Application of 1-(Pyridin-3-yl)-1H-pyrazole-4-carboxylic acid

According to the analysis of related databases, 1014631-89-0, the application of this compound in the production field has become more and more popular.

Synthetic Route of 1014631-89-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1014631-89-0, name is 1-(Pyridin-3-yl)-1H-pyrazole-4-carboxylic acid. This compound has unique chemical properties. The synthetic route is as follows.

Stage 3: (Pyridin-3-yl)-1H-pyrazole-4-carbonyl chloride hydrochloride; 4.00 g (21.15 mmol) of 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid were initially charged in approx. 100 ml of dichloromethane, and admixed with 2 drops of dimethylformamide under argon. 7.783 g (61.32 mmol) of oxalyl chloride were added dropwise and, after the end of the addition, the mixture was stirred at room temperature for 1 hour. The solution was concentrated, and the residue was admixed with approx. 10 ml of toluene and concentrated. This gave a colourless solid which was converted further immediately.

According to the analysis of related databases, 1014631-89-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Bayer CropScience AG; US2011/118290; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem