Adding a certain compound to certain chemical reactions, such as: 90395-45-2, 1-(4-(Pyridin-3-yl)phenyl)ethanone, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, HPLC of Formula: C13H11NO, blongs to pyridine-derivatives compound. HPLC of Formula: C13H11NO
1-(4-pyridin-3-ylphenyl)-ethanone(1-(4-Pyridin-3-yl-phenyl)-ethanone) (75g, 380.26mmole),3-bromobenzaldehyde(3-bromo-benzaldehyde) (67g, 362.16mmole),Add 1340 ml of ethanol and stir in the reaction flask.Finally, sodium tert-butoxide (52.7 g, 543.23 mmole) was added and stirred at room temperature.After the reaction has been completed, add 200 ml of deionized water and stir to filter.After filtering the solid with deionized water and methanol,The solid was then filtered with 100 ml of deionized water and 200 ml of methanol for 30 minutes.The solid was dried twice to obtain 78 g of pale yellow solid 3-(3-bromophenyl)-1-(4-pyridin-3-ylphenyl)-acetone(3-(3-bromo-phenyl)-1-(4-pyridin-3-ylphenyl)propanone),The yield was 88.7%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,90395-45-2, 1-(4-(Pyridin-3-yl)phenyl)ethanone, and friends who are interested can also refer to it.
Reference:
Patent; Yulei Optoelectric Technology Co., Ltd.; Huang Helong; Guo Huangming; Zhao Dengzhi; Lin Qizhen; Zhang Minzhong; (29 pag.)CN109988159; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem