Related Products of 905563-79-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 905563-79-3, name is 2-Chloro-4-methoxynicotinaldehyde, molecular formula is C7H6ClNO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Step 2: 2-Chloro-4-methoxypyridin-3-yl)methanol (26) A solution of 2-chloro-4-methoxynicotinaldehyde (0.190 g, 1.11 mmol) in methanol (10 mL) was treated with sodium borohydride (0.044 g, 1.2 mmol) and stirred at RT for 1 hour. The reaction was concentrated in vacuo, redissolved in ethyl acetate, washed with water and brine, dried over sodium sulfate, filtered and concentrated, providing the crude title compound which was used without further purification. LRMS m/z (M+H) 174.2 found, 174.1 required.
According to the analysis of related databases, 905563-79-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERCK SHARP & DOHME CORP.; KUDUK, Scott, D.; SKUDLAREK, Jason, W.; WO2014/176144; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem