586-95-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 586-95-8, name is 4-Pyridinemethanol, molecular formula is C6H7NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: Catalyst 2b (1 mol%, 0.01 mmol), benzylalcohol (1.1 mmol), acetophenone (1.0 mmol), Cesiumcarbonate (1.0 mmol), and tert-amyl alcohol (2 mL) was added toa Schlenk tube under N2 atmosphere. The mixture was heated under 120oC for 24 h and then cooled to room temperature. Theresulting solution was directly purified by columnchromatography with petroleum ether/ethyl acetate (10:1) as eluent to give 1,3-diphenylpropan-1-one (5a) as awhite solid.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 586-95-8, 4-Pyridinemethanol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Wang, Dawei; Zhao, Keyan; Ma, Piming; Xu, Chongying; Ding, Yuqiang; Tetrahedron Letters; vol. 55; 52; (2014); p. 7233 – 7235;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem