Electric Literature of 169205-95-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 169205-95-2, name is 2-(Methylthio)oxazolo[4,5-b]pyridine, molecular formula is C7H6N2OS, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Step 3: Preparation of 2-morpholinooxazolo[4,5-b]pyridine To a solution of 2-(methylthio)oxazolo[4,5-b]pyridine (2.0g, 12.12 mmol) in THF (5mL) was added morpholine (5mL) and heated at 75 C overnight. The solvent was distilled off to afford the title compound (2.0g, 83.3%). 1HNMR (DMSO-d6, 300MHz): delta 8.20-8.10 (d, 1H), 7.80-7.70 (d, 1H), 7.15-7.00 (m, 1H), 3.75- 3.72 (m, 4H), 3.63-3.52 (m, 4H). LCMS: m/z: 206.5 (M+l) +.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 169205-95-2, 2-(Methylthio)oxazolo[4,5-b]pyridine.
Reference:
Patent; AURIGENE DISCOVERY TECHNOLOGIES LIMITED; GUMMADI, Venkateshwar, Rao; SAMAJDAR, Susanta; WO2015/104688; (2015); A1;,
Pyridine – Wikipedia,
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