So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Pocar, Donato; Stradi, Riccardo researched the compound: 1H-Pyrazole-5-carbaldehyde( cas:948552-36-1 ).Synthetic Route of C4H4N2O.They published the article 《Studies in the enamine field. XXXVII. Diene amines and arylsulfonyl azides》 about this compound( cas:948552-36-1 ) in Annali di Chimica (Rome, Italy). Keywords: diene amines sulfonyl azides pyrazoles; diazo propenes cyclization pyrazoles. We’ll tell you more about this compound (cas:948552-36-1).
Pyrazoles are prepared from amines RCH:CHCH:CHNR1R2 (I) and sulfonyl azides p-R3C6H4SO2N3 (II); formamidines p-R3C6H4SO2N:CHNR1R2 are by-products. The pyrazoles are formed by cyclization of diazo compounds RCH:CHCHN2. Thus, 1-diethylamino-1,3-butadiene is treated with p-ClC6H4SO2N3 at 0-10° to give pyrazole (III); p-ClC6H4SO2N:CHNEt2 is isolated. Similarly, IV and V are prepared from I (R = CHO, R1 = Me, R2 = Ph) and I (R = CH2OH, R1 = Me, R2 = Ph) and II (R3 = Me, NO2).
This literature about this compound(948552-36-1)Synthetic Route of C4H4N2Ohas given us a lot of inspiration, and I hope that the research on this compound(1H-Pyrazole-5-carbaldehyde) can be further advanced. Maybe we can get more compounds in a similar way.