Some scientific research about 4-Ethoxy-3-nitropyridine

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1796-84-5, 4-Ethoxy-3-nitropyridine, and friends who are interested can also refer to it.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1796-84-5, name is 4-Ethoxy-3-nitropyridine, molecular formula is C7H8N2O3, molecular weight is 168.15, as common compound, the synthetic route is as follows.Computed Properties of C7H8N2O3

A solution consisting of 4-ethoxy-3-nitropyridine (15.0 g, 97.3 MMOL) and EtNH2 (46.5 mL, 70% aq. solution, 584 MMOL) in ETOH (30 mL) was stirred at 85 C in a pressure vessel for 2 h. Removal of all VOLATILES IN VACUO afforded the title compound (16.2 g, 99 %). MS (ES+) m/z 168 (M+H) +.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1796-84-5, 4-Ethoxy-3-nitropyridine, and friends who are interested can also refer to it.

Reference:
Patent; SMITHKLINE BEECHAM CORPORATION; WO2005/11700; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem