So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Xue, Dongxiang; Xu, Tiandan; Wang, Huixia; Wu, Meng; Yuan, Ya; Wang, Wei; Tan, Qiwen; Zhao, Fei; Zhou, Fang; Hu, Tao; Jiang, Zhongxing; Liu, Zhi-Jie; Zhao, Suwen; Liu, Dongsheng; Wuethrich, Kurt; Tao, Houchao researched the compound: 8-Bromooctan-1-ol( cas:50816-19-8 ).Category: pyridine-derivatives.They published the article 《Disulfide-Containing Detergents (DCDs) for the Structural Biology of Membrane Proteins》 about this compound( cas:50816-19-8 ) in Chemistry – A European Journal. Keywords: disulfide containing detergent structural biol membrane protein NMR; NMR spectroscopy; detergents; disulfides; membrane proteins; micelle size. We’ll tell you more about this compound (cas:50816-19-8).
Disulfide-containing detergents (DCDs) are introduced, which contain a disulfide bond in the hydrophobic tail. DCDs form smaller micelles than corresponding detergents with linear hydrocarbon chains, while providing good solubilization and reconstitution of membrane proteins. The use of this new class of detergents in structural biol. is illustrated with solution NMR spectra of the human G protein-coupled receptor A2AAR, which is an α-helical protein, and the β-barrel protein OmpX from E. coli.
Different reactions of this compound(8-Bromooctan-1-ol)Category: pyridine-derivatives require different conditions, so the reaction conditions are very important.