Reference:
Patent; MacDonald, James E.; Jeffrey, McKelvy F.; Wong-Staal, Flossie; US2011/117055; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem