Adding a certain compound to certain chemical reactions, such as: 1124-29-4, 5-Acetylpyridin-2(1H)-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C7H7NO2, blongs to pyridine-derivatives compound. Computed Properties of C7H7NO2
To a suspension of 5-acetylpyridin-2(lH)-one (500 mg, 3.6 mmol) in pyridine (4 mL) was added 0-(4-methoxybenzyl)hydroxylamine hydrochloride (761 mg, 4.0 mmol) and the reaction mixture was stirred at RT for 18 h. The mixture was then partitioned between CH2CI2 (10 mL) and 0 (10 mL), the organic layer was washed with 0 (2 x 10 mL), brine (2 x 10 mL), dried with Na2S04, filtered and concentrated under reduced pressure. The residue was triturated with toluene to give the title compound as a white solid (991 mg, 99%) MS (ES+) C15H16N2O3requires: 272, found: 273 [M+H]+.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,1124-29-4, 5-Acetylpyridin-2(1H)-one, and friends who are interested can also refer to it.
Reference:
Patent; JONES, Philip; DIFRANCESCO, Maria, Emilia; PETROCCHI, Alessia; MARSZALEK, Joe; LIU, Gang; KANG, Zhijun; CARROLL, Christopher, L.; MCAFOOS, Timothy; CZAKO, Barbara; WO2014/31928; (2014); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem