Simple exploration of Pyridine-2-sulfonic acid

With the rapid development of chemical substances, we look forward to future research findings about 15103-48-7.

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 15103-48-7, name is Pyridine-2-sulfonic acid, molecular formula is C5H5NO3S, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. HPLC of Formula: C5H5NO3S

Pyridine-2-sulfonic acid (100 mg, 0.628 mmol) was dissolved inwater (15 ml) and added dropwise to the 7 ml of silver(I) nitrate aqueoussolution (106.7 mg; 0.628 mmol). The reaction mixture was stirredconstantly for 5 min and then allowed to stand at room temperature(pH=2.7) in the absence of light. Crystals formed by slow evaporation(after two weeks) were filtered off and used for further characterization. Yield: 57%. Elemental analysis (C5H4Ag1N1O3S1):Calcd (%) C 22.57; H 1.51; N 5.28; S 12.05 Found: C 22.50; H 1.30; N5.27; S 11.98; MS(-) m/z: 422.7 [2 M-Ag]-, 688.1 [3 M-Ag]-, 157.7[M-Ag]- (M=Ag(py-2-SO3)) (Fig. S1).

With the rapid development of chemical substances, we look forward to future research findings about 15103-48-7.

Reference:
Article; Rendo?ova, Michaela; Vargova, Zuzana; Sabolova, Danica; Imrichova, Natalia; Hudecova, Daniela; Gyepes, Robert; Lakato?, Boris; Elefantova, Katarina; Journal of Inorganic Biochemistry; vol. 186; (2018); p. 206 – 216;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem