Adding a certain compound to certain chemical reactions, such as: 76102-92-6, 2-Amino-N-(pyridin-3-yl)benzamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C12H11N3O, blongs to pyridine-derivatives compound. Computed Properties of C12H11N3O
Example 30 To a solution of 180 mg of 2-[methyl(tetrahydro-2H-pyran-4-ylmethyl)amino]-1,3-thiazole-4-carboxylic acid in 1.2 ml of DMF were added 117 mg of 2-amino-N-pyridin-3-yl benzamide, 110 mg of WSC-HCl, and 100 mg of HOBt, followed by stirring at 60C for 3 days. To the reaction liquid was added an aqueous sodium hydrogen carbonate solution, and the resulting insoluble materials were collected by filtration. This was washed with acetonitrile to prepare 195 mg of 2-[methyl(tetrahydro-2H-pyran-4-ylmethyl)amino]-N-[2-(pyridin-3-ylcarbamoyl)phenyl]-1,3-thiazole-4-carboxamide.
The synthetic route of 76102-92-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Astellas Pharma Inc.; EP2206707; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem