Synthetic Route of 851484-95-2, Adding some certain compound to certain chemical reactions, such as: 851484-95-2, name is 2-Chloro-5-fluoronicotinaldehyde,molecular formula is C6H3ClFNO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 851484-95-2.
Example 37: Synthesis of 3-Fluoro-l,7,llb-triaza-benzo[c]fluorene-6-carboxylic acid ethyl es [0321] To a solution of compound SMI (0.8 g, 5 mmol) and compound SM2 (1.02 g, 5 mmol) in ethanol (50 mL) was added piperidine (1.28 g, 15 mmol) and the mixture was stirred at room temperature for 20 min. The reaction mixture was heated to reflux for 16h. After cooling, the mixture was filtered and washed with ethanol, dried to get compound 7A as yellow solid (0.82 g, 79 yield). LCMS: m/z 309.9 (M+H)+.
According to the analysis of related databases, 851484-95-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; HADDACH, Mustapha; WO2015/172123; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem