1206979-33-0, Adding a certain compound to certain chemical reactions, such as: 1206979-33-0, 6-Chloro-1H-pyrazolo[4,3-c]pyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 1206979-33-0, blongs to pyridine-derivatives compound.
A suspension of 6-chloro-lH-pyrazolo[4,3-c]pyridine (lg, 6.54mmol), l-(bromomethyl)-2- fluorobenzene (l . leq) and potassium carbonate (2eq) in acetonitrile (20mL) was heated at 60C for 18h. The resultant mixture was diluted with DCM and washed with H20. The organic phase was collected, dried (hydrophobic frit) and concentrated in vacuo. The resultant residue was purified by column chromatography (DCM:EtOAc) to give 6-chloro-l- (2-fluorobenzyl)-lH-pyrazolo[4,3-c]pyridine.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1206979-33-0, its application will become more common.
Reference:
Patent; CELLZOME LIMITED; OXENFORD, Sally; HOBSON, Andrew; OLIVER, Kathryn; RATCLIFFE, Andrew; RAMSDEN, Nigel; WO2013/17479; (2013); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem