Adding a certain compound to certain chemical reactions, such as: 59942-87-9, Pyrazolo[1,5-a]pyridin-2(1H)-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: Pyrazolo[1,5-a]pyridin-2(1H)-one, blongs to pyridine-derivatives compound. name: Pyrazolo[1,5-a]pyridin-2(1H)-one
General procedure: 12a. Synthesis of 2-(4-chlorobutoxy)pyrazolo[1 ,5-a]pyridine A solution of pyrazolo[1 ,5-a]pyridin-2-ol (776 mg, 5.78 mmol), K2C03 (2.4 g, 17.3 mmol), 1 -bromo-4-chlorobutane (1 .35 ml_, 1 1 .6 mmol) and sodium iodide (catalytic amount) in 20 ml_ of DMF was stirred for 18 h at room temperature. The resulting mixture was filtered, the solid washed with DMF and the organic filtrate concentrated. The residue was poured into diethyl ether and the generated precipitate filtered and discarded. The organic filtrate was washed with water and the organic layer dried (Na2S04) and concentrated under vacuum to afford 1 .35 g (quantitative) of brown oil.
The synthetic route of 59942-87-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; LABORATORIOS DEL DR. ESTEVE S.A.; DIAZ FERNANDEZ, Jose Luis; CUBERES ALTISENT, Mª Rosa; WO2013/124341; (2013); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem