Synthetic Route of 1401624-81-4, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 1401624-81-4 as follows.
A solution of 2,6-dlbromo-[1 ,2,4]trlazolo[i,5-a]pyrldlne (2.7 g, 9.7 mmol), triethylamlne (2.94 g, 29.1 mmol), and N-methylpiperazlne (1.94 g, 19.4 mmol) in toluene was refluxed overnight. The solvent was removed under vacuum, and the residue was purified by HPFC (PE: EA -1 : 1) to yield PZ972-3 (1.82 g, 63%). LC-MS: 296.1, 298.1 (M+l).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1401624-81-4, its application will become more common.
Reference:
Patent; PROZYMEX A/S; PEDERSEN, John; LAURITZEN, Conni; WO2012/130299; (2012); A1;,
Pyridine – Wikipedia,
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