504-29-0, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 504-29-0, name is Pyridin-2-amine. A new synthetic method of this compound is introduced below.
a Pyridine-2-amino-5-sulphonic Acid 2-Aminopyridine (80 g, 0.85 mol) was added portionwise over 30 minutes to oleum (320 g) and the resulting solution heated at 140 C. for 4 hours. On cooling, the reaction was poured onto ice (200 g) and the mixture stirred in an ice/salt bath for a further 2 hours. The resulting suspension was filtered, the solid washed with ice water (200 ml) and cold IMS (200 ml) and dried under suction to afford the title compound as a solid, 111.3 g; LRMS: m/z 175 (M+1)+.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,504-29-0, Pyridin-2-amine, and friends who are interested can also refer to it.
Reference:
Patent; Grossman, Eric B.; Koppiker, Nandan P.; Leichter, Steven B.; US2003/162782; (2003); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem