Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 3375-31-3, is researched, Molecular C4H6O4Pd, about Palladium-catalyzed direct construction of oxazoline-containing polycyclic scaffolds via tandem addition/cyclization of nitriles and arylboronic acids, the main research direction is oxazoline polycyclic compound preparation palladium catalyst; heteroarene tethered acyl cyanohydrin arylboronic acid tandem addition cyclization.COA of Formula: C4H6O4Pd.
An efficient construction of oxazoline-containing polycyclic scaffolds is presented through a Pd-catalyzed addition/cyclization of (hetero)arene tethered O-acyl cyanohydrin units and arylboronic acids. Diverse oxazoline-containing polycyclic compounds can be prepared in good to high yields under mild reaction conditions. This method can be extended to prepare multi-substituted polycyclic heterocyclic compounds via a Pd-catalyzed addition/cyclization/arylation tandem sequence using arylboronic acid and different heteroarene scaffolds such as thiophene, pyrrole and furan analogs.
Different reactions of this compound(Palladium(II) acetate)COA of Formula: C4H6O4Pd require different conditions, so the reaction conditions are very important.