Reference of 54-92-2, Adding some certain compound to certain chemical reactions, such as: 54-92-2, name is N’-Isopropylisonicotinohydrazide,molecular formula is C9H13N3O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 54-92-2.
A solution of 3-(2′,3′-dimethyl-biphenyl-2-yl)-propionic acid (127 mg, 0.50 mmoles) and isonicotinic acid N’-isopropyl-hydrazyde (ACROS) (167 mg, 0.60 mmoles) in DMF (5 mL) was treated with diisopropylethylamine (0.35 mL, 2.0 mmoles), and PyBroP (350 mg, 0.75 mmoles) at room temperature for 16 h. The reaction mixture was partitioned between 1N NaOH and ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated. The crude was absorbed on silica and purified on a silica gel column with 100% ethyl acetate to afford the product (17 mg, 8%). LC-MS m/e 416.49 (M+H+)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 54-92-2, N’-Isopropylisonicotinohydrazide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Michoud, Christophe; US2006/258740; (2006); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem