Application of 754131-60-7, Adding some certain compound to certain chemical reactions, such as: 754131-60-7, name is 3-Bromo-2-(bromomethyl)pyridine,molecular formula is C6H5Br2N, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 754131-60-7.
To a solution of cis-4-phenylcyclohexanol (50.8 g) in THF (300 ml) was added 60%sodium hydride ( 17.29 g) at 0C, and the mixture was stirred for 30 min. To thereaction mixture was added 3-bromo-2-(bromomethyl)pyridine (72.3 g), and themixture was stirred at room temperature overnight. Saturated aqueous ammoniumchloride solution was added, and the mixture was extracted with ethyl acetate. Theextract was washed with saturated brine, dried over anhydrous magnesium sulfate andthe solvent was evaporated under reduced pressure. The residue was purified by silicagel column chromatography (ethyl acetate/hexane) to give the title compound (84.43g).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 754131-60-7, 3-Bromo-2-(bromomethyl)pyridine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; FUJIMOTO Tatsuhiko; RIKIMARU Kentaro; FUKUDA Koichiro; SUGIMOTO Hiromichi; MATSUMOTO Takahiro; TOKUNAGA Norihito; HIROZANE Mariko; (166 pag.)WO2017/135306; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem