Adding a certain compound to certain chemical reactions, such as: 117873-72-0, 2,6-Dibromo-4-methoxypyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 2,6-Dibromo-4-methoxypyridine, blongs to pyridine-derivatives compound. name: 2,6-Dibromo-4-methoxypyridine
A solution of 2.00 g 2,6-dibromo-4-methoxy-pyridine in 80 g liquid ammonia under was heated in an autoclave to 140 C. for 4 h. The reaction was cooled to room, evaporated and the residue was purified by silica column chromatography to yield 0.457 g of the title compound as white solid. MS (ISP) M+H+=203.2 205.5; 118b) 6-Bromo-4-methoxy-pyridin-2-ylamineA solution of 2.00 g 2,6-dibromo-4-methoxy-pyridine in 80 g liquid ammonia under was heated in an autoclave to 140 C. for 4 h. The reaction was cooled to room, evaporated and the residue was purified by silica column chromatography to yield 0.457 g of the title compound as white solid. MS (ISP) M+H+=203.2 205.5
At the same time, in my other blogs, there are other synthetic methods of this type of compound,117873-72-0, 2,6-Dibromo-4-methoxypyridine, and friends who are interested can also refer to it.
Reference:
Patent; Haap, Wolfgang; Hebeisen, Paul; Kitas, Eric A.; Kuhn, Bernd; Mohr, Peter; Wessel, Hans Peter; US2009/143439; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem